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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FGB
Full Name:
Fibrinogen beta chain
Alias:
Type:
Mass (Da):
55928
Number AA:
491
UniProt ID:
P02675
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S42
D
N
E
E
G
F
F
S
A
R
G
H
R
P
L
Site 2
S58
K
K
R
E
E
A
P
S
L
R
P
A
P
P
P
Site 3
S67
R
P
A
P
P
P
I
S
G
G
G
Y
R
A
R
Site 4
Y71
P
P
I
S
G
G
G
Y
R
A
R
P
A
K
A
Site 5
S126
Q
E
R
P
I
R
N
S
V
D
E
L
N
N
N
Site 6
S138
N
N
N
V
E
A
V
S
Q
T
S
S
S
S
F
Site 7
T140
N
V
E
A
V
S
Q
T
S
S
S
S
F
Q
Y
Site 8
S141
V
E
A
V
S
Q
T
S
S
S
S
F
Q
Y
M
Site 9
S142
E
A
V
S
Q
T
S
S
S
S
F
Q
Y
M
Y
Site 10
S144
V
S
Q
T
S
S
S
S
F
Q
Y
M
Y
L
L
Site 11
Y147
T
S
S
S
S
F
Q
Y
M
Y
L
L
K
D
L
Site 12
Y149
S
S
S
F
Q
Y
M
Y
L
L
K
D
L
W
Q
Site 13
S173
E
N
V
V
N
E
Y
S
S
E
L
E
K
H
Q
Site 14
Y182
E
L
E
K
H
Q
L
Y
I
D
E
T
V
N
S
Site 15
T186
H
Q
L
Y
I
D
E
T
V
N
S
N
I
P
T
Site 16
S189
Y
I
D
E
T
V
N
S
N
I
P
T
N
L
R
Site 17
T193
T
V
N
S
N
I
P
T
N
L
R
V
L
R
S
Site 18
S200
T
N
L
R
V
L
R
S
I
L
E
N
L
R
S
Site 19
S207
S
I
L
E
N
L
R
S
K
I
Q
K
L
E
S
Site 20
S214
S
K
I
Q
K
L
E
S
D
V
S
A
Q
M
E
Site 21
S217
Q
K
L
E
S
D
V
S
A
Q
M
E
Y
C
R
Site 22
Y222
D
V
S
A
Q
M
E
Y
C
R
T
P
C
T
V
Site 23
T251
I
I
R
K
G
G
E
T
S
E
M
Y
L
I
Q
Site 24
Y255
G
G
E
T
S
E
M
Y
L
I
Q
P
D
S
S
Site 25
S261
M
Y
L
I
Q
P
D
S
S
V
K
P
Y
R
V
Site 26
S262
Y
L
I
Q
P
D
S
S
V
K
P
Y
R
V
Y
Site 27
Y266
P
D
S
S
V
K
P
Y
R
V
Y
C
D
M
N
Site 28
Y269
S
V
K
P
Y
R
V
Y
C
D
M
N
T
E
N
Site 29
S289
I
Q
N
R
Q
D
G
S
V
D
F
G
R
K
W
Site 30
Y299
F
G
R
K
W
D
P
Y
K
Q
G
F
G
N
V
Site 31
Y315
T
N
T
D
G
K
N
Y
C
G
L
P
G
E
Y
Site 32
S330
W
L
G
N
D
K
I
S
Q
L
T
R
M
G
P
Site 33
T333
N
D
K
I
S
Q
L
T
R
M
G
P
T
E
L
Site 34
T338
Q
L
T
R
M
G
P
T
E
L
L
I
E
M
E
Site 35
Y356
G
D
K
V
K
A
H
Y
G
G
F
T
V
Q
N
Site 36
T360
K
A
H
Y
G
G
F
T
V
Q
N
E
A
N
K
Site 37
Y368
V
Q
N
E
A
N
K
Y
Q
I
S
V
N
K
Y
Site 38
Y375
Y
Q
I
S
V
N
K
Y
R
G
T
A
G
N
A
Site 39
T378
S
V
N
K
Y
R
G
T
A
G
N
A
L
M
D
Site 40
S388
N
A
L
M
D
G
A
S
Q
L
M
G
E
N
R
Site 41
T396
Q
L
M
G
E
N
R
T
M
T
I
H
N
G
M
Site 42
Y408
N
G
M
F
F
S
T
Y
D
R
D
N
D
G
W
Site 43
T417
R
D
N
D
G
W
L
T
S
D
P
R
K
Q
C
Site 44
S418
D
N
D
G
W
L
T
S
D
P
R
K
Q
C
S
Site 45
S425
S
D
P
R
K
Q
C
S
K
E
D
G
G
G
W
Site 46
Y446
A
A
N
P
N
G
R
Y
Y
W
G
G
Q
Y
T
Site 47
Y452
R
Y
Y
W
G
G
Q
Y
T
W
D
M
A
K
H
Site 48
Y475
M
N
W
K
G
S
W
Y
S
M
R
K
M
S
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation