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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALDOB
Full Name:
Fructose-bisphosphate aldolase B
Alias:
ALDB; ALD-B; ALDO-B; Aldolase B, fructose-bisphosphate; ALFB; Liver-type aldolase
Type:
Carbohydrate Metabolism - fructose and mannose; EC 4.1.2.13; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Lyase; Carbohydrate Metabolism - pentose phosphate pathway
Mass (Da):
39473
Number AA:
364
UniProt ID:
P05062
International Prot ID:
IPI00218407
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0034451
Uniprot
OncoNet
Molecular Function:
GO:0051117
GO:0008092
GO:0070061
PhosphoSite+
KinaseNET
Biological Process:
GO:0006116
GO:0030388
GO:0006096
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
H
R
F
P
A
L
T
Q
E
Q
K
K
E
L
Site 2
S17
Q
E
Q
K
K
E
L
S
E
I
A
Q
S
I
V
Site 3
S22
E
L
S
E
I
A
Q
S
I
V
A
N
G
K
G
Site 4
S36
G
I
L
A
A
D
E
S
V
G
T
M
G
N
R
Site 5
T39
A
A
D
E
S
V
G
T
M
G
N
R
L
Q
R
Site 6
S65
Q
F
R
E
I
L
F
S
V
D
S
S
I
N
Q
Site 7
Y85
I
L
F
H
E
T
L
Y
Q
K
D
S
Q
G
K
Site 8
S89
E
T
L
Y
Q
K
D
S
Q
G
K
L
F
R
N
Site 9
T123
A
G
T
N
K
E
T
T
I
Q
G
L
D
G
L
Site 10
T124
A
G
T
N
K
E
T
T
I
Q
G
L
D
G
L
Site 11
S132
I
Q
G
L
D
G
L
S
E
R
C
A
Q
Y
K
Site 12
S161
I
A
D
Q
C
P
S
S
L
A
I
Q
E
N
A
Site 13
S176
N
A
L
A
R
Y
A
S
I
C
Q
Q
N
G
L
Site 14
Y204
H
D
L
E
H
C
Q
Y
V
T
E
K
V
L
A
Site 15
T206
L
E
H
C
Q
Y
V
T
E
K
V
L
A
A
V
Site 16
Y214
E
K
V
L
A
A
V
Y
K
A
L
N
D
H
H
Site 17
Y223
A
L
N
D
H
H
V
Y
L
E
G
T
L
L
K
Site 18
T245
H
A
C
T
K
K
Y
T
P
E
Q
V
A
M
A
Site 19
S272
V
P
G
I
C
F
L
S
G
G
M
S
E
E
D
Site 20
S276
C
F
L
S
G
G
M
S
E
E
D
A
T
L
N
Site 21
T281
G
M
S
E
E
D
A
T
L
N
L
N
A
I
N
Site 22
S299
L
P
K
P
W
K
L
S
F
S
Y
G
R
A
L
Site 23
S301
K
P
W
K
L
S
F
S
Y
G
R
A
L
Q
A
Site 24
Y302
P
W
K
L
S
F
S
Y
G
R
A
L
Q
A
S
Site 25
S309
Y
G
R
A
L
Q
A
S
A
L
A
A
W
G
G
Site 26
Y343
C
Q
A
A
K
G
Q
Y
V
H
T
G
S
S
G
Site 27
S348
G
Q
Y
V
H
T
G
S
S
G
A
A
S
T
Q
Site 28
S349
Q
Y
V
H
T
G
S
S
G
A
A
S
T
Q
S
Site 29
S353
T
G
S
S
G
A
A
S
T
Q
S
L
F
T
A
Site 30
Y362
Q
S
L
F
T
A
C
Y
T
Y
_
_
_
_
_
Site 31
T363
S
L
F
T
A
C
Y
T
Y
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation