PhosphoNET

           
Protein Info 
   
Short Name:  K14
Full Name:  Keratin, type I cytoskeletal 14
Alias:  CK14; CK-14; Cytokeratin-14; EBS3; EBS4; Epidermolysis bullosa simplex, Dowling-Meara, Koebner; K1C14; Keratin 14; Keratin-14; KRT14
Type:  Cytoskeletal protein
Mass (Da):  51561
Number AA:  472
UniProt ID:  P02533
International Prot ID:  IPI00384444
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0045095  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0005200   PhosphoSite+ KinaseNET
Biological Process:  GO:0008544  GO:0045110   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T9TTCSRQFTSSSSMKG
Site 2S10TCSRQFTSSSSMKGS
Site 3S11CSRQFTSSSSMKGSC
Site 4S12SRQFTSSSSMKGSCG
Site 5S13RQFTSSSSMKGSCGI
Site 6S17SSSSMKGSCGIGGGI
Site 7S28GGGIGGGSSRISSVL
Site 8S32GGGSSRISSVLAGGS
Site 9S33GGSSRISSVLAGGSC
Site 10S39SSVLAGGSCRAPSTY
Site 11S44GGSCRAPSTYGGGLS
Site 12T45GSCRAPSTYGGGLSV
Site 13Y46SCRAPSTYGGGLSVS
Site 14S51STYGGGLSVSSSRFS
Site 15S53YGGGLSVSSSRFSSG
Site 16S54GGGLSVSSSRFSSGG
Site 17S55GGLSVSSSRFSSGGA
Site 18S58SVSSSRFSSGGACGL
Site 19S74GGYGGGFSSSSSSFG
Site 20S75GYGGGFSSSSSSFGS
Site 21S76YGGGFSSSSSSFGSG
Site 22S77GGGFSSSSSSFGSGF
Site 23S78GGFSSSSSSFGSGFG
Site 24S79GFSSSSSSFGSGFGG
Site 25S82SSSSSFGSGFGGGYG
Site 26Y88GSGFGGGYGGGLGAG
Site 27S114GDGLLVGSEKVTMQN
Site 28T118LVGSEKVTMQNLNDR
Site 29S128NLNDRLASYLDKVRA
Site 30Y129LNDRLASYLDKVRAL
Site 31Y151EVKIRDWYQRQRPAE
Site 32Y162RPAEIKDYSPYFKTI
Site 33S163PAEIKDYSPYFKTIE
Site 34Y165EIKDYSPYFKTIEDL
Site 35T178DLRNKILTATVDNAN
Site 36T180RNKILTATVDNANVL
Site 37Y204ADDFRTKYETELNLR
Site 38T206DFRTKYETELNLRMS
Site 39S213TELNLRMSVEADING
Site 40T229RRVLDELTLARADLE
Site 41S241DLEMQIESLKEELAY
Site 42Y248SLKEELAYLKKNHEE
Site 43S281AAPGVDLSRILNEMR
Site 44Y291LNEMRDQYEKMAEKN
Site 45T308DAEEWFFTKTEELNR
Site 46T319ELNREVATNSELVQS
Site 47S321NREVATNSELVQSGK
Site 48S326TNSELVQSGKSEISE
Site 49S329ELVQSGKSEISELRR
Site 50S332QSGKSEISELRRTMQ
Site 51T337EISELRRTMQNLEIE
Site 52S350IELQSQLSMKASLEN
Site 53S354SQLSMKASLENSLEE
Site 54S358MKASLENSLEETKGR
Site 55T362LENSLEETKGRYCMQ
Site 56S379QIQEMIGSVEEQLAQ
Site 57Y398MEQQNQEYKILLDVK
Site 58T406KILLDVKTRLEQEIA
Site 59T414RLEQEIATYRRLLEG
Site 60Y415LEQEIATYRRLLEGE
Site 61S427EGEDAHLSSSQFSSG
Site 62S428GEDAHLSSSQFSSGS
Site 63S429EDAHLSSSQFSSGSQ
Site 64S432HLSSSQFSSGSQSSR
Site 65S433LSSSQFSSGSQSSRD
Site 66S435SSQFSSGSQSSRDVT
Site 67S437QFSSGSQSSRDVTSS
Site 68S438FSSGSQSSRDVTSSS
Site 69T442SQSSRDVTSSSRQIR
Site 70S444SSRDVTSSSRQIRTK
Site 71S445SRDVTSSSRQIRTKV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation