PhosphoNET

           
Protein Info 
   
Short Name:  CRP
Full Name:  C-reactive protein
Alias: 
Type: 
Mass (Da):  25039
Number AA:  224
UniProt ID:  P02741
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S23AFGQTDMSRKAFVFP
Site 2S33AFVFPKESDTSYVSL
Site 3T35VFPKESDTSYVSLKA
Site 4S36FPKESDTSYVSLKAP
Site 5Y37PKESDTSYVSLKAPL
Site 6S39ESDTSYVSLKAPLTK
Site 7T59TVCLHFYTELSSTRG
Site 8S63HFYTELSSTRGYSIF
Site 9T64FYTELSSTRGYSIFS
Site 10Y67ELSSTRGYSIFSYAT
Site 11S68LSSTRGYSIFSYATK
Site 12S71TRGYSIFSYATKRQD
Site 13Y72RGYSIFSYATKRQDN
Site 14Y91FWSKDIGYSFTVGGS
Site 15S92WSKDIGYSFTVGGSE
Site 16S138GKPRVRKSLKKGYTV
Site 17T144KSLKKGYTVGAEASI
Site 18S159ILGQEQDSFGGNFEG
Site 19S167FGGNFEGSQSLVGDI
Site 20S169GNFEGSQSLVGDIGN
Site 21Y193PDEINTIYLGGPFSP
Site 22S199IYLGGPFSPNVLNWR
Site 23Y210LNWRALKYEVQGEVF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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