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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMY2A
Full Name:
Pancreatic alpha-amylase
Alias:
1,4-alpha-D-glucan glucanohydrolase
Type:
Mass (Da):
57707
Number AA:
511
UniProt ID:
P04746
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S58
G
F
G
G
V
Q
V
S
P
P
N
E
N
V
A
Site 2
Y67
P
N
E
N
V
A
I
Y
N
P
F
R
P
W
W
Site 3
Y77
F
R
P
W
W
E
R
Y
Q
P
V
S
Y
K
L
Site 4
S88
S
Y
K
L
C
T
R
S
G
N
E
D
E
F
R
Site 5
S127
N
A
V
S
A
G
T
S
S
T
C
G
S
Y
F
Site 6
S128
A
V
S
A
G
T
S
S
T
C
G
S
Y
F
N
Site 7
S132
G
T
S
S
T
C
G
S
Y
F
N
P
G
S
R
Site 8
Y133
T
S
S
T
C
G
S
Y
F
N
P
G
S
R
D
Site 9
S138
G
S
Y
F
N
P
G
S
R
D
F
P
A
V
P
Site 10
S160
D
G
K
C
K
T
G
S
G
D
I
E
N
Y
N
Site 11
Y166
G
S
G
D
I
E
N
Y
N
D
A
T
Q
V
R
Site 12
T170
I
E
N
Y
N
D
A
T
Q
V
R
D
C
R
L
Site 13
Y189
D
L
A
L
E
K
D
Y
V
R
S
K
I
A
E
Site 14
Y197
V
R
S
K
I
A
E
Y
M
N
H
L
I
D
I
Site 15
S259
L
G
G
E
P
I
K
S
S
D
Y
F
G
N
G
Site 16
S260
G
G
E
P
I
K
S
S
D
Y
F
G
N
G
R
Site 17
Y262
E
P
I
K
S
S
D
Y
F
G
N
G
R
V
T
Site 18
T269
Y
F
G
N
G
R
V
T
E
F
K
Y
G
A
K
Site 19
Y273
G
R
V
T
E
F
K
Y
G
A
K
L
G
T
V
Site 20
T279
K
Y
G
A
K
L
G
T
V
I
R
K
W
N
G
Site 21
Y291
W
N
G
E
K
M
S
Y
L
K
N
W
G
E
G
Site 22
T351
L
A
H
P
Y
G
F
T
R
V
M
S
S
Y
R
Site 23
Y357
F
T
R
V
M
S
S
Y
R
W
P
R
Q
F
Q
Site 24
T386
N
G
V
I
K
E
V
T
I
N
P
D
T
T
C
Site 25
Y425
G
Q
P
F
T
N
W
Y
D
N
G
S
N
Q
V
Site 26
S452
N
N
D
D
W
S
F
S
L
T
L
Q
T
G
L
Site 27
T454
D
D
W
S
F
S
L
T
L
Q
T
G
L
P
A
Site 28
Y483
N
C
T
G
I
K
I
Y
V
S
D
D
G
K
A
Site 29
S485
T
G
I
K
I
Y
V
S
D
D
G
K
A
H
F
Site 30
S493
D
D
G
K
A
H
F
S
I
S
N
S
A
E
D
Site 31
S495
G
K
A
H
F
S
I
S
N
S
A
E
D
P
F
Site 32
S497
A
H
F
S
I
S
N
S
A
E
D
P
F
I
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation