PhosphoNET

           
Protein Info 
   
Short Name:  MPO
Full Name:  Myeloperoxidase
Alias:  84 kDa myeloperoxidase; 89 kDa myeloperoxidase; EC 1.11.1.7; Myeloperoxidase heavy chain; Myeloperoxidase light chain; PERM
Type:  EC 1.11.1.7; Oxidoreductase
Mass (Da):  83869
Number AA:  745
UniProt ID:  P05164
International Prot ID:  IPI00236556
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005615  GO:0005764  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0003682  GO:0020037 PhosphoSite+ KinaseNET
Biological Process:  GO:0006916  GO:0006952  GO:0042744 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S64VDTSLVLSSMEEAKQ
Site 2Y77KQLVDKAYKERRESI
Site 3S83AYKERRESIKQRLRS
Site 4S90SIKQRLRSGSASPME
Site 5S92KQRLRSGSASPMELL
Site 6S94RLRSGSASPMELLSY
Site 7S132LLERKLRSLWRRPFN
Site 8T141WRRPFNVTDVLTPAQ
Site 9S153PAQLNVLSKSSGCAY
Site 10S155QLNVLSKSSGCAYQD
Site 11Y160SKSSGCAYQDVGVTC
Site 12Y173TCPEQDKYRTITGMC
Site 13T177QDKYRTITGMCNNRR
Site 14S185GMCNNRRSPTLGASN
Site 15T187CNNRRSPTLGASNRA
Site 16S191RSPTLGASNRAFVRW
Site 17Y203VRWLPAEYEDGFSLP
Site 18S208AEYEDGFSLPYGWTP
Site 19Y211EDGFSLPYGWTPGVK
Site 20T214FSLPYGWTPGVKRNG
Site 21T239NEIVRFPTDQLTPDQ
Site 22T243RFPTDQLTPDQERSL
Site 23T266LDHDLDFTPEPAARA
Site 24S357ARNLRNMSNQLGLLA
Site 25T390HDDPCLLTNRSARIP
Site 26T404PCFLAGDTRSSEMPE
Site 27S407LAGDTRSSEMPELTS
Site 28T428REHNRLATELKSLNP
Site 29S432RLATELKSLNPRWDG
Site 30Y443RWDGERLYQEARKIV
Site 31Y475GPTAMRKYLPTYRSY
Site 32T478AMRKYLPTYRSYNDS
Site 33Y479MRKYLPTYRSYNDSV
Site 34S481KYLPTYRSYNDSVDP
Site 35Y482YLPTYRSYNDSVDPR
Site 36S485TYRSYNDSVDPRIAN
Site 37Y500VFTNAFRYGHTLIQP
Site 38Y516MFRLDNRYQPMEPNP
Site 39S528PNPRVPLSRVFFASW
Site 40T553ILRGLMATPAKLNRQ
Site 41S591PALNMQRSRDHGLPG
Site 42Y599RDHGLPGYNAWRRFC
Site 43Y634ARKLMEQYGTPNNID
Site 44T707PRIICDNTGITTVSK
Site 45T711CDNTGITTVSKNNIF
Site 46S720SKNNIFMSNSYPRDF
Site 47Y723NIFMSNSYPRDFVNC
Site 48S740LPALNLASWREAS__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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