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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARG1
Full Name:
Arginase-1
Alias:
ARGI1; Arginase, liver; Liver-type arginase; Type I arginase
Type:
EC 3.5.3.1; Amino Acid Metabolism - arginine and proline; Hydrolase
Mass (Da):
34716
Number AA:
322
UniProt ID:
P05089
International Prot ID:
IPI00291560
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0004053
GO:0030145
PhosphoSite+
KinaseNET
Biological Process:
GO:0006527
GO:0000050
Phosida
TranscriptoNet
STRING
Kinexus Products
Arginase-1 (314-322, human) peptide, C1 for conjugation - Powder PE-01APG95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01APG95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
S
A
K
S
R
T
I
G
I
I
G
A
P
Site 2
S16
G
I
I
G
A
P
F
S
K
G
Q
P
R
G
G
Site 3
T29
G
G
V
E
E
G
P
T
V
L
R
K
A
G
L
Site 4
Y50
Q
E
C
D
V
K
D
Y
G
D
L
P
F
A
D
Site 5
S62
F
A
D
I
P
N
D
S
P
F
Q
I
V
K
N
Site 6
S72
Q
I
V
K
N
P
R
S
V
G
K
A
S
E
Q
Site 7
S94
V
K
K
N
G
R
I
S
L
V
L
G
G
D
H
Site 8
S102
L
V
L
G
G
D
H
S
L
A
I
G
S
I
S
Site 9
S107
D
H
S
L
A
I
G
S
I
S
G
H
A
R
V
Site 10
S109
S
L
A
I
G
S
I
S
G
H
A
R
V
H
P
Site 11
T131
D
A
H
T
D
I
N
T
P
L
T
T
T
S
G
Site 12
T134
T
D
I
N
T
P
L
T
T
T
S
G
N
L
H
Site 13
T135
D
I
N
T
P
L
T
T
T
S
G
N
L
H
G
Site 14
S146
N
L
H
G
Q
P
V
S
F
L
L
K
E
L
K
Site 15
S163
I
P
D
V
P
G
F
S
W
V
T
P
C
I
S
Site 16
T166
V
P
G
F
S
W
V
T
P
C
I
S
A
K
D
Site 17
Y188
D
V
D
P
G
E
H
Y
I
L
K
T
L
G
I
Site 18
T192
G
E
H
Y
I
L
K
T
L
G
I
K
Y
F
S
Site 19
S217
K
V
M
E
E
T
L
S
Y
L
L
G
R
K
K
Site 20
Y218
V
M
E
E
T
L
S
Y
L
L
G
R
K
K
R
Site 21
S230
K
K
R
P
I
H
L
S
F
D
V
D
G
L
D
Site 22
S239
D
V
D
G
L
D
P
S
F
T
P
A
T
G
T
Site 23
T241
D
G
L
D
P
S
F
T
P
A
T
G
T
P
V
Site 24
T244
D
P
S
F
T
P
A
T
G
T
P
V
V
G
G
Site 25
T246
S
F
T
P
A
T
G
T
P
V
V
G
G
L
T
Site 26
Y259
L
T
Y
R
E
G
L
Y
I
T
E
E
I
Y
K
Site 27
Y265
L
Y
I
T
E
E
I
Y
K
T
G
L
L
S
G
Site 28
S281
D
I
M
E
V
N
P
S
L
G
K
T
P
E
E
Site 29
T285
V
N
P
S
L
G
K
T
P
E
E
V
T
R
T
Site 30
Y317
G
N
H
K
P
I
D
Y
L
N
P
P
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation