PhosphoNET

           
Protein Info 
   
Short Name:  SHBG
Full Name:  Sex hormone-binding globulin
Alias:  Sex steroid-binding protein;Testis-specific androgen-binding protein;Testosterone-estradiol-binding globulin;Testosterone-estrogen-binding globulin
Type: 
Mass (Da):  43779
Number AA:  402
UniProt ID:  P04278
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T36ALRPVLPTQSAHDPP
Site 2S38RPVLPTQSAHDPPAV
Site 3S48DPPAVHLSNGPGQEP
Site 4T67TFDLTKITKTSSSFE
Site 5T69DLTKITKTSSSFEVR
Site 6S72KITKTSSSFEVRTWD
Site 7T77SSSFEVRTWDPEGVI
Site 8T117HNHWAQLTVGAGPRL
Site 9S157VLRLRQVSGPLTSKR
Site 10T161RQVSGPLTSKRHPIM
Site 11S162QVSGPLTSKRHPIMR
Site 12S198DGCLRRDSWLDKQAE
Site 13S207LDKQAEISASAPTSL
Site 14S209KQAEISASAPTSLRS
Site 15S213ISASAPTSLRSCDVE
Site 16S216SAPTSLRSCDVESNP
Site 17S221LRSCDVESNPGIFLP
Site 18T231GIFLPPGTQAEFNLR
Site 19T270GHLLALGTPENPSWL
Site 20S278PENPSWLSLHLQDQK
Site 21S289QDQKVVLSSGSGPGL
Site 22S290DQKVVLSSGSGPGLD
Site 23S318SMSRVVLSQGSKMKA
Site 24S357GALPGEDSSTSFCLN
Site 25S358ALPGEDSSTSFCLNG
Site 26T359LPGEDSSTSFCLNGL
Site 27S360PGEDSSTSFCLNGLW
Site 28S393WTHSCPQSPGNGTDA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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