PhosphoNET

           
Protein Info 
   
Short Name:  MT-ND4
Full Name:  NADH-ubiquinone oxidoreductase chain 4
Alias:  NADH dehydrogenase subunit 4
Type: 
Mass (Da):  51563
Number AA:  459
UniProt ID:  P03905
International Prot ID:  IPI00008495
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005739  GO:0005746  GO:0005747 Uniprot OncoNet
Molecular Function:  GO:0003824  GO:0003954  GO:0008137 PhosphoSite+ KinaseNET
Biological Process:  GO:0006091  GO:0006118  GO:0006120 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T15TIMLLPLTWLSKKHM
Site 2S51QINNNLFSCSPTFSS
Site 3S53NNNLFSCSPTFSSDP
Site 4T55NLFSCSPTFSSDPLT
Site 5S57FSCSPTFSSDPLTTP
Site 6S58SCSPTFSSDPLTTPL
Site 7S80LPLTIMASQRHLSSE
Site 8S85MASQRHLSSEPLSRK
Site 9S86ASQRHLSSEPLSRKK
Site 10S90HLSSEPLSRKKLYLS
Site 11S187TLTAQELSNSWANNL
Site 12Y241VLLKLGGYGMMRLTL
Site 13T247GYGMMRLTLILNPLT
Site 14T254TLILNPLTKHMAYPF
Site 15S284LRQTDLKSLIAYSSI
Site 16S290KSLIAYSSISHMALV
Site 17S332LLFCLANSNYERTHS
Site 18Y334FCLANSNYERTHSRI
Site 19S339SNYERTHSRIMILSQ
Site 20S429HINNMKPSFTRENTL
Site 21T435PSFTRENTLMFMHLS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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