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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSPB1
Full Name:
Heat shock protein beta-1
Alias:
28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Growth-related 25 kDa protein; Heat shock 27 kDa protein; Heat shock 27kDa protein 1; Hs.76067; HSP 27; HSP25; HSP28; P25; SRP27; Stress-responsive protein 27
Type:
Chaperone protein
Mass (Da):
22783
Number AA:
205
UniProt ID:
P04792
International Prot ID:
IPI00025512
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0005634
GO:0005819
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0005515
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0008219
GO:0006928
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
T
E
R
R
V
P
F
S
L
L
R
G
P
S
W
Site 2
S15
F
S
L
L
R
G
P
S
W
D
P
F
R
D
W
Site 3
Y23
W
D
P
F
R
D
W
Y
P
H
S
R
L
F
D
Site 4
S26
F
R
D
W
Y
P
H
S
R
L
F
D
Q
A
F
Site 5
S43
P
R
L
P
E
E
W
S
Q
W
L
G
G
S
S
Site 6
Y54
G
G
S
S
W
P
G
Y
V
R
P
L
P
P
A
Site 7
S65
L
P
P
A
A
I
E
S
P
A
V
A
A
P
A
Site 8
Y73
P
A
V
A
A
P
A
Y
S
R
A
L
S
R
Q
Site 9
S74
A
V
A
A
P
A
Y
S
R
A
L
S
R
Q
L
Site 10
S78
P
A
Y
S
R
A
L
S
R
Q
L
S
S
G
V
Site 11
S82
R
A
L
S
R
Q
L
S
S
G
V
S
E
I
R
Site 12
S83
A
L
S
R
Q
L
S
S
G
V
S
E
I
R
H
Site 13
S86
R
Q
L
S
S
G
V
S
E
I
R
H
T
A
D
Site 14
T91
G
V
S
E
I
R
H
T
A
D
R
W
R
V
S
Site 15
S98
T
A
D
R
W
R
V
S
L
D
V
N
H
F
A
Site 16
T110
H
F
A
P
D
E
L
T
V
K
T
K
D
G
V
Site 17
T113
P
D
E
L
T
V
K
T
K
D
G
V
V
E
I
Site 18
T121
K
D
G
V
V
E
I
T
G
K
H
E
E
R
Q
Site 19
Y133
E
R
Q
D
E
H
G
Y
I
S
R
C
F
T
R
Site 20
S135
Q
D
E
H
G
Y
I
S
R
C
F
T
R
K
Y
Site 21
T139
G
Y
I
S
R
C
F
T
R
K
Y
T
L
P
P
Site 22
Y142
S
R
C
F
T
R
K
Y
T
L
P
P
G
V
D
Site 23
T143
R
C
F
T
R
K
Y
T
L
P
P
G
V
D
P
Site 24
T151
L
P
P
G
V
D
P
T
Q
V
S
S
S
L
S
Site 25
S154
G
V
D
P
T
Q
V
S
S
S
L
S
P
E
G
Site 26
S156
D
P
T
Q
V
S
S
S
L
S
P
E
G
T
L
Site 27
S158
T
Q
V
S
S
S
L
S
P
E
G
T
L
T
V
Site 28
T162
S
S
L
S
P
E
G
T
L
T
V
E
A
P
M
Site 29
T164
L
S
P
E
G
T
L
T
V
E
A
P
M
P
K
Site 30
T174
A
P
M
P
K
L
A
T
Q
S
N
E
I
T
I
Site 31
S176
M
P
K
L
A
T
Q
S
N
E
I
T
I
P
V
Site 32
T180
A
T
Q
S
N
E
I
T
I
P
V
T
F
E
S
Site 33
T184
N
E
I
T
I
P
V
T
F
E
S
R
A
Q
L
Site 34
S187
T
I
P
V
T
F
E
S
R
A
Q
L
G
G
P
Site 35
S199
G
G
P
E
A
A
K
S
D
E
T
A
A
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation