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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FGA
Full Name:
Fibrinogen alpha chain
Alias:
FIBA; FIBA_HUMAN; fibrinogen alpha chain; Fibrinogen alpha/alpha-E chain precursor [Contains: Fibrinopeptide A]
Type:
Secreted protein
Mass (Da):
94973
Number AA:
866
UniProt ID:
P02671
International Prot ID:
IPI00021885
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009897
GO:0005577
GO:0031093
Uniprot
OncoNet
Molecular Function:
GO:0043499
GO:0030674
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0030168
GO:0051258
GO:0051592
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
G
T
A
W
T
A
D
S
G
E
G
D
F
L
A
Site 2
S45
R
V
V
E
R
H
Q
S
A
C
K
D
S
D
W
Site 3
Y62
C
S
D
E
D
W
N
Y
K
C
P
S
G
C
R
Site 4
T82
D
E
V
N
Q
D
F
T
N
R
I
N
K
L
K
Site 5
Y95
L
K
N
S
L
F
E
Y
Q
K
N
N
K
D
S
Site 6
S104
K
N
N
K
D
S
H
S
L
T
T
N
I
M
E
Site 7
T106
N
K
D
S
H
S
L
T
T
N
I
M
E
I
L
Site 8
S118
E
I
L
R
G
D
F
S
S
A
N
N
R
D
N
Site 9
S119
I
L
R
G
D
F
S
S
A
N
N
R
D
N
T
Site 10
T126
S
A
N
N
R
D
N
T
Y
N
R
V
S
E
D
Site 11
Y127
A
N
N
R
D
N
T
Y
N
R
V
S
E
D
L
Site 12
S131
D
N
T
Y
N
R
V
S
E
D
L
R
S
R
I
Site 13
S136
R
V
S
E
D
L
R
S
R
I
E
V
L
K
R
Site 14
S179
D
I
D
I
K
I
R
S
C
R
G
S
C
S
R
Site 15
S183
K
I
R
S
C
R
G
S
C
S
R
A
L
A
R
Site 16
S185
R
S
C
R
G
S
C
S
R
A
L
A
R
E
V
Site 17
Y197
R
E
V
D
L
K
D
Y
E
D
Q
Q
K
Q
L
Site 18
S239
L
V
P
G
N
F
K
S
Q
L
Q
K
V
P
P
Site 19
T270
R
P
G
G
N
E
I
T
R
G
G
S
T
S
Y
Site 20
S274
N
E
I
T
R
G
G
S
T
S
Y
G
T
G
S
Site 21
S276
I
T
R
G
G
S
T
S
Y
G
T
G
S
E
T
Site 22
Y277
T
R
G
G
S
T
S
Y
G
T
G
S
E
T
E
Site 23
S281
S
T
S
Y
G
T
G
S
E
T
E
S
P
R
N
Site 24
T283
S
Y
G
T
G
S
E
T
E
S
P
R
N
P
S
Site 25
S285
G
T
G
S
E
T
E
S
P
R
N
P
S
S
A
Site 26
S290
T
E
S
P
R
N
P
S
S
A
G
S
W
N
S
Site 27
S291
E
S
P
R
N
P
S
S
A
G
S
W
N
S
G
Site 28
S294
R
N
P
S
S
A
G
S
W
N
S
G
S
S
G
Site 29
S297
S
S
A
G
S
W
N
S
G
S
S
G
P
G
S
Site 30
S299
A
G
S
W
N
S
G
S
S
G
P
G
S
T
G
Site 31
S300
G
S
W
N
S
G
S
S
G
P
G
S
T
G
N
Site 32
S304
S
G
S
S
G
P
G
S
T
G
N
R
N
P
G
Site 33
T305
G
S
S
G
P
G
S
T
G
N
R
N
P
G
S
Site 34
S312
T
G
N
R
N
P
G
S
S
G
T
G
G
T
A
Site 35
S313
G
N
R
N
P
G
S
S
G
T
G
G
T
A
T
Site 36
T320
S
G
T
G
G
T
A
T
W
K
P
G
S
S
G
Site 37
S325
T
A
T
W
K
P
G
S
S
G
P
G
S
T
G
Site 38
S326
A
T
W
K
P
G
S
S
G
P
G
S
T
G
S
Site 39
S330
P
G
S
S
G
P
G
S
T
G
S
W
N
S
G
Site 40
T331
G
S
S
G
P
G
S
T
G
S
W
N
S
G
S
Site 41
S333
S
G
P
G
S
T
G
S
W
N
S
G
S
S
G
Site 42
S336
G
S
T
G
S
W
N
S
G
S
S
G
T
G
S
Site 43
S338
T
G
S
W
N
S
G
S
S
G
T
G
S
T
G
Site 44
S339
G
S
W
N
S
G
S
S
G
T
G
S
T
G
N
Site 45
S343
S
G
S
S
G
T
G
S
T
G
N
Q
N
P
G
Site 46
S351
T
G
N
Q
N
P
G
S
P
R
P
G
S
T
G
Site 47
S356
P
G
S
P
R
P
G
S
T
G
T
W
N
P
G
Site 48
T359
P
R
P
G
S
T
G
T
W
N
P
G
S
S
E
Site 49
S364
T
G
T
W
N
P
G
S
S
E
R
G
S
A
G
Site 50
S365
G
T
W
N
P
G
S
S
E
R
G
S
A
G
H
Site 51
S369
P
G
S
S
E
R
G
S
A
G
H
W
T
S
E
Site 52
T374
R
G
S
A
G
H
W
T
S
E
S
S
V
S
G
Site 53
S375
G
S
A
G
H
W
T
S
E
S
S
V
S
G
S
Site 54
S377
A
G
H
W
T
S
E
S
S
V
S
G
S
T
G
Site 55
S378
G
H
W
T
S
E
S
S
V
S
G
S
T
G
Q
Site 56
S380
W
T
S
E
S
S
V
S
G
S
T
G
Q
W
H
Site 57
S382
S
E
S
S
V
S
G
S
T
G
Q
W
H
S
E
Site 58
S388
G
S
T
G
Q
W
H
S
E
S
G
S
F
R
P
Site 59
S390
T
G
Q
W
H
S
E
S
G
S
F
R
P
D
S
Site 60
S392
Q
W
H
S
E
S
G
S
F
R
P
D
S
P
G
Site 61
S397
S
G
S
F
R
P
D
S
P
G
S
G
N
A
R
Site 62
S400
F
R
P
D
S
P
G
S
G
N
A
R
P
N
N
Site 63
T412
P
N
N
P
D
W
G
T
F
E
E
V
S
G
N
Site 64
S417
W
G
T
F
E
E
V
S
G
N
V
S
P
G
T
Site 65
S421
E
E
V
S
G
N
V
S
P
G
T
R
R
E
Y
Site 66
T424
S
G
N
V
S
P
G
T
R
R
E
Y
H
T
E
Site 67
Y428
S
P
G
T
R
R
E
Y
H
T
E
K
L
V
T
Site 68
T430
G
T
R
R
E
Y
H
T
E
K
L
V
T
S
K
Site 69
S451
T
G
K
E
K
V
T
S
G
S
T
T
T
T
R
Site 70
T455
K
V
T
S
G
S
T
T
T
T
R
R
S
C
S
Site 71
T456
V
T
S
G
S
T
T
T
T
R
R
S
C
S
K
Site 72
T457
T
S
G
S
T
T
T
T
R
R
S
C
S
K
T
Site 73
S460
S
T
T
T
T
R
R
S
C
S
K
T
V
T
K
Site 74
S462
T
T
T
R
R
S
C
S
K
T
V
T
K
T
V
Site 75
T464
T
R
R
S
C
S
K
T
V
T
K
T
V
I
G
Site 76
T466
R
S
C
S
K
T
V
T
K
T
V
I
G
P
D
Site 77
T468
C
S
K
T
V
T
K
T
V
I
G
P
D
G
H
Site 78
S485
V
T
K
E
V
V
T
S
E
D
G
S
D
C
P
Site 79
S489
V
V
T
S
E
D
G
S
D
C
P
E
A
M
D
Site 80
T499
P
E
A
M
D
L
G
T
L
S
G
I
G
T
L
Site 81
S501
A
M
D
L
G
T
L
S
G
I
G
T
L
D
G
Site 82
T505
G
T
L
S
G
I
G
T
L
D
G
F
R
H
R
Site 83
S524
A
A
F
F
D
T
A
S
T
G
K
T
F
P
G
Site 84
T528
D
T
A
S
T
G
K
T
F
P
G
F
F
S
P
Site 85
S542
P
M
L
G
E
F
V
S
E
T
E
S
R
G
S
Site 86
T544
L
G
E
F
V
S
E
T
E
S
R
G
S
E
S
Site 87
S546
E
F
V
S
E
T
E
S
R
G
S
E
S
G
I
Site 88
S549
S
E
T
E
S
R
G
S
E
S
G
I
F
T
N
Site 89
T555
G
S
E
S
G
I
F
T
N
T
K
E
S
S
S
Site 90
T557
E
S
G
I
F
T
N
T
K
E
S
S
S
H
H
Site 91
S560
I
F
T
N
T
K
E
S
S
S
H
H
P
G
I
Site 92
S561
F
T
N
T
K
E
S
S
S
H
H
P
G
I
A
Site 93
S562
T
N
T
K
E
S
S
S
H
H
P
G
I
A
E
Site 94
S572
P
G
I
A
E
F
P
S
R
G
K
S
S
S
Y
Site 95
S576
E
F
P
S
R
G
K
S
S
S
Y
S
K
Q
F
Site 96
S577
F
P
S
R
G
K
S
S
S
Y
S
K
Q
F
T
Site 97
S578
P
S
R
G
K
S
S
S
Y
S
K
Q
F
T
S
Site 98
S580
R
G
K
S
S
S
Y
S
K
Q
F
T
S
S
T
Site 99
T584
S
S
Y
S
K
Q
F
T
S
S
T
S
Y
N
R
Site 100
S585
S
Y
S
K
Q
F
T
S
S
T
S
Y
N
R
G
Site 101
S586
Y
S
K
Q
F
T
S
S
T
S
Y
N
R
G
D
Site 102
S588
K
Q
F
T
S
S
T
S
Y
N
R
G
D
S
T
Site 103
Y589
Q
F
T
S
S
T
S
Y
N
R
G
D
S
T
F
Site 104
S594
T
S
Y
N
R
G
D
S
T
F
E
S
K
S
Y
Site 105
T595
S
Y
N
R
G
D
S
T
F
E
S
K
S
Y
K
Site 106
S598
R
G
D
S
T
F
E
S
K
S
Y
K
M
A
D
Site 107
S600
D
S
T
F
E
S
K
S
Y
K
M
A
D
E
A
Site 108
Y601
S
T
F
E
S
K
S
Y
K
M
A
D
E
A
G
Site 109
S609
K
M
A
D
E
A
G
S
E
A
D
H
E
G
T
Site 110
S618
A
D
H
E
G
T
H
S
T
K
R
G
H
A
K
Site 111
S626
T
K
R
G
H
A
K
S
R
P
V
R
D
C
D
Site 112
S641
D
V
L
Q
T
H
P
S
G
T
Q
S
G
I
F
Site 113
S645
T
H
P
S
G
T
Q
S
G
I
F
N
I
K
L
Site 114
S660
P
G
S
S
K
I
F
S
V
Y
C
D
Q
E
T
Site 115
Y662
S
S
K
I
F
S
V
Y
C
D
Q
E
T
S
L
Site 116
Y692
F
N
R
T
W
Q
D
Y
K
R
G
F
G
S
L
Site 117
S698
D
Y
K
R
G
F
G
S
L
N
D
E
G
E
G
Site 118
Y713
E
F
W
L
G
N
D
Y
L
H
L
L
T
Q
R
Site 119
T718
N
D
Y
L
H
L
L
T
Q
R
G
S
V
L
R
Site 120
S722
H
L
L
T
Q
R
G
S
V
L
R
V
E
L
E
Site 121
Y740
G
N
E
A
Y
A
E
Y
H
F
R
V
G
S
E
Site 122
S746
E
Y
H
F
R
V
G
S
E
A
E
G
Y
A
L
Site 123
Y751
V
G
S
E
A
E
G
Y
A
L
Q
V
S
S
Y
Site 124
S756
E
G
Y
A
L
Q
V
S
S
Y
E
G
T
A
G
Site 125
S757
G
Y
A
L
Q
V
S
S
Y
E
G
T
A
G
D
Site 126
T761
Q
V
S
S
Y
E
G
T
A
G
D
A
L
I
E
Site 127
S770
G
D
A
L
I
E
G
S
V
E
E
G
A
E
Y
Site 128
Y777
S
V
E
E
G
A
E
Y
T
S
H
N
N
M
Q
Site 129
Y821
A
A
N
L
N
G
I
Y
Y
P
G
G
S
Y
D
Site 130
Y822
A
N
L
N
G
I
Y
Y
P
G
G
S
Y
D
P
Site 131
S826
G
I
Y
Y
P
G
G
S
Y
D
P
R
N
N
S
Site 132
S833
S
Y
D
P
R
N
N
S
P
Y
E
I
E
N
G
Site 133
Y835
D
P
R
N
N
S
P
Y
E
I
E
N
G
V
V
Site 134
S845
E
N
G
V
V
W
V
S
F
R
G
A
D
Y
S
Site 135
Y851
V
S
F
R
G
A
D
Y
S
L
R
A
V
R
M
Site 136
S852
S
F
R
G
A
D
Y
S
L
R
A
V
R
M
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation