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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MBP
Full Name:
Myelin basic protein
Alias:
Myelin A1 protein; Myelin membrane encephalitogenic protein
Type:
Cytoskeletal protein
Mass (Da):
33117
Number AA:
304
UniProt ID:
P02686
International Prot ID:
IPI00021907
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0019911
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0006955
GO:0007268
Phosida
TranscriptoNet
STRING
Kinexus Products
Myelin basic protein (V228-P235, human) pT232 phosphopeptide - Powder PE-04AQS99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AQS99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
L
N
A
E
K
A
S
T
N
S
E
T
N
R
G
Site 2
T21
K
A
S
T
N
S
E
T
N
R
G
E
S
E
K
Site 3
S26
S
E
T
N
R
G
E
S
E
K
K
R
N
L
G
Site 4
S36
K
R
N
L
G
E
L
S
R
T
T
S
E
D
N
Site 5
T38
N
L
G
E
L
S
R
T
T
S
E
D
N
E
V
Site 6
T39
L
G
E
L
S
R
T
T
S
E
D
N
E
V
F
Site 7
S40
G
E
L
S
R
T
T
S
E
D
N
E
V
F
G
Site 8
S59
N
Q
N
N
G
T
S
S
Q
D
T
A
V
T
D
Site 9
T62
N
G
T
S
S
Q
D
T
A
V
T
D
S
K
R
Site 10
T65
S
S
Q
D
T
A
V
T
D
S
K
R
T
A
D
Site 11
S67
Q
D
T
A
V
T
D
S
K
R
T
A
D
P
K
Site 12
S87
A
H
P
A
D
P
G
S
R
P
H
L
I
R
L
Site 13
S96
P
H
L
I
R
L
F
S
R
D
A
P
G
R
E
Site 14
T106
A
P
G
R
E
D
N
T
F
K
D
R
P
S
E
Site 15
S112
N
T
F
K
D
R
P
S
E
S
D
E
L
Q
T
Site 16
S114
F
K
D
R
P
S
E
S
D
E
L
Q
T
I
Q
Site 17
S124
L
Q
T
I
Q
E
D
S
A
A
T
S
E
S
L
Site 18
S128
Q
E
D
S
A
A
T
S
E
S
L
D
V
M
A
Site 19
S130
D
S
A
A
T
S
E
S
L
D
V
M
A
S
Q
Site 20
S136
E
S
L
D
V
M
A
S
Q
K
R
P
S
Q
R
Site 21
S141
M
A
S
Q
K
R
P
S
Q
R
H
G
S
K
Y
Site 22
S146
R
P
S
Q
R
H
G
S
K
Y
L
A
T
A
S
Site 23
Y148
S
Q
R
H
G
S
K
Y
L
A
T
A
S
T
M
Site 24
T151
H
G
S
K
Y
L
A
T
A
S
T
M
D
H
A
Site 25
S153
S
K
Y
L
A
T
A
S
T
M
D
H
A
R
H
Site 26
T154
K
Y
L
A
T
A
S
T
M
D
H
A
R
H
G
Site 27
T169
F
L
P
R
H
R
D
T
G
I
L
D
S
I
G
Site 28
S174
R
D
T
G
I
L
D
S
I
G
R
F
F
G
G
Site 29
S190
R
G
A
P
K
R
G
S
G
K
D
S
H
H
P
Site 30
S194
K
R
G
S
G
K
D
S
H
H
P
A
R
T
A
Site 31
T200
D
S
H
H
P
A
R
T
A
H
Y
G
S
L
P
Site 32
Y203
H
P
A
R
T
A
H
Y
G
S
L
P
Q
K
S
Site 33
S205
A
R
T
A
H
Y
G
S
L
P
Q
K
S
H
G
Site 34
S210
Y
G
S
L
P
Q
K
S
H
G
R
T
Q
D
E
Site 35
T214
P
Q
K
S
H
G
R
T
Q
D
E
N
P
V
V
Site 36
T229
H
F
F
K
N
I
V
T
P
R
T
P
P
P
S
Site 37
T232
K
N
I
V
T
P
R
T
P
P
P
S
Q
G
K
Myelin basic protein (V228-P235, human) pT232 phosphopeptide - Powder PE-04AQS99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AQS99
Site 38
S236
T
P
R
T
P
P
P
S
Q
G
K
G
R
G
L
Site 39
S244
Q
G
K
G
R
G
L
S
L
S
R
F
S
W
G
Site 40
S246
K
G
R
G
L
S
L
S
R
F
S
W
G
A
E
Site 41
S249
G
L
S
L
S
R
F
S
W
G
A
E
G
Q
R
Site 42
Y261
G
Q
R
P
G
F
G
Y
G
G
R
A
S
D
Y
Site 43
S266
F
G
Y
G
G
R
A
S
D
Y
K
S
A
H
K
Site 44
Y268
Y
G
G
R
A
S
D
Y
K
S
A
H
K
G
F
Site 45
S270
G
R
A
S
D
Y
K
S
A
H
K
G
F
K
G
Site 46
T283
K
G
V
D
A
Q
G
T
L
S
K
I
F
K
L
Site 47
S285
V
D
A
Q
G
T
L
S
K
I
F
K
L
G
G
Site 48
S295
F
K
L
G
G
R
D
S
R
S
G
S
P
M
A
Site 49
S297
L
G
G
R
D
S
R
S
G
S
P
M
A
R
R
Site 50
S299
G
R
D
S
R
S
G
S
P
M
A
R
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation