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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
N-Myc
Full Name:
N-myc proto-oncogene protein
Alias:
BHLHe37; MYCN; NMYC; N-myc; NMYC1; V-myc myelocytomatosis viral related oncogene, neuroblastoma derived; V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Type:
Transcription protein
Mass (Da):
49561
Number AA:
464
UniProt ID:
P04198
International Prot ID:
IPI00022372
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006357
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
P
S
C
S
T
S
T
M
P
Site 2
S5
_
_
_
M
P
S
C
S
T
S
T
M
P
G
M
Site 3
T6
_
_
M
P
S
C
S
T
S
T
M
P
G
M
I
Site 4
S7
_
M
P
S
C
S
T
S
T
M
P
G
M
I
C
Site 5
T8
M
P
S
C
S
T
S
T
M
P
G
M
I
C
K
Site 6
S23
N
P
D
L
E
F
D
S
L
Q
P
C
F
Y
P
Site 7
Y29
D
S
L
Q
P
C
F
Y
P
D
E
D
D
F
Y
Site 8
Y36
Y
P
D
E
D
D
F
Y
F
G
G
P
D
S
T
Site 9
S42
F
Y
F
G
G
P
D
S
T
P
P
G
E
D
I
Site 10
T43
Y
F
G
G
P
D
S
T
P
P
G
E
D
I
W
Site 11
T58
K
K
F
E
L
L
P
T
P
P
L
S
P
S
R
Site 12
S62
L
L
P
T
P
P
L
S
P
S
R
G
F
A
E
Site 13
S64
P
T
P
P
L
S
P
S
R
G
F
A
E
H
S
Site 14
S71
S
R
G
F
A
E
H
S
S
E
P
P
S
W
V
Site 15
S72
R
G
F
A
E
H
S
S
E
P
P
S
W
V
T
Site 16
S76
E
H
S
S
E
P
P
S
W
V
T
E
M
L
L
Site 17
S90
L
E
N
E
L
W
G
S
P
A
E
E
D
A
F
Site 18
S121
D
C
M
W
S
G
F
S
A
R
E
K
L
E
R
Site 19
S131
E
K
L
E
R
A
V
S
E
K
L
Q
H
G
R
Site 20
S145
R
G
P
P
T
A
G
S
T
A
Q
S
P
G
A
Site 21
S149
T
A
G
S
T
A
Q
S
P
G
A
G
A
A
S
Site 22
S156
S
P
G
A
G
A
A
S
P
A
G
R
G
H
G
Site 23
T244
P
R
P
G
G
R
Q
T
S
G
G
D
H
K
A
Site 24
S245
R
P
G
G
R
Q
T
S
G
G
D
H
K
A
L
Site 25
S253
G
G
D
H
K
A
L
S
T
S
G
E
D
T
L
Site 26
S255
D
H
K
A
L
S
T
S
G
E
D
T
L
S
D
Site 27
T259
L
S
T
S
G
E
D
T
L
S
D
S
D
D
E
Site 28
S261
T
S
G
E
D
T
L
S
D
S
D
D
E
D
D
Site 29
S263
G
E
D
T
L
S
D
S
D
D
E
D
D
E
E
Site 30
T281
E
E
E
I
D
V
V
T
V
E
K
R
R
S
S
Site 31
S287
V
T
V
E
K
R
R
S
S
S
N
T
K
A
V
Site 32
S288
T
V
E
K
R
R
S
S
S
N
T
K
A
V
T
Site 33
S289
V
E
K
R
R
S
S
S
N
T
K
A
V
T
T
Site 34
T291
K
R
R
S
S
S
N
T
K
A
V
T
T
F
T
Site 35
T296
S
N
T
K
A
V
T
T
F
T
I
T
V
R
P
Site 36
S315
L
G
P
G
R
A
Q
S
S
E
L
I
L
K
R
Site 37
S316
G
P
G
R
A
Q
S
S
E
L
I
L
K
R
C
Site 38
Y332
P
I
H
Q
Q
H
N
Y
A
A
P
S
P
Y
V
Site 39
S336
Q
H
N
Y
A
A
P
S
P
Y
V
E
S
E
D
Site 40
Y338
N
Y
A
A
P
S
P
Y
V
E
S
E
D
A
P
Site 41
S341
A
P
S
P
Y
V
E
S
E
D
A
P
P
Q
K
Site 42
S352
P
P
Q
K
K
I
K
S
E
A
S
P
R
P
L
Site 43
S355
K
K
I
K
S
E
A
S
P
R
P
L
K
S
V
Site 44
S361
A
S
P
R
P
L
K
S
V
I
P
P
K
A
K
Site 45
S369
V
I
P
P
K
A
K
S
L
S
P
R
N
S
D
Site 46
S371
P
P
K
A
K
S
L
S
P
R
N
S
D
S
E
Site 47
S375
K
S
L
S
P
R
N
S
D
S
E
D
S
E
R
Site 48
S377
L
S
P
R
N
S
D
S
E
D
S
E
R
R
R
Site 49
S380
R
N
S
D
S
E
D
S
E
R
R
R
N
H
N
Site 50
S399
Q
R
R
N
D
L
R
S
S
F
L
T
L
R
D
Site 51
S400
R
R
N
D
L
R
S
S
F
L
T
L
R
D
H
Site 52
T403
D
L
R
S
S
F
L
T
L
R
D
H
V
P
E
Site 53
T427
V
V
I
L
K
K
A
T
E
Y
V
H
S
L
Q
Site 54
Y429
I
L
K
K
A
T
E
Y
V
H
S
L
Q
A
E
Site 55
S432
K
A
T
E
Y
V
H
S
L
Q
A
E
E
H
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation