PhosphoNET

           
Protein Info 
   
Short Name:  KRT1
Full Name:  Keratin, type II cytoskeletal 1
Alias:  67 kDa cytokeratin; CK1; CK-1; Cytokeratin-1; EHK1; Hair alpha protein; K2C1; Keratin 1; Keratin-1; KRT1A; KRTA
Type:  Cytoskeletal protein
Mass (Da):  66039
Number AA:  644
UniProt ID:  P04264
International Prot ID:  IPI00220327
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005886  GO:0016020   Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0004872  GO:0005200 PhosphoSite+ KinaseNET
Biological Process:  GO:0001867  GO:0008544  GO:0042730 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MSRQFSSRSGYRS
Site 2S7_MSRQFSSRSGYRSG
Site 3S9SRQFSSRSGYRSGGG
Site 4Y11QFSSRSGYRSGGGFS
Site 5S13SSRSGYRSGGGFSSG
Site 6S18YRSGGGFSSGSAGII
Site 7S19RSGGGFSSGSAGIIN
Site 8S21GGGFSSGSAGIINYQ
Site 9Y27GSAGIINYQRRTTSS
Site 10T31IINYQRRTTSSSTRR
Site 11T32INYQRRTTSSSTRRS
Site 12S33NYQRRTTSSSTRRSG
Site 13S34YQRRTTSSSTRRSGG
Site 14S35QRRTTSSSTRRSGGG
Site 15T36RRTTSSSTRRSGGGG
Site 16S39TSSSTRRSGGGGGRF
Site 17S47GGGGGRFSSCGGGGG
Site 18S48GGGGRFSSCGGGGGS
Site 19S55SCGGGGGSFGAGGGF
Site 20S64GAGGGFGSRSLVNLG
Site 21S66GGGFGSRSLVNLGGS
Site 22S73SLVNLGGSKSISISV
Site 23S77LGGSKSISISVARGG
Site 24S79GSKSISISVARGGGR
Site 25S88ARGGGRGSGFGGGYG
Site 26Y94GSGFGGGYGGGGFGG
Site 27Y139GGFGGGGYGGGYGPV
Site 28Y143GGGYGGGYGPVCPPG
Site 29T156PGGIQEVTINQSLLQ
Site 30S178PEIQKVKSREREQIK
Site 31S186REREQIKSLNNQFAS
Site 32S193SLNNQFASFIDKVRF
Site 33T220ELLQQVDTSTRTHNL
Site 34S221LLQQVDTSTRTHNLE
Site 35Y230RTHNLEPYFESFINN
Site 36S233NLEPYFESFINNLRR
Site 37S247RRVDQLKSDQSRLDS
Site 38S250DQLKSDQSRLDSELK
Site 39S254SDQSRLDSELKNMQD
Site 40Y266MQDMVEDYRNKYEDE
Site 41Y270VEDYRNKYEDEINKR
Site 42Y295KKDVDGAYMTKVDLQ
Site 43S324ALYQAELSQMQTQIS
Site 44T328AELSQMQTQISETNV
Site 45S338SETNVILSMDNNRSL
Site 46S344LSMDNNRSLDLDSII
Site 47S349NRSLDLDSIIAEVKA
Site 48Y358IAEVKAQYEDIAQKS
Site 49S365YEDIAQKSKAEAESL
Site 50S371KSKAEAESLYQSKYE
Site 51Y373KAEAESLYQSKYEEL
Site 52S375EAESLYQSKYEELQI
Site 53Y377ESLYQSKYEELQITA
Site 54T383KYEELQITAGRHGDS
Site 55S390TAGRHGDSVRNSKIE
Site 56S394HGDSVRNSKIEISEL
Site 57S399RNSKIEISELNRVIQ
Site 58S410RVIQRLRSEIDNVKK
Site 59S427SNLQQSISDAEQRGE
Site 60Y465LARLLRDYQELMNTK
Site 61T471DYQELMNTKLALDLE
Site 62Y482LDLEIATYRTLLEGE
Site 63S491TLLEGEESRMSGECA
Site 64S494EGEESRMSGECAPNV
Site 65S502GECAPNVSVSVSTSH
Site 66S504CAPNVSVSVSTSHTT
Site 67S506PNVSVSVSTSHTTIS
Site 68T507NVSVSVSTSHTTISG
Site 69T510VSVSTSHTTISGGGS
Site 70T511SVSTSHTTISGGGSR
Site 71S513STSHTTISGGGSRGG
Site 72S517TTISGGGSRGGGGGG
Site 73Y525RGGGGGGYGSGGSSY
Site 74S527GGGGGYGSGGSSYGS
Site 75S530GGYGSGGSSYGSGGG
Site 76S531GYGSGGSSYGSGGGS
Site 77Y532YGSGGSSYGSGGGSY
Site 78S534SGGSSYGSGGGSYGS
Site 79S538SYGSGGGSYGSGGGG
Site 80Y539YGSGGGSYGSGGGGG
Site 81S541SGGGSYGSGGGGGGG
Site 82S551GGGGGRGSYGSGGSS
Site 83Y552GGGGRGSYGSGGSSY
Site 84S554GGRGSYGSGGSSYGS
Site 85S557GSYGSGGSSYGSGGG
Site 86S558SYGSGGSSYGSGGGS
Site 87S568SGGGSYGSGGGGGGH
Site 88S577GGGGGHGSYGSGSSS
Site 89Y578GGGGHGSYGSGSSSG
Site 90S580GGHGSYGSGSSSGGY
Site 91S582HGSYGSGSSSGGYRG
Site 92S584SYGSGSSSGGYRGGS
Site 93Y587SGSSSGGYRGGSGGG
Site 94S591SGGYRGGSGGGGGGS
Site 95S598SGGGGGGSSGGRGSG
Site 96S599GGGGGGSSGGRGSGG
Site 97S604GSSGGRGSGGGSSGG
Site 98S608GRGSGGGSSGGSIGG
Site 99S609RGSGGGSSGGSIGGR
Site 100S612GGGSSGGSIGGRGSS
Site 101S618GSIGGRGSSSGGVKS
Site 102S619SIGGRGSSSGGVKSS
Site 103S620IGGRGSSSGGVKSSG
Site 104S625SSSGGVKSSGGSSSV
Site 105S626SSGGVKSSGGSSSVK
Site 106S629GVKSSGGSSSVKFVS
Site 107S630VKSSGGSSSVKFVST
Site 108S631KSSGGSSSVKFVSTT
Site 109S636SSSVKFVSTTYSGVT
Site 110T638SVKFVSTTYSGVTR_
Site 111Y639VKFVSTTYSGVTR__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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