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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CD74
Full Name:
HLA class II histocompatibility antigen gamma chain
Alias:
CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG; Gamma chain of class II antigens; HG2A; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia antigen-associated invariant chain; Ia-associated invariant chain; Ii; MHC HLA-DR gamma chain; P33
Type:
Mass (Da):
33516
Number AA:
296
UniProt ID:
P04233
International Prot ID:
IPI00022933
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0042289
GO:0019955
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0019883
GO:0008283
GO:0016064
Phosida
TranscriptoNet
STRING
Kinexus Products
HLA class II histocompatibility antigen gamma chain pan-specific antibody AB-NN229-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN229-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
H
R
R
R
S
R
S
C
R
E
D
Q
K
P
Site 2
S25
D
D
Q
R
D
L
I
S
N
N
E
Q
L
P
M
Site 3
S42
R
R
P
G
A
P
E
S
K
C
S
R
G
A
L
Site 4
S45
G
A
P
E
S
K
C
S
R
G
A
L
Y
T
G
Site 5
Y69
A
G
Q
A
T
T
A
Y
F
L
Y
Q
Q
Q
G
Site 6
Y72
A
T
T
A
Y
F
L
Y
Q
Q
Q
G
R
L
D
Site 7
T132
Q
G
P
M
Q
N
A
T
K
Y
G
N
M
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation