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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HPX
Full Name:
Hemopexin
Alias:
Beta-1B-glycoprotein; HEMO
Type:
Uncharacterized protein
Mass (Da):
51676
Number AA:
462
UniProt ID:
P02790
International Prot ID:
IPI00022488
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0015232
GO:0005506
PhosphoSite+
KinaseNET
Biological Process:
GO:0006879
GO:0015886
GO:0044419
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
A
T
P
L
P
P
T
S
A
H
G
N
V
A
E
Site 2
T47
T
K
P
D
P
D
V
T
E
R
C
S
D
G
W
Site 3
S51
P
D
V
T
E
R
C
S
D
G
W
S
F
D
A
Site 4
S55
E
R
C
S
D
G
W
S
F
D
A
T
T
L
D
Site 5
T59
D
G
W
S
F
D
A
T
T
L
D
D
N
G
T
Site 6
T66
T
T
L
D
D
N
G
T
M
L
F
F
K
G
E
Site 7
S95
E
R
W
K
N
F
P
S
P
V
D
A
A
F
R
Site 8
S107
A
F
R
Q
G
H
N
S
V
F
L
I
K
G
D
Site 9
Y119
K
G
D
K
V
W
V
Y
P
P
E
K
K
E
K
Site 10
Y128
P
E
K
K
E
K
G
Y
P
K
L
L
Q
D
E
Site 11
S141
D
E
F
P
G
I
P
S
P
L
D
A
A
V
E
Site 12
T174
E
W
F
W
D
L
A
T
G
T
M
K
E
R
S
Site 13
S190
P
A
V
G
N
C
S
S
A
L
R
W
L
G
R
Site 14
Y198
A
L
R
W
L
G
R
Y
Y
C
F
Q
G
N
Q
Site 15
Y220
R
G
E
V
P
P
R
Y
P
R
D
V
R
D
Y
Site 16
Y227
Y
P
R
D
V
R
D
Y
F
M
P
C
P
G
R
Site 17
T242
G
H
G
H
R
N
G
T
G
H
G
N
S
T
H
Site 18
S247
N
G
T
G
H
G
N
S
T
H
H
G
P
E
Y
Site 19
Y254
S
T
H
H
G
P
E
Y
M
R
C
S
P
H
L
Site 20
S258
G
P
E
Y
M
R
C
S
P
H
L
V
L
S
A
Site 21
S264
C
S
P
H
L
V
L
S
A
L
T
S
D
N
H
Site 22
T274
T
S
D
N
H
G
A
T
Y
A
F
S
G
T
H
Site 23
Y275
S
D
N
H
G
A
T
Y
A
F
S
G
T
H
Y
Site 24
Y282
Y
A
F
S
G
T
H
Y
W
R
L
D
T
S
R
Site 25
S313
S
A
V
D
A
A
F
S
W
E
E
K
L
Y
L
Site 26
Y319
F
S
W
E
E
K
L
Y
L
V
Q
G
T
Q
V
Site 27
Y327
L
V
Q
G
T
Q
V
Y
V
F
L
T
K
G
G
Site 28
Y335
V
F
L
T
K
G
G
Y
T
L
V
S
G
Y
P
Site 29
S339
K
G
G
Y
T
L
V
S
G
Y
P
K
R
L
E
Site 30
Y341
G
Y
T
L
V
S
G
Y
P
K
R
L
E
K
E
Site 31
T351
R
L
E
K
E
V
G
T
P
H
G
I
I
L
D
Site 32
T394
S
G
A
Q
A
T
W
T
E
L
P
W
P
H
E
Site 33
S412
G
A
L
C
M
E
K
S
L
G
P
N
S
C
S
Site 34
S417
E
K
S
L
G
P
N
S
C
S
A
N
G
P
G
Site 35
S419
S
L
G
P
N
S
C
S
A
N
G
P
G
L
Y
Site 36
Y426
S
A
N
G
P
G
L
Y
L
I
H
G
P
N
L
Site 37
Y434
L
I
H
G
P
N
L
Y
C
Y
S
D
V
E
K
Site 38
Y436
H
G
P
N
L
Y
C
Y
S
D
V
E
K
L
N
Site 39
S437
G
P
N
L
Y
C
Y
S
D
V
E
K
L
N
A
Site 40
S456
P
Q
P
Q
N
V
T
S
L
L
G
C
T
H
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation