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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FN1
Full Name:
Fibronectin
Alias:
CIG; Cold-insoluble blobulin
Type:
Adhesion protein
Mass (Da):
262607
Number AA:
2386
UniProt ID:
P02751
International Prot ID:
IPI00022418
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005793
GO:0005577
GO:0031093
Uniprot
OncoNet
Molecular Function:
GO:0005518
GO:0005201
GO:0008201
PhosphoSite+
KinaseNET
Biological Process:
GO:0006953
GO:0016477
GO:0018149
Phosida
TranscriptoNet
STRING
Kinexus Products
Fibronectin (A1520-S1531, human) peptide - Powder PE-02AAE80#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-02AAE80
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
C
L
G
T
A
V
P
S
T
G
A
S
K
S
K
Site 2
T24
L
G
T
A
V
P
S
T
G
A
S
K
S
K
R
Site 3
S27
A
V
P
S
T
G
A
S
K
S
K
R
Q
A
Q
Site 4
S29
P
S
T
G
A
S
K
S
K
R
Q
A
Q
Q
M
Site 5
S41
Q
Q
M
V
Q
P
Q
S
P
V
A
V
S
Q
S
Site 6
S46
P
Q
S
P
V
A
V
S
Q
S
K
P
G
C
Y
Site 7
S48
S
P
V
A
V
S
Q
S
K
P
G
C
Y
D
N
Site 8
Y53
S
Q
S
K
P
G
C
Y
D
N
G
K
H
Y
Q
Site 9
Y69
N
Q
Q
W
E
R
T
Y
L
G
N
A
L
V
C
Site 10
S89
S
R
G
F
N
C
E
S
K
P
E
A
E
E
T
Site 11
T96
S
K
P
E
A
E
E
T
C
F
D
K
Y
T
G
Site 12
Y101
E
E
T
C
F
D
K
Y
T
G
N
T
Y
R
V
Site 13
Y106
D
K
Y
T
G
N
T
Y
R
V
G
D
T
Y
E
Site 14
Y112
T
Y
R
V
G
D
T
Y
E
R
P
K
D
S
M
Site 15
S134
G
A
G
R
G
R
I
S
C
T
I
A
N
R
C
Site 16
T136
G
R
G
R
I
S
C
T
I
A
N
R
C
H
E
Site 17
T153
Q
S
Y
K
I
G
D
T
W
R
R
P
H
E
T
Site 18
T160
T
W
R
R
P
H
E
T
G
G
Y
M
L
E
C
Site 19
Y163
R
P
H
E
T
G
G
Y
M
L
E
C
V
C
L
Site 20
T178
G
N
G
K
G
E
W
T
C
K
P
I
A
E
K
Site 21
Y195
D
H
A
A
G
T
S
Y
V
V
G
E
T
W
E
Site 22
T224
G
E
G
S
G
R
I
T
C
T
S
R
N
R
C
Site 23
T226
G
S
G
R
I
T
C
T
S
R
N
R
C
N
D
Site 24
T236
N
R
C
N
D
Q
D
T
R
T
S
Y
R
I
G
Site 25
T238
C
N
D
Q
D
T
R
T
S
Y
R
I
G
D
T
Site 26
Y240
D
Q
D
T
R
T
S
Y
R
I
G
D
T
W
S
Site 27
T245
T
S
Y
R
I
G
D
T
W
S
K
K
D
N
R
Site 28
T274
E
W
K
C
E
R
H
T
S
V
Q
T
T
S
S
Site 29
S275
W
K
C
E
R
H
T
S
V
Q
T
T
S
S
G
Site 30
T279
R
H
T
S
V
Q
T
T
S
S
G
S
G
P
F
Site 31
S281
T
S
V
Q
T
T
S
S
G
S
G
P
F
T
D
Site 32
T287
S
S
G
S
G
P
F
T
D
V
R
A
A
V
Y
Site 33
Y305
P
H
P
Q
P
P
P
Y
G
H
C
V
T
D
S
Site 34
T310
P
P
Y
G
H
C
V
T
D
S
G
V
V
Y
S
Site 35
T345
N
G
V
S
C
Q
E
T
A
V
T
Q
T
Y
G
Site 36
T348
S
C
Q
E
T
A
V
T
Q
T
Y
G
G
N
S
Site 37
T365
E
P
C
V
L
P
F
T
Y
N
G
R
T
F
Y
Site 38
Y372
T
Y
N
G
R
T
F
Y
S
C
T
T
E
G
R
Site 39
Y398
N
Y
E
Q
D
Q
K
Y
S
F
C
T
D
H
T
Site 40
T405
Y
S
F
C
T
D
H
T
V
L
V
Q
T
Q
G
Site 41
Y431
F
L
Y
N
N
H
N
Y
T
D
C
T
S
E
G
Site 42
Y452
W
C
G
T
T
Q
N
Y
D
A
D
Q
K
F
G
Site 43
T471
A
A
H
E
E
I
C
T
T
N
E
G
V
M
Y
Site 44
Y478
T
T
N
E
G
V
M
Y
R
I
G
D
Q
W
D
Site 45
S564
P
V
D
Q
C
Q
D
S
E
T
G
T
F
Y
Q
Site 46
T568
C
Q
D
S
E
T
G
T
F
Y
Q
I
G
D
S
Site 47
Y570
D
S
E
T
G
T
F
Y
Q
I
G
D
S
W
E
Site 48
Y579
I
G
D
S
W
E
K
Y
V
H
G
V
R
Y
Q
Site 49
Y585
K
Y
V
H
G
V
R
Y
Q
C
Y
C
Y
G
R
Site 50
Y588
H
G
V
R
Y
Q
C
Y
C
Y
G
R
G
I
G
Site 51
T604
W
H
C
Q
P
L
Q
T
Y
P
S
S
S
G
P
Site 52
Y605
H
C
Q
P
L
Q
T
Y
P
S
S
S
G
P
V
Site 53
S607
Q
P
L
Q
T
Y
P
S
S
S
G
P
V
E
V
Site 54
S608
P
L
Q
T
Y
P
S
S
S
G
P
V
E
V
F
Site 55
T617
G
P
V
E
V
F
I
T
E
T
P
S
Q
P
N
Site 56
T619
V
E
V
F
I
T
E
T
P
S
Q
P
N
S
H
Site 57
S621
V
F
I
T
E
T
P
S
Q
P
N
S
H
P
I
Site 58
S625
E
T
P
S
Q
P
N
S
H
P
I
Q
W
N
A
Site 59
Y641
Q
P
S
H
I
S
K
Y
I
L
R
W
R
P
K
Site 60
S650
L
R
W
R
P
K
N
S
V
G
R
W
K
E
A
Site 61
T658
V
G
R
W
K
E
A
T
I
P
G
H
L
N
S
Site 62
S665
T
I
P
G
H
L
N
S
Y
T
I
K
G
L
K
Site 63
Y666
I
P
G
H
L
N
S
Y
T
I
K
G
L
K
P
Site 64
T667
P
G
H
L
N
S
Y
T
I
K
G
L
K
P
G
Site 65
Y687
Q
L
I
S
I
Q
Q
Y
G
H
Q
E
V
T
R
Site 66
T699
V
T
R
F
D
F
T
T
T
S
T
S
T
P
V
Site 67
S701
R
F
D
F
T
T
T
S
T
S
T
P
V
T
S
Site 68
S703
D
F
T
T
T
S
T
S
T
P
V
T
S
N
T
Site 69
T704
F
T
T
T
S
T
S
T
P
V
T
S
N
T
V
Site 70
T707
T
S
T
S
T
P
V
T
S
N
T
V
T
G
E
Site 71
S708
S
T
S
T
P
V
T
S
N
T
V
T
G
E
T
Site 72
T710
S
T
P
V
T
S
N
T
V
T
G
E
T
T
P
Site 73
T712
P
V
T
S
N
T
V
T
G
E
T
T
P
F
S
Site 74
T715
S
N
T
V
T
G
E
T
T
P
F
S
P
L
V
Site 75
S719
T
G
E
T
T
P
F
S
P
L
V
A
T
S
E
Site 76
T746
S
W
V
S
A
S
D
T
V
S
G
F
R
V
E
Site 77
S748
V
S
A
S
D
T
V
S
G
F
R
V
E
Y
E
Site 78
Y754
V
S
G
F
R
V
E
Y
E
L
S
E
E
G
D
Site 79
S757
F
R
V
E
Y
E
L
S
E
E
G
D
E
P
Q
Site 80
Y765
E
E
G
D
E
P
Q
Y
L
D
L
P
S
T
A
Site 81
S770
P
Q
Y
L
D
L
P
S
T
A
T
S
V
N
I
Site 82
T771
Q
Y
L
D
L
P
S
T
A
T
S
V
N
I
P
Site 83
Y791
R
K
Y
I
V
N
V
Y
Q
I
S
E
D
G
E
Site 84
S800
I
S
E
D
G
E
Q
S
L
I
L
S
T
S
Q
Site 85
S804
G
E
Q
S
L
I
L
S
T
S
Q
T
T
A
P
Site 86
S806
Q
S
L
I
L
S
T
S
Q
T
T
A
P
D
A
Site 87
T808
L
I
L
S
T
S
Q
T
T
A
P
D
A
P
P
Site 88
T818
P
D
A
P
P
D
P
T
V
D
Q
V
D
D
T
Site 89
T825
T
V
D
Q
V
D
D
T
S
I
V
V
R
W
S
Site 90
S826
V
D
Q
V
D
D
T
S
I
V
V
R
W
S
R
Site 91
S832
T
S
I
V
V
R
W
S
R
P
Q
A
P
I
T
Site 92
T839
S
R
P
Q
A
P
I
T
G
Y
R
I
V
Y
S
Site 93
Y841
P
Q
A
P
I
T
G
Y
R
I
V
Y
S
P
S
Site 94
Y845
I
T
G
Y
R
I
V
Y
S
P
S
V
E
G
S
Site 95
S846
T
G
Y
R
I
V
Y
S
P
S
V
E
G
S
S
Site 96
S848
Y
R
I
V
Y
S
P
S
V
E
G
S
S
T
E
Site 97
S852
Y
S
P
S
V
E
G
S
S
T
E
L
N
L
P
Site 98
T854
P
S
V
E
G
S
S
T
E
L
N
L
P
E
T
Site 99
T861
T
E
L
N
L
P
E
T
A
N
S
V
T
L
S
Site 100
S864
N
L
P
E
T
A
N
S
V
T
L
S
D
L
Q
Site 101
S868
T
A
N
S
V
T
L
S
D
L
Q
P
G
V
Q
Site 102
T890
V
E
E
N
Q
E
S
T
P
V
V
I
Q
Q
E
Site 103
T901
I
Q
Q
E
T
T
G
T
P
R
S
D
T
V
P
Site 104
S904
E
T
T
G
T
P
R
S
D
T
V
P
S
P
R
Site 105
T906
T
G
T
P
R
S
D
T
V
P
S
P
R
D
L
Site 106
S909
P
R
S
D
T
V
P
S
P
R
D
L
Q
F
V
Site 107
T935
T
P
P
E
S
A
V
T
G
Y
R
V
D
V
I
Site 108
Y937
P
E
S
A
V
T
G
Y
R
V
D
V
I
P
V
Site 109
S957
H
G
Q
R
L
P
I
S
R
N
T
F
A
E
V
Site 110
T960
R
L
P
I
S
R
N
T
F
A
E
V
T
G
L
Site 111
S968
F
A
E
V
T
G
L
S
P
G
V
T
Y
Y
F
Site 112
T972
T
G
L
S
P
G
V
T
Y
Y
F
K
V
F
A
Site 113
S981
Y
F
K
V
F
A
V
S
H
G
R
E
S
K
P
Site 114
S986
A
V
S
H
G
R
E
S
K
P
L
T
A
Q
Q
Site 115
T990
G
R
E
S
K
P
L
T
A
Q
Q
T
T
K
L
Site 116
T1012
F
V
N
E
T
D
S
T
V
L
V
R
W
T
P
Site 117
T1018
S
T
V
L
V
R
W
T
P
P
R
A
Q
I
T
Site 118
T1030
Q
I
T
G
Y
R
L
T
V
G
L
T
R
R
G
Site 119
T1034
Y
R
L
T
V
G
L
T
R
R
G
Q
P
R
Q
Site 120
Y1042
R
R
G
Q
P
R
Q
Y
N
V
G
P
S
V
S
Site 121
S1047
R
Q
Y
N
V
G
P
S
V
S
K
Y
P
L
R
Site 122
Y1051
V
G
P
S
V
S
K
Y
P
L
R
N
L
Q
P
Site 123
S1060
L
R
N
L
Q
P
A
S
E
Y
T
V
S
L
V
Site 124
S1075
A
I
K
G
N
Q
E
S
P
K
A
T
G
V
F
Site 125
T1079
N
Q
E
S
P
K
A
T
G
V
F
T
T
L
Q
Site 126
S1089
F
T
T
L
Q
P
G
S
S
I
P
P
Y
N
T
Site 127
S1090
T
T
L
Q
P
G
S
S
I
P
P
Y
N
T
E
Site 128
Y1094
P
G
S
S
I
P
P
Y
N
T
E
V
T
E
T
Site 129
S1122
F
K
L
G
V
R
P
S
Q
G
G
E
A
P
R
Site 130
T1132
G
E
A
P
R
E
V
T
S
D
S
G
S
I
V
Site 131
S1133
E
A
P
R
E
V
T
S
D
S
G
S
I
V
V
Site 132
S1135
P
R
E
V
T
S
D
S
G
S
I
V
V
S
G
Site 133
Y1151
T
P
G
V
E
Y
V
Y
T
I
Q
V
L
R
D
Site 134
T1152
P
G
V
E
Y
V
Y
T
I
Q
V
L
R
D
G
Site 135
S1175
N
K
V
V
T
P
L
S
P
P
T
N
L
H
L
Site 136
T1188
H
L
E
A
N
P
D
T
G
V
L
T
V
S
W
Site 137
T1192
N
P
D
T
G
V
L
T
V
S
W
E
R
S
T
Site 138
S1194
D
T
G
V
L
T
V
S
W
E
R
S
T
T
P
Site 139
S1198
L
T
V
S
W
E
R
S
T
T
P
D
I
T
G
Site 140
T1199
T
V
S
W
E
R
S
T
T
P
D
I
T
G
Y
Site 141
T1200
V
S
W
E
R
S
T
T
P
D
I
T
G
Y
R
Site 142
Y1206
T
T
P
D
I
T
G
Y
R
I
T
T
T
P
T
Site 143
T1209
D
I
T
G
Y
R
I
T
T
T
P
T
N
G
Q
Site 144
T1210
I
T
G
Y
R
I
T
T
T
P
T
N
G
Q
Q
Site 145
T1211
T
G
Y
R
I
T
T
T
P
T
N
G
Q
Q
G
Site 146
S1220
T
N
G
Q
Q
G
N
S
L
E
E
V
V
H
A
Site 147
S1230
E
V
V
H
A
D
Q
S
S
C
T
F
D
N
L
Site 148
T1233
H
A
D
Q
S
S
C
T
F
D
N
L
S
P
G
Site 149
S1238
S
C
T
F
D
N
L
S
P
G
L
E
Y
N
V
Site 150
S1246
P
G
L
E
Y
N
V
S
V
Y
T
V
K
D
D
Site 151
S1256
T
V
K
D
D
K
E
S
V
P
I
S
D
T
I
Site 152
T1271
I
P
A
V
P
P
P
T
D
L
R
F
T
N
I
Site 153
T1276
P
P
T
D
L
R
F
T
N
I
G
P
D
T
M
Site 154
T1286
G
P
D
T
M
R
V
T
W
A
P
P
P
S
I
Site 155
T1296
P
P
P
S
I
D
L
T
N
F
L
V
R
Y
S
Site 156
S1303
T
N
F
L
V
R
Y
S
P
V
K
N
E
E
D
Site 157
S1315
E
E
D
V
A
E
L
S
I
S
P
S
D
N
A
Site 158
S1337
P
G
T
E
Y
V
V
S
V
S
S
V
Y
E
Q
Site 159
S1340
E
Y
V
V
S
V
S
S
V
Y
E
Q
H
E
S
Site 160
S1347
S
V
Y
E
Q
H
E
S
T
P
L
R
G
R
Q
Site 161
T1348
V
Y
E
Q
H
E
S
T
P
L
R
G
R
Q
K
Site 162
T1356
P
L
R
G
R
Q
K
T
G
L
D
S
P
T
G
Site 163
S1360
R
Q
K
T
G
L
D
S
P
T
G
I
D
F
S
Site 164
T1362
K
T
G
L
D
S
P
T
G
I
D
F
S
D
I
Site 165
S1367
S
P
T
G
I
D
F
S
D
I
T
A
N
S
F
Site 166
T1384
H
W
I
A
P
R
A
T
I
T
G
Y
R
I
R
Site 167
S1398
R
H
H
P
E
H
F
S
G
R
P
R
E
D
R
Site 168
S1409
R
E
D
R
V
P
H
S
R
N
S
I
T
L
T
Site 169
S1412
R
V
P
H
S
R
N
S
I
T
L
T
N
L
T
Site 170
T1414
P
H
S
R
N
S
I
T
L
T
N
L
T
P
G
Site 171
T1416
S
R
N
S
I
T
L
T
N
L
T
P
G
T
E
Site 172
S1437
A
L
N
G
R
E
E
S
P
L
L
I
G
Q
Q
Site 173
S1445
P
L
L
I
G
Q
Q
S
T
V
S
D
V
P
R
Site 174
T1446
L
L
I
G
Q
Q
S
T
V
S
D
V
P
R
D
Site 175
T1474
S
W
D
A
P
A
V
T
V
R
Y
Y
R
I
T
Site 176
Y1477
A
P
A
V
T
V
R
Y
Y
R
I
T
Y
G
E
Site 177
Y1478
P
A
V
T
V
R
Y
Y
R
I
T
Y
G
E
T
Site 178
T1481
T
V
R
Y
Y
R
I
T
Y
G
E
T
G
G
N
Site 179
Y1482
V
R
Y
Y
R
I
T
Y
G
E
T
G
G
N
S
Site 180
S1489
Y
G
E
T
G
G
N
S
P
V
Q
E
F
T
V
Site 181
T1495
N
S
P
V
Q
E
F
T
V
P
G
S
K
S
T
Site 182
S1499
Q
E
F
T
V
P
G
S
K
S
T
A
T
I
S
Site 183
T1504
P
G
S
K
S
T
A
T
I
S
G
L
K
P
G
Site 184
S1506
S
K
S
T
A
T
I
S
G
L
K
P
G
V
D
Site 185
S1527
A
V
T
G
R
G
D
S
P
A
S
S
K
P
I
Site 186
S1530
G
R
G
D
S
P
A
S
S
K
P
I
S
I
N
Site 187
S1531
R
G
D
S
P
A
S
S
K
P
I
S
I
N
Y
Site 188
S1535
P
A
S
S
K
P
I
S
I
N
Y
R
T
E
I
Site 189
T1540
P
I
S
I
N
Y
R
T
E
I
D
K
P
S
Q
Site 190
S1546
R
T
E
I
D
K
P
S
Q
M
Q
V
T
D
V
Site 191
S1559
D
V
Q
D
N
S
I
S
V
K
W
L
P
S
S
Site 192
S1565
I
S
V
K
W
L
P
S
S
S
P
V
T
G
Y
Site 193
S1566
S
V
K
W
L
P
S
S
S
P
V
T
G
Y
R
Site 194
S1567
V
K
W
L
P
S
S
S
P
V
T
G
Y
R
V
Site 195
T1570
L
P
S
S
S
P
V
T
G
Y
R
V
T
T
T
Site 196
Y1572
S
S
S
P
V
T
G
Y
R
V
T
T
T
P
K
Site 197
T1575
P
V
T
G
Y
R
V
T
T
T
P
K
N
G
P
Site 198
T1576
V
T
G
Y
R
V
T
T
T
P
K
N
G
P
G
Site 199
T1577
T
G
Y
R
V
T
T
T
P
K
N
G
P
G
P
Site 200
T1587
N
G
P
G
P
T
K
T
K
T
A
G
P
D
Q
Site 201
T1589
P
G
P
T
K
T
K
T
A
G
P
D
Q
T
E
Site 202
T1595
K
T
A
G
P
D
Q
T
E
M
T
I
E
G
L
Site 203
S1611
P
T
V
E
Y
V
V
S
V
Y
A
Q
N
P
S
Site 204
S1618
S
V
Y
A
Q
N
P
S
G
E
S
Q
P
L
V
Site 205
S1647
F
T
D
V
D
V
D
S
I
K
I
A
W
E
S
Site 206
S1654
S
I
K
I
A
W
E
S
P
Q
G
Q
V
S
R
Site 207
S1660
E
S
P
Q
G
Q
V
S
R
Y
R
V
T
Y
S
Site 208
Y1662
P
Q
G
Q
V
S
R
Y
R
V
T
Y
S
S
P
Site 209
T1665
Q
V
S
R
Y
R
V
T
Y
S
S
P
E
D
G
Site 210
Y1666
V
S
R
Y
R
V
T
Y
S
S
P
E
D
G
I
Site 211
S1668
R
Y
R
V
T
Y
S
S
P
E
D
G
I
H
E
Site 212
S1701
P
G
S
E
Y
T
V
S
V
V
A
L
H
D
D
Site 213
S1711
A
L
H
D
D
M
E
S
Q
P
L
I
G
T
Q
Site 214
S1719
Q
P
L
I
G
T
Q
S
T
A
I
P
A
P
T
Site 215
T1734
D
L
K
F
T
Q
V
T
P
T
S
L
S
A
Q
Site 216
S1737
F
T
Q
V
T
P
T
S
L
S
A
Q
W
T
P
Site 217
S1739
Q
V
T
P
T
S
L
S
A
Q
W
T
P
P
N
Site 218
T1743
T
S
L
S
A
Q
W
T
P
P
N
V
Q
L
T
Site 219
Y1752
P
N
V
Q
L
T
G
Y
R
V
R
V
T
P
K
Site 220
T1757
T
G
Y
R
V
R
V
T
P
K
E
K
T
G
P
Site 221
T1762
R
V
T
P
K
E
K
T
G
P
M
K
E
I
N
Site 222
T1786
V
S
G
L
M
V
A
T
K
Y
E
V
S
V
Y
Site 223
Y1793
T
K
Y
E
V
S
V
Y
A
L
K
D
T
L
T
Site 224
T1798
S
V
Y
A
L
K
D
T
L
T
S
R
P
A
Q
Site 225
T1800
Y
A
L
K
D
T
L
T
S
R
P
A
Q
G
V
Site 226
S1815
V
T
T
L
E
N
V
S
P
P
R
R
A
R
V
Site 227
T1823
P
P
R
R
A
R
V
T
D
A
T
E
T
T
I
Site 228
T1826
R
A
R
V
T
D
A
T
E
T
T
I
T
I
S
Site 229
T1831
D
A
T
E
T
T
I
T
I
S
W
R
T
K
T
Site 230
S1833
T
E
T
T
I
T
I
S
W
R
T
K
T
E
T
Site 231
T1838
T
I
S
W
R
T
K
T
E
T
I
T
G
F
Q
Site 232
T1840
S
W
R
T
K
T
E
T
I
T
G
F
Q
V
D
Site 233
T1842
R
T
K
T
E
T
I
T
G
F
Q
V
D
A
V
Site 234
T1855
A
V
P
A
N
G
Q
T
P
I
Q
R
T
I
K
Site 235
T1860
G
Q
T
P
I
Q
R
T
I
K
P
D
V
R
S
Site 236
S1867
T
I
K
P
D
V
R
S
Y
T
I
T
G
L
Q
Site 237
Y1868
I
K
P
D
V
R
S
Y
T
I
T
G
L
Q
P
Site 238
T1869
K
P
D
V
R
S
Y
T
I
T
G
L
Q
P
G
Site 239
T1871
D
V
R
S
Y
T
I
T
G
L
Q
P
G
T
D
Site 240
T1877
I
T
G
L
Q
P
G
T
D
Y
K
I
Y
L
Y
Site 241
Y1879
G
L
Q
P
G
T
D
Y
K
I
Y
L
Y
T
L
Site 242
Y1882
P
G
T
D
Y
K
I
Y
L
Y
T
L
N
D
N
Site 243
Y1884
T
D
Y
K
I
Y
L
Y
T
L
N
D
N
A
R
Site 244
S1893
L
N
D
N
A
R
S
S
P
V
V
I
D
A
S
Site 245
S1922
T
P
N
S
L
L
V
S
W
Q
P
P
R
A
R
Site 246
T1931
Q
P
P
R
A
R
I
T
G
Y
I
I
K
Y
E
Site 247
Y1937
I
T
G
Y
I
I
K
Y
E
K
P
G
S
P
P
Site 248
S1942
I
K
Y
E
K
P
G
S
P
P
R
E
V
V
P
Site 249
T1961
G
V
T
E
A
T
I
T
G
L
E
P
G
T
E
Site 250
Y1972
P
G
T
E
Y
T
I
Y
V
I
A
L
K
N
N
Site 251
S1982
A
L
K
N
N
Q
K
S
E
P
L
I
G
R
K
Site 252
T1991
P
L
I
G
R
K
K
T
D
E
L
P
Q
L
V
Site 253
S2015
P
E
I
L
D
V
P
S
T
V
Q
K
T
P
F
Site 254
T2020
V
P
S
T
V
Q
K
T
P
F
V
T
H
P
G
Site 255
Y2028
P
F
V
T
H
P
G
Y
D
T
G
N
G
I
Q
Site 256
T2039
N
G
I
Q
L
P
G
T
S
G
Q
Q
P
S
V
Site 257
S2045
G
T
S
G
Q
Q
P
S
V
G
Q
Q
M
I
F
Site 258
T2060
E
E
H
G
F
R
R
T
T
P
P
T
T
A
T
Site 259
T2061
E
H
G
F
R
R
T
T
P
P
T
T
A
T
P
Site 260
T2064
F
R
R
T
T
P
P
T
T
A
T
P
I
R
H
Site 261
T2065
R
R
T
T
P
P
T
T
A
T
P
I
R
H
R
Site 262
T2067
T
T
P
P
T
T
A
T
P
I
R
H
R
P
R
Site 263
Y2076
I
R
H
R
P
R
P
Y
P
P
N
V
G
E
E
Site 264
Y2096
I
P
R
E
D
V
D
Y
H
L
Y
P
H
G
P
Site 265
Y2099
E
D
V
D
Y
H
L
Y
P
H
G
P
G
L
N
Site 266
S2110
P
G
L
N
P
N
A
S
T
G
Q
E
A
L
S
Site 267
S2117
S
T
G
Q
E
A
L
S
Q
T
T
I
S
W
A
Site 268
T2129
S
W
A
P
F
Q
D
T
S
E
Y
I
I
S
C
Site 269
Y2132
P
F
Q
D
T
S
E
Y
I
I
S
C
H
P
V
Site 270
S2154
Q
F
R
V
P
G
T
S
T
S
A
T
L
T
G
Site 271
S2156
R
V
P
G
T
S
T
S
A
T
L
T
G
L
T
Site 272
T2158
P
G
T
S
T
S
A
T
L
T
G
L
T
R
G
Site 273
T2160
T
S
T
S
A
T
L
T
G
L
T
R
G
A
T
Site 274
T2189
K
V
R
E
E
V
V
T
V
G
N
S
V
N
E
Site 275
S2205
L
N
Q
P
T
D
D
S
C
F
D
P
Y
T
V
Site 276
Y2210
D
D
S
C
F
D
P
Y
T
V
S
H
Y
A
V
Site 277
S2225
G
D
E
W
E
R
M
S
E
S
G
F
K
L
L
Site 278
S2227
E
W
E
R
M
S
E
S
G
F
K
L
L
C
Q
Site 279
Y2258
C
H
D
N
G
V
N
Y
K
I
G
E
K
W
D
Site 280
Y2296
D
P
H
E
A
T
C
Y
D
D
G
K
T
Y
H
Site 281
Y2302
C
Y
D
D
G
K
T
Y
H
V
G
E
Q
W
Q
Site 282
Y2312
G
E
Q
W
Q
K
E
Y
L
G
A
I
C
S
C
Site 283
S2341
R
R
P
G
G
E
P
S
P
E
G
T
T
G
Q
Site 284
T2345
G
E
P
S
P
E
G
T
T
G
Q
S
Y
N
Q
Site 285
Y2350
E
G
T
T
G
Q
S
Y
N
Q
Y
S
Q
R
Y
Site 286
Y2353
T
G
Q
S
Y
N
Q
Y
S
Q
R
Y
H
Q
R
Site 287
S2354
G
Q
S
Y
N
Q
Y
S
Q
R
Y
H
Q
R
T
Site 288
T2363
R
Y
H
Q
R
T
N
T
N
V
N
C
P
I
E
Site 289
S2384
V
Q
A
D
R
E
D
S
R
E
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation