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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP11A1
Full Name:
Cholesterol side-chain cleavage enzyme, mitochondrial
Alias:
CYPXIA1;Cholesterol desmolase;Cytochrome P450 11A1;Cytochrome P450(scc)
Type:
Mass (Da):
60102
Number AA:
521
UniProt ID:
P05108
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
K
G
L
P
P
R
S
V
L
V
K
G
C
Q
Site 2
S21
K
G
C
Q
T
F
L
S
A
P
R
E
G
L
G
Site 3
T34
L
G
R
L
R
V
P
T
G
E
G
A
G
I
S
Site 4
S41
T
G
E
G
A
G
I
S
T
R
S
P
R
P
F
Site 5
T42
G
E
G
A
G
I
S
T
R
S
P
R
P
F
N
Site 6
S44
G
A
G
I
S
T
R
S
P
R
P
F
N
E
I
Site 7
S53
R
P
F
N
E
I
P
S
P
G
D
N
G
W
L
Site 8
Y85
H
V
Q
N
F
Q
K
Y
G
P
I
Y
R
E
K
Site 9
Y89
F
Q
K
Y
G
P
I
Y
R
E
K
L
G
N
V
Site 10
S98
E
K
L
G
N
V
E
S
V
Y
V
I
D
P
E
Site 11
S113
D
V
A
L
L
F
K
S
E
G
P
N
P
E
R
Site 12
Y133
W
V
A
Y
H
Q
Y
Y
Q
R
P
I
G
V
L
Site 13
S144
I
G
V
L
L
K
K
S
A
A
W
K
K
D
R
Site 14
S180
A
V
S
R
D
F
V
S
V
L
H
R
R
I
K
Site 15
S191
R
R
I
K
K
A
G
S
G
N
Y
S
G
D
I
Site 16
S195
K
A
G
S
G
N
Y
S
G
D
I
S
D
D
L
Site 17
S199
G
N
Y
S
G
D
I
S
D
D
L
F
R
F
A
Site 18
T262
F
R
L
F
R
T
K
T
W
K
D
H
V
A
A
Site 19
Y280
I
F
S
K
A
D
I
Y
T
Q
N
F
Y
W
E
Site 20
Y285
D
I
Y
T
Q
N
F
Y
W
E
L
R
Q
K
G
Site 21
Y298
K
G
S
V
H
H
D
Y
R
G
I
L
Y
R
L
Site 22
Y303
H
D
Y
R
G
I
L
Y
R
L
L
G
D
S
K
Site 23
S309
L
Y
R
L
L
G
D
S
K
M
S
F
E
D
I
Site 24
S312
L
L
G
D
S
K
M
S
F
E
D
I
K
A
N
Site 25
Y340
M
T
L
Q
W
H
L
Y
E
M
A
R
N
L
K
Site 26
T384
L
K
A
S
I
K
E
T
L
R
L
H
P
I
S
Site 27
T393
R
L
H
P
I
S
V
T
L
Q
R
Y
L
V
N
Site 28
T427
Y
A
L
G
R
E
P
T
F
F
F
D
P
E
N
Site 29
T438
D
P
E
N
F
D
P
T
R
W
L
S
K
D
K
Site 30
T448
L
S
K
D
K
N
I
T
Y
F
R
N
L
G
F
Site 31
Y449
S
K
D
K
N
I
T
Y
F
R
N
L
G
F
G
Site 32
S491
R
V
E
I
Q
H
L
S
D
V
G
T
T
F
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation