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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMY1A
Full Name:
Alpha-amylase 1
Alias:
1,4-alpha-D-glucan glucanohydrolase 1
Type:
Mass (Da):
57750
Number AA:
511
UniProt ID:
P04745
International Prot ID:
IPI00300786
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004553
GO:0004556
PhosphoSite+
KinaseNET
Biological Process:
GO:0005975
GO:0007586
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
I
G
F
C
W
A
Q
Y
S
S
N
T
Q
Q
G
Site 2
S58
G
F
G
G
V
Q
V
S
P
P
N
E
N
V
A
Site 3
Y77
F
R
P
W
W
E
R
Y
Q
P
V
S
Y
K
L
Site 4
S88
S
Y
K
L
C
T
R
S
G
N
E
D
E
F
R
Site 5
S127
N
A
V
S
A
G
T
S
S
T
C
G
S
Y
F
Site 6
S128
A
V
S
A
G
T
S
S
T
C
G
S
Y
F
N
Site 7
S132
G
T
S
S
T
C
G
S
Y
F
N
P
G
S
R
Site 8
Y133
T
S
S
T
C
G
S
Y
F
N
P
G
S
R
D
Site 9
S138
G
S
Y
F
N
P
G
S
R
D
F
P
A
V
P
Site 10
S160
D
G
K
C
K
T
G
S
G
D
I
E
N
Y
N
Site 11
Y166
G
S
G
D
I
E
N
Y
N
D
A
T
Q
V
R
Site 12
T170
I
E
N
Y
N
D
A
T
Q
V
R
D
C
R
L
Site 13
Y189
D
L
A
L
G
K
D
Y
V
R
S
K
I
A
E
Site 14
S234
D
K
L
H
N
L
N
S
N
W
F
P
E
G
S
Site 15
Y246
E
G
S
K
P
F
I
Y
Q
E
V
I
D
L
G
Site 16
S259
L
G
G
E
P
I
K
S
S
D
Y
F
G
N
G
Site 17
S260
G
G
E
P
I
K
S
S
D
Y
F
G
N
G
R
Site 18
Y262
E
P
I
K
S
S
D
Y
F
G
N
G
R
V
T
Site 19
T269
Y
F
G
N
G
R
V
T
E
F
K
Y
G
A
K
Site 20
Y273
G
R
V
T
E
F
K
Y
G
A
K
L
G
T
V
Site 21
T279
K
Y
G
A
K
L
G
T
V
I
R
K
W
N
G
Site 22
Y291
W
N
G
E
K
M
S
Y
L
K
N
W
G
E
G
Site 23
T351
L
A
H
P
Y
G
F
T
R
V
M
S
S
Y
R
Site 24
Y357
F
T
R
V
M
S
S
Y
R
W
P
R
Y
F
E
Site 25
Y362
S
S
Y
R
W
P
R
Y
F
E
N
G
K
D
V
Site 26
T386
N
G
V
T
K
E
V
T
I
N
P
D
T
T
C
Site 27
Y425
G
Q
P
F
T
N
W
Y
D
N
G
S
N
Q
V
Site 28
S452
N
N
D
D
W
T
F
S
L
T
L
Q
T
G
L
Site 29
T454
D
D
W
T
F
S
L
T
L
Q
T
G
L
P
A
Site 30
Y483
N
C
T
G
I
K
I
Y
V
S
D
D
G
K
A
Site 31
S485
T
G
I
K
I
Y
V
S
D
D
G
K
A
H
F
Site 32
S493
D
D
G
K
A
H
F
S
I
S
N
S
A
E
D
Site 33
S495
G
K
A
H
F
S
I
S
N
S
A
E
D
P
F
Site 34
S497
A
H
F
S
I
S
N
S
A
E
D
P
F
I
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation