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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPING1
Full Name:
Plasma protease C1 inhibitor
Alias:
C1 esterase inhibitor;C1-inhibiting factor;Serpin G1
Type:
Mass (Da):
55154
Number AA:
500
UniProt ID:
P05155
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
L
L
A
G
D
R
A
S
S
N
P
N
A
T
S
Site 2
S22
L
A
G
D
R
A
S
S
N
P
N
A
T
S
S
Site 3
T27
A
S
S
N
P
N
A
T
S
S
S
S
Q
D
P
Site 4
S28
S
S
N
P
N
A
T
S
S
S
S
Q
D
P
E
Site 5
S29
S
N
P
N
A
T
S
S
S
S
Q
D
P
E
S
Site 6
S31
P
N
A
T
S
S
S
S
Q
D
P
E
S
L
Q
Site 7
S36
S
S
S
Q
D
P
E
S
L
Q
D
R
G
E
G
Site 8
S64
E
P
I
L
E
V
S
S
L
P
T
T
N
S
T
Site 9
T67
L
E
V
S
S
L
P
T
T
N
S
T
T
N
S
Site 10
T68
E
V
S
S
L
P
T
T
N
S
T
T
N
S
A
Site 11
S70
S
S
L
P
T
T
N
S
T
T
N
S
A
T
K
Site 12
S74
T
T
N
S
T
T
N
S
A
T
K
I
T
A
N
Site 13
T83
T
K
I
T
A
N
T
T
D
E
P
T
T
Q
P
Site 14
T87
A
N
T
T
D
E
P
T
T
Q
P
T
T
E
P
Site 15
T107
I
Q
P
T
Q
P
T
T
Q
L
P
T
D
S
P
Site 16
T111
Q
P
T
T
Q
L
P
T
D
S
P
T
Q
P
T
Site 17
S113
T
T
Q
L
P
T
D
S
P
T
Q
P
T
T
G
Site 18
T115
Q
L
P
T
D
S
P
T
Q
P
T
T
G
S
F
Site 19
T119
D
S
P
T
Q
P
T
T
G
S
F
C
P
G
P
Site 20
S121
P
T
Q
P
T
T
G
S
F
C
P
G
P
V
T
Site 21
S131
P
G
P
V
T
L
C
S
D
L
E
S
H
S
T
Site 22
S135
T
L
C
S
D
L
E
S
H
S
T
E
A
V
L
Site 23
S137
C
S
D
L
E
S
H
S
T
E
A
V
L
G
D
Site 24
T138
S
D
L
E
S
H
S
T
E
A
V
L
G
D
A
Site 25
S158
L
K
L
Y
H
A
F
S
A
M
K
K
V
E
T
Site 26
T191
G
A
G
E
N
T
K
T
N
L
E
S
I
L
S
Site 27
S198
T
N
L
E
S
I
L
S
Y
P
K
D
F
T
C
Site 28
Y199
N
L
E
S
I
L
S
Y
P
K
D
F
T
C
V
Site 29
T204
L
S
Y
P
K
D
F
T
C
V
H
Q
A
L
K
Site 30
T215
Q
A
L
K
G
F
T
T
K
G
V
T
S
V
S
Site 31
S222
T
K
G
V
T
S
V
S
Q
I
F
H
S
P
D
Site 32
S227
S
V
S
Q
I
F
H
S
P
D
L
A
I
R
D
Site 33
T235
P
D
L
A
I
R
D
T
F
V
N
A
S
R
T
Site 34
S240
R
D
T
F
V
N
A
S
R
T
L
Y
S
S
S
Site 35
T242
T
F
V
N
A
S
R
T
L
Y
S
S
S
P
R
Site 36
Y244
V
N
A
S
R
T
L
Y
S
S
S
P
R
V
L
Site 37
S245
N
A
S
R
T
L
Y
S
S
S
P
R
V
L
S
Site 38
S246
A
S
R
T
L
Y
S
S
S
P
R
V
L
S
N
Site 39
S247
S
R
T
L
Y
S
S
S
P
R
V
L
S
N
N
Site 40
S252
S
S
S
P
R
V
L
S
N
N
S
D
A
N
L
Site 41
S255
P
R
V
L
S
N
N
S
D
A
N
L
E
L
I
Site 42
T264
A
N
L
E
L
I
N
T
W
V
A
K
N
T
N
Site 43
S280
K
I
S
R
L
L
D
S
L
P
S
D
T
R
L
Site 44
Y294
L
V
L
L
N
A
I
Y
L
S
A
K
W
K
T
Site 45
S296
L
L
N
A
I
Y
L
S
A
K
W
K
T
T
F
Site 46
T302
L
S
A
K
W
K
T
T
F
D
P
K
K
T
R
Site 47
Y330
P
M
M
N
S
K
K
Y
P
V
A
H
F
I
D
Site 48
T339
V
A
H
F
I
D
Q
T
L
K
A
K
V
G
Q
Site 49
S375
E
D
M
E
Q
A
L
S
P
S
V
F
K
A
I
Site 50
S406
P
R
I
K
V
T
T
S
Q
D
M
L
S
I
M
Site 51
S411
T
T
S
Q
D
M
L
S
I
M
E
K
L
E
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation