PhosphoNET

           
Protein Info 
   
Short Name:  APOA1
Full Name:  Apolipoprotein A-I
Alias:  Apolipoprotein A-I
Type:  Lipid binding protein
Mass (Da):  30778
Number AA:  267
UniProt ID:  P02647
International Prot ID:  IPI00021841
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030139  GO:0005788  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0034191  GO:0001540  GO:0015485 PhosphoSite+ KinaseNET
Biological Process:  GO:0032488  GO:0007186  GO:0033344 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S30QQDEPPQSPWDRVKD
Site 2S49YVDVLKDSGRDYVSQ
Site 3Y53LKDSGRDYVSQFEGS
Site 4S55DSGRDYVSQFEGSAL
Site 5S60YVSQFEGSALGKQLN
Site 6S76KLLDNWDSVTSTFSK
Site 7T78LDNWDSVTSTFSKLR
Site 8T80NWDSVTSTFSKLREQ
Site 9S111EGLRQEMSKDLEEVK
Site 10Y124VKAKVQPYLDDFQKK
Site 11Y139WQEEMELYRQKVEPL
Site 12S166HELQEKLSPLGEEMR
Site 13T185AHVDALRTHLAPYSD
Site 14S191RTHLAPYSDELRQRL
Site 15Y216GGARLAEYHAKATEH
Site 16T221AEYHAKATEHLSTLS
Site 17S225AKATEHLSTLSEKAK
Site 18T226KATEHLSTLSEKAKP
Site 19S228TEHLSTLSEKAKPAL
Site 20S252VLESFKVSFLSALEE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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