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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GC
Full Name:
Vitamin D-binding protein
Alias:
Gc-globulin;Group-specific component
Type:
Mass (Da):
52964
Number AA:
474
UniProt ID:
P02774
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y23
A
L
E
R
G
R
D
Y
E
K
N
K
V
C
K
Site 2
S33
N
K
V
C
K
E
F
S
H
L
G
K
E
D
F
Site 3
S44
K
E
D
F
T
S
L
S
L
V
L
Y
S
R
K
Site 4
Y48
T
S
L
S
L
V
L
Y
S
R
K
F
P
S
G
Site 5
T56
S
R
K
F
P
S
G
T
F
E
Q
V
S
Q
L
Site 6
Y84
E
G
A
D
P
D
C
Y
D
T
R
T
S
A
L
Site 7
T86
A
D
P
D
C
Y
D
T
R
T
S
A
L
S
A
Site 8
T88
P
D
C
Y
D
T
R
T
S
A
L
S
A
K
S
Site 9
S89
D
C
Y
D
T
R
T
S
A
L
S
A
K
S
C
Site 10
S92
D
T
R
T
S
A
L
S
A
K
S
C
E
S
N
Site 11
S95
T
S
A
L
S
A
K
S
C
E
S
N
S
P
F
Site 12
S98
L
S
A
K
S
C
E
S
N
S
P
F
P
V
H
Site 13
S100
A
K
S
C
E
S
N
S
P
F
P
V
H
P
G
Site 14
T108
P
F
P
V
H
P
G
T
A
E
C
C
T
K
E
Site 15
Y136
Q
P
Q
E
F
P
T
Y
V
E
P
T
N
D
E
Site 16
S173
N
Y
G
Q
A
P
L
S
L
L
V
S
Y
T
K
Site 17
S184
S
Y
T
K
S
Y
L
S
M
V
G
S
C
C
T
Site 18
S210
R
L
Q
L
K
H
L
S
L
L
T
T
L
S
N
Site 19
S221
T
L
S
N
R
V
C
S
Q
Y
A
A
Y
G
E
Site 20
Y223
S
N
R
V
C
S
Q
Y
A
A
Y
G
E
K
K
Site 21
S231
A
A
Y
G
E
K
K
S
R
L
S
N
L
I
K
Site 22
S234
G
E
K
K
S
R
L
S
N
L
I
K
L
A
Q
Site 23
S263
E
D
I
T
N
I
L
S
K
C
C
E
S
A
S
Site 24
S270
S
K
C
C
E
S
A
S
E
D
C
M
A
K
E
Site 25
S290
V
K
L
C
D
N
L
S
T
K
N
S
K
F
E
Site 26
Y346
N
T
K
V
M
D
K
Y
T
F
E
L
S
R
R
Site 27
T347
T
K
V
M
D
K
Y
T
F
E
L
S
R
R
T
Site 28
S351
D
K
Y
T
F
E
L
S
R
R
T
H
L
P
E
Site 29
T354
T
F
E
L
S
R
R
T
H
L
P
E
V
F
L
Site 30
S397
P
L
L
K
K
E
L
S
S
F
I
D
K
G
Q
Site 31
S398
L
L
K
K
E
L
S
S
F
I
D
K
G
Q
E
Site 32
Y410
G
Q
E
L
C
A
D
Y
S
E
N
T
F
T
E
Site 33
T416
D
Y
S
E
N
T
F
T
E
Y
K
K
K
L
A
Site 34
T434
K
A
K
L
P
D
A
T
P
K
E
L
A
K
L
Site 35
S446
A
K
L
V
N
K
R
S
D
F
A
S
N
C
C
Site 36
S450
N
K
R
S
D
F
A
S
N
C
C
S
I
N
S
Site 37
S457
S
N
C
C
S
I
N
S
P
P
L
Y
C
D
S
Site 38
Y461
S
I
N
S
P
P
L
Y
C
D
S
E
I
D
A
Site 39
S464
S
P
P
L
Y
C
D
S
E
I
D
A
E
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation