PhosphoNET

           
Protein Info 
   
Short Name:  C4BPA
Full Name:  C4b-binding protein alpha chain
Alias:  Proline-rich protein
Type: 
Mass (Da):  67033
Number AA:  597
UniProt ID:  P04003
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T6__MHPPKTPSGALHR
Site 2T65FAAPMDITLTETRFK
Site 3T67APMDITLTETRFKTG
Site 4T73LTETRFKTGTTLKYT
Site 5T75ETRFKTGTTLKYTCL
Site 6Y79KTGTTLKYTCLPGYV
Site 7T80TGTTLKYTCLPGYVR
Site 8Y85KYTCLPGYVRSHSTQ
Site 9S88CLPGYVRSHSTQTLT
Site 10S90PGYVRSHSTQTLTCN
Site 11T95SHSTQTLTCNSDGEW
Site 12T128NGQVEIKTDLSFGSQ
Site 13S131VEIKTDLSFGSQIEF
Site 14S134KTDLSFGSQIEFSCS
Site 15S187DIRNGRHSGEENFYA
Site 16Y193HSGEENFYAYGFSVT
Site 17S202YGFSVTYSCDPRFSL
Site 18S208YSCDPRFSLLGHASI
Site 19T218GHASISCTVENETIG
Site 20S230TIGVWRPSPPTCEKI
Site 21T233VWRPSPPTCEKITCR
Site 22S245TCRKPDVSHGEMVSG
Site 23S251VSHGEMVSGFGPIYN
Site 24Y259GFGPIYNYKDTIVFK
Site 25S290ADSKWNPSPPACEPN
Site 26S298PPACEPNSCINLPDI
Site 27S309LPDIPHASWETYPRP
Site 28Y313PHASWETYPRPTKED
Site 29T317WETYPRPTKEDVYVV
Site 30Y322RPTKEDVYVVGTVLR
Site 31Y330VVGTVLRYRCHPGYK
Site 32Y336RYRCHPGYKPTTDEP
Site 33T340HPGYKPTTDEPTTVI
Site 34T345PTTDEPTTVICQKNL
Site 35Y357KNLRWTPYQGCEALC
Site 36T376KLNNGEITQHRKSRP
Site 37Y389RPANHCVYFYGDEIS
Site 38Y391ANHCVYFYGDEISFS
Site 39S398YGDEISFSCHETSRF
Site 40T414AICQGDGTWSPRTPS
Site 41S416CQGDGTWSPRTPSCG
Site 42T419DGTWSPRTPSCGDIC
Site 43Y437PKIAHGHYKQSSSYS
Site 44S440AHGHYKQSSSYSFFK
Site 45S441HGHYKQSSSYSFFKE
Site 46S442GHYKQSSSYSFFKEE
Site 47S444YKQSSSYSFFKEEII
Site 48Y452FFKEEIIYECDKGYI
Site 49Y458IYECDKGYILVGQAK
Site 50S467LVGQAKLSCSYSHWS
Site 51S469GQAKLSCSYSHWSAP
Site 52S471AKLSCSYSHWSAPAP
Site 53S495ELVNGRLSVDKDQYV
Site 54Y501LSVDKDQYVEPENVT
Site 55Y515TIQCDSGYGVVGPQS
Site 56S522YGVVGPQSITCSGNR
Site 57T530ITCSGNRTWYPEVPK
Site 58Y532CSGNRTWYPEVPKCE
Site 59T542VPKCEWETPEGCEQV
Site 60T551EGCEQVLTGKRLMQC
Site 61S587QLELQRDSARQSTLD
Site 62S591QRDSARQSTLDKEL_
Site 63T592RDSARQSTLDKEL__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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