PhosphoNET

           
Protein Info 
   
Short Name:  CRYAB
Full Name:  Alpha-crystallin B chain
Alias:  Alpha crystallin B chain; Alpha(B)-crystallin; CRYA2; Crystallin, alpha B; Crystallin, alphaB; Heat shock protein beta-5; HSPB5; P23; Renal carcinoma antigen NY-REN-27; Rosenthal fiber component
Type:  Chaperone protein
Mass (Da):  20159
Number AA:  175
UniProt ID:  P02511
International Prot ID:  IPI00021369
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0042803  GO:0005212  GO:0051082 PhosphoSite+ KinaseNET
Biological Process:  GO:0006916  GO:0006936  GO:0032387 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S19RPFFPFHSPSRLFDQ
Site 2S21FFPFHSPSRLFDQFF
Site 3S35FGEHLLESDLFPTST
Site 4S41ESDLFPTSTSLSPFY
Site 5S43DLFPTSTSLSPFYLR
Site 6S45FPTSTSLSPFYLRPP
Site 7Y48STSLSPFYLRPPSFL
Site 8S53PFYLRPPSFLRAPSW
Site 9S59PSFLRAPSWFDTGLS
Site 10T63RAPSWFDTGLSEMRL
Site 11S66SWFDTGLSEMRLEKD
Site 12S76RLEKDRFSVNLDVKH
Site 13S85NLDVKHFSPEELKVK
Site 14Y122SREFHRKYRIPADVD
Site 15T132PADVDPLTITSSLSS
Site 16T134DVDPLTITSSLSSDG
Site 17S135VDPLTITSSLSSDGV
Site 18T144LSSDGVLTVNGPRKQ
Site 19S153NGPRKQVSGPERTIP
Site 20T162PERTIPITREEKPAV
Site 21T170REEKPAVTAAPKK__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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