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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
JUN
Full Name:
Transcription factor AP-1
Alias:
Activator protein 1; AH119; AP1; AP-1; C-Jun; Jun A; Jun oncogene; P39; Proto-oncogene c-jun; RJG-9; V-jun avian sarcoma virus 17 oncogene homolog
Type:
Transcription protein
Mass (Da):
35676
Number AA:
331
UniProt ID:
P05412
International Prot ID:
IPI00008965
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0070412
GO:0003702
GO:0005100
PhosphoSite+
KinaseNET
Biological Process:
GO:0007184
GO:0060395
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Jun transcription factor (AP1) S63 phosphosite-specific antibody AB-PN557#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN557#Jun transcription factor (AP1) (D59-G67, human) pS63 phosphopeptide - Powder PE-04ARC85#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04ARC85
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
A
K
M
E
T
T
F
Site 2
T8
M
T
A
K
M
E
T
T
F
Y
D
D
A
L
N
Site 3
Y10
A
K
M
E
T
T
F
Y
D
D
A
L
N
A
S
Site 4
S17
Y
D
D
A
L
N
A
S
F
L
P
S
E
S
G
Site 5
S21
L
N
A
S
F
L
P
S
E
S
G
P
Y
G
Y
Site 6
S23
A
S
F
L
P
S
E
S
G
P
Y
G
Y
S
N
Site 7
Y26
L
P
S
E
S
G
P
Y
G
Y
S
N
P
K
I
Site 8
Y28
S
E
S
G
P
Y
G
Y
S
N
P
K
I
L
K
Site 9
S29
E
S
G
P
Y
G
Y
S
N
P
K
I
L
K
Q
Site 10
S37
N
P
K
I
L
K
Q
S
M
T
L
N
L
A
D
Site 11
S48
N
L
A
D
P
V
G
S
L
K
P
H
L
R
A
Site 12
S58
P
H
L
R
A
K
N
S
D
L
L
T
S
P
D
Site 13
T62
A
K
N
S
D
L
L
T
S
P
D
V
G
L
L
Site 14
S63
K
N
S
D
L
L
T
S
P
D
V
G
L
L
K
Jun transcription factor (AP1) S63 phosphosite-specific antibody AB-PN557#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN557#Jun transcription factor (AP1) (D59-G67, human) pS63 phosphopeptide - Powder PE-04ARC85#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04ARC85
Site 15
S73
V
G
L
L
K
L
A
S
P
E
L
E
R
L
I
Site 16
S83
L
E
R
L
I
I
Q
S
S
N
G
H
I
T
T
Site 17
S84
E
R
L
I
I
Q
S
S
N
G
H
I
T
T
T
Site 18
T89
Q
S
S
N
G
H
I
T
T
T
P
T
P
T
Q
Site 19
T91
S
N
G
H
I
T
T
T
P
T
P
T
Q
F
L
Site 20
T93
G
H
I
T
T
T
P
T
P
T
Q
F
L
C
P
Site 21
T95
I
T
T
T
P
T
P
T
Q
F
L
C
P
K
N
Site 22
S123
R
A
L
A
E
L
H
S
Q
N
T
L
P
S
V
Site 23
T126
A
E
L
H
S
Q
N
T
L
P
S
V
T
S
A
Site 24
S129
H
S
Q
N
T
L
P
S
V
T
S
A
A
Q
P
Site 25
S160
G
S
G
S
G
G
F
S
A
S
L
H
S
E
P
Site 26
S162
G
S
G
G
F
S
A
S
L
H
S
E
P
P
V
Site 27
S165
G
F
S
A
S
L
H
S
E
P
P
V
Y
A
N
Site 28
Y170
L
H
S
E
P
P
V
Y
A
N
L
S
N
F
N
Site 29
S174
P
P
V
Y
A
N
L
S
N
F
N
P
G
A
L
Site 30
S182
N
F
N
P
G
A
L
S
S
G
G
G
A
P
S
Site 31
S183
F
N
P
G
A
L
S
S
G
G
G
A
P
S
Y
Site 32
T231
A
L
K
E
E
P
Q
T
V
P
E
M
P
G
E
Site 33
T239
V
P
E
M
P
G
E
T
P
P
L
S
P
I
D
Site 34
S243
P
G
E
T
P
P
L
S
P
I
D
M
E
S
Q
Site 35
S249
L
S
P
I
D
M
E
S
Q
E
R
I
K
A
E
Site 36
S267
M
R
N
R
I
A
A
S
K
C
R
K
R
K
L
Site 37
T286
R
L
E
E
K
V
K
T
L
K
A
Q
N
S
E
Site 38
S292
K
T
L
K
A
Q
N
S
E
L
A
S
T
A
N
Site 39
S296
A
Q
N
S
E
L
A
S
T
A
N
M
L
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation