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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
F13B
Full Name:
Coagulation factor XIII B chain
Alias:
Fibrin-stabilizing factor B subunit;Protein-glutamine gamma-glutamyltransferase B chain;Transglutaminase B chain
Type:
Mass (Da):
75511
Number AA:
661
UniProt ID:
P05160
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
E
N
G
R
I
A
Q
Y
Y
Y
T
F
K
S
F
Site 2
Y39
N
G
R
I
A
Q
Y
Y
Y
T
F
K
S
F
Y
Site 3
Y40
G
R
I
A
Q
Y
Y
Y
T
F
K
S
F
Y
F
Site 4
Y46
Y
Y
T
F
K
S
F
Y
F
P
M
S
I
D
K
Site 5
S50
K
S
F
Y
F
P
M
S
I
D
K
K
L
S
F
Site 6
Y63
S
F
F
C
L
A
G
Y
T
T
E
S
G
R
Q
Site 7
S67
L
A
G
Y
T
T
E
S
G
R
Q
E
E
Q
T
Site 8
T74
S
G
R
Q
E
E
Q
T
T
C
T
T
E
G
W
Site 9
T75
G
R
Q
E
E
Q
T
T
C
T
T
E
G
W
S
Site 10
S97
K
C
T
K
P
D
L
S
N
G
Y
I
S
D
V
Site 11
Y108
I
S
D
V
K
L
L
Y
K
I
Q
E
N
M
R
Site 12
Y116
K
I
Q
E
N
M
R
Y
G
C
A
S
G
Y
K
Site 13
Y122
R
Y
G
C
A
S
G
Y
K
T
T
G
G
K
D
Site 14
T124
G
C
A
S
G
Y
K
T
T
G
G
K
D
E
E
Site 15
S137
E
E
V
V
Q
C
L
S
D
G
W
S
S
Q
P
Site 16
S141
Q
C
L
S
D
G
W
S
S
Q
P
T
C
R
K
Site 17
T145
D
G
W
S
S
Q
P
T
C
R
K
E
H
E
T
Site 18
T152
T
C
R
K
E
H
E
T
C
L
A
P
E
L
Y
Site 19
Y159
T
C
L
A
P
E
L
Y
N
G
N
Y
S
T
T
Site 20
S164
E
L
Y
N
G
N
Y
S
T
T
Q
K
T
F
K
Site 21
T169
N
Y
S
T
T
Q
K
T
F
K
V
K
D
K
V
Site 22
Y178
K
V
K
D
K
V
Q
Y
E
C
A
T
G
Y
Y
Site 23
Y184
Q
Y
E
C
A
T
G
Y
Y
T
A
G
G
K
K
Site 24
T199
T
E
E
V
E
C
L
T
Y
G
W
S
L
T
P
Site 25
Y200
E
E
V
E
C
L
T
Y
G
W
S
L
T
P
K
Site 26
T205
L
T
Y
G
W
S
L
T
P
K
C
T
K
L
K
Site 27
T209
W
S
L
T
P
K
C
T
K
L
K
C
S
S
L
Site 28
S215
C
T
K
L
K
C
S
S
L
R
L
I
E
N
G
Site 29
Y223
L
R
L
I
E
N
G
Y
F
H
P
V
K
Q
T
Site 30
Y245
Q
F
F
C
H
E
N
Y
Y
L
S
G
S
D
L
Site 31
Y246
F
F
C
H
E
N
Y
Y
L
S
G
S
D
L
I
Site 32
Y256
G
S
D
L
I
Q
C
Y
N
F
G
W
Y
P
E
Site 33
S264
N
F
G
W
Y
P
E
S
P
V
C
E
G
R
R
Site 34
S283
P
P
P
L
P
I
N
S
K
I
Q
T
H
S
T
Site 35
T287
P
I
N
S
K
I
Q
T
H
S
T
T
Y
R
H
Site 36
S289
N
S
K
I
Q
T
H
S
T
T
Y
R
H
G
E
Site 37
T290
S
K
I
Q
T
H
S
T
T
Y
R
H
G
E
I
Site 38
T291
K
I
Q
T
H
S
T
T
Y
R
H
G
E
I
V
Site 39
S311
L
N
F
E
I
H
G
S
A
E
I
R
C
E
D
Site 40
Y355
N
L
H
S
K
I
Y
Y
N
G
D
K
V
T
Y
Site 41
Y362
Y
N
G
D
K
V
T
Y
A
C
K
S
G
Y
L
Site 42
S366
K
V
T
Y
A
C
K
S
G
Y
L
L
H
G
S
Site 43
Y368
T
Y
A
C
K
S
G
Y
L
L
H
G
S
N
E
Site 44
S373
S
G
Y
L
L
H
G
S
N
E
I
T
C
N
R
Site 45
T384
T
C
N
R
G
K
W
T
L
P
P
E
C
V
E
Site 46
Y423
A
T
G
S
S
V
E
Y
R
C
N
E
Y
Y
L
Site 47
Y428
V
E
Y
R
C
N
E
Y
Y
L
L
R
G
S
K
Site 48
Y429
E
Y
R
C
N
E
Y
Y
L
L
R
G
S
K
I
Site 49
S434
E
Y
Y
L
L
R
G
S
K
I
S
R
C
E
Q
Site 50
S437
L
L
R
G
S
K
I
S
R
C
E
Q
G
K
W
Site 51
S446
C
E
Q
G
K
W
S
S
P
P
V
C
L
E
P
Site 52
Y460
P
C
T
V
N
V
D
Y
M
N
R
N
N
I
E
Site 53
Y472
N
I
E
M
K
W
K
Y
E
G
K
V
L
H
G
Site 54
S493
C
K
Q
G
Y
D
L
S
P
L
T
P
L
S
E
Site 55
Y512
C
N
R
G
E
V
K
Y
P
L
C
T
R
K
E
Site 56
S520
P
L
C
T
R
K
E
S
K
G
M
C
T
S
P
Site 57
S526
E
S
K
G
M
C
T
S
P
P
L
I
K
H
G
Site 58
S538
K
H
G
V
I
I
S
S
T
V
D
T
Y
E
N
Site 59
T539
H
G
V
I
I
S
S
T
V
D
T
Y
E
N
G
Site 60
T542
I
I
S
S
T
V
D
T
Y
E
N
G
S
S
V
Site 61
Y543
I
S
S
T
V
D
T
Y
E
N
G
S
S
V
E
Site 62
Y551
E
N
G
S
S
V
E
Y
R
C
F
D
H
H
F
Site 63
Y566
L
E
G
S
R
E
A
Y
C
L
D
G
M
W
T
Site 64
S585
C
L
E
P
C
T
L
S
F
T
E
M
E
K
N
Site 65
T620
E
F
I
C
R
G
D
T
Y
P
A
E
L
Y
I
Site 66
Y626
D
T
Y
P
A
E
L
Y
I
T
G
S
I
L
R
Site 67
Y643
C
D
R
G
Q
L
K
Y
P
R
C
I
P
R
Q
Site 68
S651
P
R
C
I
P
R
Q
S
T
L
S
Y
Q
E
P
Site 69
T652
R
C
I
P
R
Q
S
T
L
S
Y
Q
E
P
L
Site 70
S654
I
P
R
Q
S
T
L
S
Y
Q
E
P
L
R
T
Site 71
Y655
P
R
Q
S
T
L
S
Y
Q
E
P
L
R
T
_
Site 72
T661
S
Y
Q
E
P
L
R
T
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation