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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MMP1
Full Name:
Interstitial collagenase
Alias:
Fibroblast collagenase;Matrix metalloproteinase-1
Type:
Mass (Da):
54007
Number AA:
469
UniProt ID:
P03956
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
V
S
H
S
F
P
A
T
L
E
T
Q
E
Q
D
Site 2
Y37
D
V
D
L
V
Q
K
Y
L
E
K
Y
Y
N
L
Site 3
Y41
V
Q
K
Y
L
E
K
Y
Y
N
L
K
N
D
G
Site 4
S57
Q
V
E
K
R
R
N
S
G
P
V
V
E
K
L
Site 5
T83
T
G
K
P
D
A
E
T
L
K
V
M
K
Q
P
Site 6
Y121
L
T
Y
R
I
E
N
Y
T
P
D
L
P
R
A
Site 7
T122
T
Y
R
I
E
N
Y
T
P
D
L
P
R
A
D
Site 8
S142
E
K
A
F
Q
L
W
S
N
V
T
P
L
T
F
Site 9
T148
W
S
N
V
T
P
L
T
F
T
K
V
S
E
G
Site 10
S153
P
L
T
F
T
K
V
S
E
G
Q
A
D
I
M
Site 11
S162
G
Q
A
D
I
M
I
S
F
V
R
G
D
H
R
Site 12
S172
R
G
D
H
R
D
N
S
P
F
D
G
P
G
G
Site 13
Y210
W
T
N
N
F
R
E
Y
N
L
H
R
V
A
A
Site 14
S223
A
A
H
E
L
G
H
S
L
G
L
S
H
S
T
Site 15
Y240
G
A
L
M
Y
P
S
Y
T
F
S
G
D
V
Q
Site 16
S243
M
Y
P
S
Y
T
F
S
G
D
V
Q
L
A
Q
Site 17
Y260
I
D
G
I
Q
A
I
Y
G
R
S
Q
N
P
V
Site 18
S263
I
Q
A
I
Y
G
R
S
Q
N
P
V
Q
P
I
Site 19
T274
V
Q
P
I
G
P
Q
T
P
K
A
C
D
S
K
Site 20
Y309
Y
M
R
T
N
P
F
Y
P
E
V
E
L
N
F
Site 21
Y348
R
F
F
K
G
N
K
Y
W
A
V
Q
G
Q
N
Site 22
Y360
G
Q
N
V
L
H
G
Y
P
K
D
I
Y
S
S
Site 23
Y365
H
G
Y
P
K
D
I
Y
S
S
F
G
F
P
R
Site 24
S366
G
Y
P
K
D
I
Y
S
S
F
G
F
P
R
T
Site 25
S367
Y
P
K
D
I
Y
S
S
F
G
F
P
R
T
V
Site 26
T373
S
S
F
G
F
P
R
T
V
K
H
I
D
A
A
Site 27
Y390
E
E
N
T
G
K
T
Y
F
F
V
A
N
K
Y
Site 28
Y397
Y
F
F
V
A
N
K
Y
W
R
Y
D
E
Y
K
Site 29
Y400
V
A
N
K
Y
W
R
Y
D
E
Y
K
R
S
M
Site 30
Y403
K
Y
W
R
Y
D
E
Y
K
R
S
M
D
P
G
Site 31
S406
R
Y
D
E
Y
K
R
S
M
D
P
G
Y
P
K
Site 32
Y411
K
R
S
M
D
P
G
Y
P
K
M
I
A
H
D
Site 33
Y445
F
F
H
G
T
R
Q
Y
K
F
D
P
K
T
K
Site 34
T451
Q
Y
K
F
D
P
K
T
K
R
I
L
T
L
Q
Site 35
T456
P
K
T
K
R
I
L
T
L
Q
K
A
N
S
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation