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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COL2A1
Full Name:
Collagen alpha-1(II) chain
Alias:
Alpha-1 type II collagen
Type:
Mass (Da):
141785
Number AA:
1487
UniProt ID:
P02458
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
Q
D
V
Q
E
A
G
S
C
V
Q
D
G
Q
R
Site 2
S77
E
D
V
K
D
C
L
S
P
E
I
P
F
G
E
Site 3
T95
I
C
P
T
D
L
A
T
A
S
G
Q
P
G
P
Site 4
S97
P
T
D
L
A
T
A
S
G
Q
P
G
P
K
G
Site 5
T157
G
R
D
G
E
P
G
T
P
G
N
P
G
P
P
Site 6
S236
E
P
G
E
P
G
V
S
G
P
M
G
P
R
G
Site 7
T280
G
A
R
G
F
P
G
T
P
G
L
P
G
V
K
Site 8
Y292
G
V
K
G
H
R
G
Y
P
G
L
D
G
A
K
Site 9
S311
A
P
G
V
K
G
E
S
G
S
P
G
E
N
G
Site 10
S313
G
V
K
G
E
S
G
S
P
G
E
N
G
S
P
Site 11
S319
G
S
P
G
E
N
G
S
P
G
P
M
G
P
R
Site 12
T335
L
P
G
E
R
G
R
T
G
P
A
G
A
A
G
Site 13
T380
A
K
G
E
A
G
P
T
G
A
R
G
P
E
G
Site 14
T397
G
P
R
G
E
P
G
T
P
G
S
P
G
P
A
Site 15
S400
G
E
P
G
T
P
G
S
P
G
P
A
G
A
S
Site 16
S407
S
P
G
P
A
G
A
S
G
N
P
G
T
D
G
Site 17
T455
P
L
G
P
K
G
Q
T
G
E
P
G
I
A
G
Site 18
S536
A
P
G
E
R
G
P
S
G
L
A
G
P
K
G
Site 19
T563
L
P
G
A
R
G
L
T
G
R
P
G
D
A
G
Site 20
S578
P
Q
G
K
V
G
P
S
G
A
P
G
E
D
G
Site 21
T638
L
P
G
K
D
G
E
T
G
A
A
G
P
P
G
Site 22
S662
E
Q
G
A
P
G
P
S
G
F
Q
G
L
P
G
Site 23
S709
G
F
P
G
E
R
G
S
P
G
A
Q
G
L
Q
Site 24
T724
G
P
R
G
L
P
G
T
P
G
T
D
G
P
K
Site 25
T727
G
L
P
G
T
P
G
T
D
G
P
K
G
A
S
Site 26
S734
T
D
G
P
K
G
A
S
G
P
A
G
P
P
G
Site 27
T788
K
D
G
G
R
G
L
T
G
P
I
G
P
P
G
Site 28
S814
G
P
P
G
P
A
G
S
A
G
A
R
G
A
P
Site 29
T827
A
P
G
E
R
G
E
T
G
P
P
G
P
A
G
Site 30
S869
A
P
G
P
Q
G
P
S
G
A
P
G
P
Q
G
Site 31
S910
G
R
V
G
P
P
G
S
N
G
N
P
G
P
P
Site 32
S923
P
P
G
P
P
G
P
S
G
K
D
G
P
K
G
Site 33
S935
P
K
G
A
R
G
D
S
G
P
P
G
R
A
G
Site 34
S965
E
P
G
D
D
G
P
S
G
A
E
G
P
P
G
Site 35
S1001
F
P
G
L
P
G
P
S
G
E
P
G
K
Q
G
Site 36
S1013
K
Q
G
A
P
G
A
S
G
D
R
G
P
P
G
Site 37
S1039
G
E
P
G
R
E
G
S
P
G
A
D
G
P
P
Site 38
T1061
V
K
G
D
R
G
E
T
G
A
V
G
A
P
G
Site 39
S1075
G
A
P
G
P
P
G
S
P
G
P
A
G
P
T
Site 40
T1136
L
K
G
H
R
G
F
T
G
L
Q
G
L
P
G
Site 41
S1148
L
P
G
P
P
G
P
S
G
D
Q
G
A
S
G
Site 42
S1154
P
S
G
D
Q
G
A
S
G
P
A
G
P
S
G
Site 43
S1160
A
S
G
P
A
G
P
S
G
P
R
G
P
P
G
Site 44
S1172
P
P
G
P
V
G
P
S
G
K
D
G
A
N
G
Site 45
S1193
P
P
G
P
R
G
R
S
G
E
T
G
P
A
G
Site 46
Y1238
K
G
P
D
P
L
Q
Y
M
R
A
D
Q
A
A
Site 47
T1258
H
D
A
E
V
D
A
T
L
K
S
L
N
N
Q
Site 48
S1261
E
V
D
A
T
L
K
S
L
N
N
Q
I
E
S
Site 49
S1268
S
L
N
N
Q
I
E
S
I
R
S
P
E
G
S
Site 50
S1271
N
Q
I
E
S
I
R
S
P
E
G
S
R
K
N
Site 51
S1275
S
I
R
S
P
E
G
S
R
K
N
P
A
R
T
Site 52
Y1298
P
E
W
K
S
G
D
Y
W
I
D
P
N
Q
G
Site 53
T1307
I
D
P
N
Q
G
C
T
L
D
A
M
K
V
F
Site 54
Y1325
E
T
G
E
T
C
V
Y
P
N
P
A
N
V
P
Site 55
S1339
P
K
K
N
W
W
S
S
K
S
K
E
K
K
H
Site 56
Y1361
N
G
G
F
H
F
S
Y
G
D
D
N
L
A
P
Site 57
S1386
R
L
L
S
T
E
G
S
Q
N
I
T
Y
H
C
Site 58
Y1391
E
G
S
Q
N
I
T
Y
H
C
K
N
S
I
A
Site 59
S1416
K
A
L
L
I
Q
G
S
N
D
V
E
I
R
A
Site 60
S1427
E
I
R
A
E
G
N
S
R
F
T
Y
T
A
L
Site 61
T1430
A
E
G
N
S
R
F
T
Y
T
A
L
K
D
G
Site 62
Y1431
E
G
N
S
R
F
T
Y
T
A
L
K
D
G
C
Site 63
T1439
T
A
L
K
D
G
C
T
K
H
T
G
K
W
G
Site 64
T1448
H
T
G
K
W
G
K
T
V
I
E
Y
R
S
Q
Site 65
Y1452
W
G
K
T
V
I
E
Y
R
S
Q
K
T
S
R
Site 66
S1454
K
T
V
I
E
Y
R
S
Q
K
T
S
R
L
P
Site 67
S1458
E
Y
R
S
Q
K
T
S
R
L
P
I
I
D
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation