PhosphoNET

           
Protein Info 
   
Short Name:  CAPNS1
Full Name:  Calpain small subunit 1
Alias:  30K; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; Calpain regulatory subunit; Calpain, small subunit 1; CANP; CANP small subunit; CANPS; CAPN4; CAPN4, CAPNS; CDPS; CPNS1; CSS1
Type:  Protease
Mass (Da):  28316
Number AA:  268
UniProt ID:  P04632
International Prot ID:  IPI00025084
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0004198  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0008284     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S34NVLGGLISGAGGGGG
Site 2T85PEPPPPRTHYSNIEA
Site 3Y87PPPPRTHYSNIEANE
Site 4S88PPPRTHYSNIEANES
Site 5S95SNIEANESEEVRQFR
Site 6S116AGDDMEVSATELMNI
Site 7T118DDMEVSATELMNILN
Site 8T129NILNKVVTRHPDLKT
Site 9T136TRHPDLKTDGFGIDT
Site 10S146FGIDTCRSMVAVMDS
Site 11T155VAVMDSDTTGKLGFE
Site 12Y166LGFEEFKYLWNNIKR
Site 13Y178IKRWQAIYKQFDTDR
Site 14T183AIYKQFDTDRSGTIC
Site 15S186KQFDTDRSGTICSSE
Site 16T188FDTDRSGTICSSELP
Site 17S191DRSGTICSSELPGAF
Site 18S192RSGTICSSELPGAFE
Site 19Y210FHLNEHLYNMIIRRY
Site 20Y217YNMIIRRYSDESGNM
Site 21S218NMIIRRYSDESGNMD
Site 22S221IRRYSDESGNMDFDN
Site 23S245AMFRAFKSLDKDGTG
Site 24T251KSLDKDGTGQIQVNI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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