PhosphoNET

           
Protein Info 
   
Short Name:  K6a
Full Name:  Keratin, type II cytoskeletal 6A
Alias:  CK6A; CK6C; CK6D; K2C6A; K6C; K6D; keratin 6A; KRT6A; KRT6C; KRT6D
Type:  Cytoskeletal protein
Mass (Da):  60045
Number AA:  563
UniProt ID:  P02538
International Prot ID:  IPI00300725
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0045095     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0005200   PhosphoSite+ KinaseNET
Biological Process:  GO:0030154  GO:0007398  GO:0008284 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T6__MASTSTTIRSHSS
Site 2T7_MASTSTTIRSHSSS
Site 3S10STSTTIRSHSSSRRG
Site 4S12STTIRSHSSSRRGFS
Site 5S13TTIRSHSSSRRGFSA
Site 6S14TIRSHSSSRRGFSAN
Site 7S19SSSRRGFSANSARLP
Site 8S22RRGFSANSARLPGVS
Site 9S29SARLPGVSRSGFSSV
Site 10S31RLPGVSRSGFSSVSV
Site 11S34GVSRSGFSSVSVSRS
Site 12S35VSRSGFSSVSVSRSR
Site 13S37RSGFSSVSVSRSRGS
Site 14S39GFSSVSVSRSRGSGG
Site 15S41SSVSVSRSRGSGGLG
Site 16S44SVSRSRGSGGLGGAC
Site 17S58CGGAGFGSRSLYGLG
Site 18S60GAGFGSRSLYGLGGS
Site 19Y62GFGSRSLYGLGGSKR
Site 20S67SLYGLGGSKRISIGG
Site 21S71LGGSKRISIGGGSCA
Site 22S76RISIGGGSCAISGGY
Site 23S80GGGSCAISGGYGSRA
Site 24Y83SCAISGGYGSRAGGS
Site 25S85AISGGYGSRAGGSYG
Site 26S90YGSRAGGSYGFGGAG
Site 27Y91GSRAGGSYGFGGAGS
Site 28T155LNLQIDPTIQRVRAE
Site 29T169EEREQIKTLNNKFAS
Site 30S176TLNNKFASFIDKVRF
Site 31T196KVLETKWTLLQEQGT
Site 32T205LQEQGTKTVRQNLEP
Site 33S227NLRRQLDSIVGERGR
Site 34S237GERGRLDSELRGMQD
Site 35Y253VEDFKNKYEDEINKR
Site 36T269AAENEFVTLKKDVDA
Site 37Y278KKDVDAAYMNKVELQ
Site 38T290ELQAKADTLTDEINF
Site 39T292QAKADTLTDEINFLR
Site 40S307ALYDAELSQMQTHIS
Site 41T311AELSQMQTHISDTSV
Site 42S314SQMQTHISDTSVVLS
Site 43S317QTHISDTSVVLSMDN
Site 44S321SDTSVVLSMDNNRNL
Site 45S332NRNLDLDSIIAEVKA
Site 46Y341IAEVKAQYEEIAQRS
Site 47S354RSRAEAESWYQTKYE
Site 48Y356RAEAESWYQTKYEEL
Site 49T358EAESWYQTKYEELQV
Site 50Y360ESWYQTKYEELQVTA
Site 51T366KYEELQVTAGRHGDD
Site 52T377HGDDLRNTKQEIAEI
Site 53S393RMIQRLRSEIDHVKK
Site 54Y448LARLLKEYQELMNVK
Site 55Y465LDVEIATYRKLLEGE
Site 56T492NISVVQSTVSSGYGG
Site 57S494SVVQSTVSSGYGGAS
Site 58S501SSGYGGASGVGSGLG
Site 59S513GLGLGGGSSYSYGSG
Site 60S514LGLGGGSSYSYGSGL
Site 61Y515GLGGGSSYSYGSGLG
Site 62S516LGGGSSYSYGSGLGV
Site 63Y517GGGSSYSYGSGLGVG
Site 64S519GSSYSYGSGLGVGGG
Site 65S529GVGGGFSSSSGRAIG
Site 66S530VGGGFSSSSGRAIGG
Site 67S531GGGFSSSSGRAIGGG
Site 68S540RAIGGGLSSVGGGSS
Site 69S541AIGGGLSSVGGGSST
Site 70S547SSVGGGSSTIKYTTT
Site 71T548SVGGGSSTIKYTTTS
Site 72Y551GGSSTIKYTTTSSSS
Site 73T552GSSTIKYTTTSSSSR
Site 74T553SSTIKYTTTSSSSRK
Site 75T554STIKYTTTSSSSRKS
Site 76S555TIKYTTTSSSSRKSY
Site 77S556IKYTTTSSSSRKSYK
Site 78S557KYTTTSSSSRKSYKH
Site 79S558YTTTSSSSRKSYKH_
Site 80S561TSSSSRKSYKH____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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