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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GAPDH
Full Name:
Glyceraldehyde-3-phosphate dehydrogenase
Alias:
EC 1.2.1.12; G3P; G3P2; GAPD; Glyceraldehyde-3-phosphate dehydrogenase
Type:
Mitochondrial; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Oxidoreductase; EC 1.2.1.12
Mass (Da):
36053
Number AA:
335
UniProt ID:
P04406
International Prot ID:
IPI00219018
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0051287
GO:0004365
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006096
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T19
G
R
I
G
R
L
V
T
R
A
A
F
N
S
G
Site 2
S25
V
T
R
A
A
F
N
S
G
K
V
D
I
V
A
Site 3
Y42
D
P
F
I
D
L
N
Y
M
V
Y
M
F
Q
Y
Site 4
Y45
I
D
L
N
Y
M
V
Y
M
F
Q
Y
D
S
T
Site 5
Y49
Y
M
V
Y
M
F
Q
Y
D
S
T
H
G
K
F
Site 6
S51
V
Y
M
F
Q
Y
D
S
T
H
G
K
F
H
G
Site 7
T52
Y
M
F
Q
Y
D
S
T
H
G
K
F
H
G
T
Site 8
T59
T
H
G
K
F
H
G
T
V
K
A
E
N
G
K
Site 9
T75
V
I
N
G
N
P
I
T
I
F
Q
E
R
D
P
Site 10
S83
I
F
Q
E
R
D
P
S
K
I
K
W
G
D
A
Site 11
Y94
W
G
D
A
G
A
E
Y
V
V
E
S
T
G
V
Site 12
T99
A
E
Y
V
V
E
S
T
G
V
F
T
T
M
E
Site 13
T103
V
E
S
T
G
V
F
T
T
M
E
K
A
G
A
Site 14
T104
E
S
T
G
V
F
T
T
M
E
K
A
G
A
H
Site 15
Y140
M
G
V
N
H
E
K
Y
D
N
S
L
K
I
I
Site 16
S143
N
H
E
K
Y
D
N
S
L
K
I
I
S
N
A
Site 17
S148
D
N
S
L
K
I
I
S
N
A
S
C
T
T
N
Site 18
S151
L
K
I
I
S
N
A
S
C
T
T
N
C
L
A
Site 19
T153
I
I
S
N
A
S
C
T
T
N
C
L
A
P
L
Site 20
T154
I
S
N
A
S
C
T
T
N
C
L
A
P
L
A
Site 21
T176
G
I
V
E
G
L
M
T
T
V
H
A
I
T
A
Site 22
T177
I
V
E
G
L
M
T
T
V
H
A
I
T
A
T
Site 23
T182
M
T
T
V
H
A
I
T
A
T
Q
K
T
V
D
Site 24
T184
T
V
H
A
I
T
A
T
Q
K
T
V
D
G
P
Site 25
T187
A
I
T
A
T
Q
K
T
V
D
G
P
S
G
K
Site 26
S192
Q
K
T
V
D
G
P
S
G
K
L
W
R
D
G
Site 27
S210
L
Q
N
I
I
P
A
S
T
G
A
A
K
A
V
Site 28
T211
Q
N
I
I
P
A
S
T
G
A
A
K
A
V
G
Site 29
T229
P
E
L
N
G
K
L
T
G
M
A
F
R
V
P
Site 30
T237
G
M
A
F
R
V
P
T
A
N
V
S
V
V
D
Site 31
S241
R
V
P
T
A
N
V
S
V
V
D
L
T
C
R
Site 32
T246
N
V
S
V
V
D
L
T
C
R
L
E
K
P
A
Site 33
Y255
R
L
E
K
P
A
K
Y
D
D
I
K
K
V
V
Site 34
S266
K
K
V
V
K
Q
A
S
E
G
P
L
K
G
I
Site 35
S284
T
E
H
Q
V
V
S
S
D
F
N
S
D
T
H
Site 36
S288
V
V
S
S
D
F
N
S
D
T
H
S
S
T
F
Site 37
T290
S
S
D
F
N
S
D
T
H
S
S
T
F
D
A
Site 38
S292
D
F
N
S
D
T
H
S
S
T
F
D
A
G
A
Site 39
S293
F
N
S
D
T
H
S
S
T
F
D
A
G
A
G
Site 40
T294
N
S
D
T
H
S
S
T
F
D
A
G
A
G
I
Site 41
S312
D
H
F
V
K
L
I
S
W
Y
D
N
E
F
G
Site 42
Y314
F
V
K
L
I
S
W
Y
D
N
E
F
G
Y
S
Site 43
Y320
W
Y
D
N
E
F
G
Y
S
N
R
V
V
D
L
Site 44
S321
Y
D
N
E
F
G
Y
S
N
R
V
V
D
L
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation