PhosphoNET

           
Protein Info 
   
Short Name:  AP-2 alpha
Full Name:  Transcription factor AP-2-alpha
Alias:  Activating enhancer binding protein 2 alpha; Activating enhancer-binding protein 2 alpha; Activator protein 2; AP-2; AP-2 transcription factor; AP2A; AP2TF; TFAP2; TFAP2A
Type:  Transcription protein
Mass (Da):  48062
Number AA:  437
UniProt ID:  P05549
International Prot ID:  IPI00743383
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0046983  GO:0003713  GO:0003700 PhosphoSite+ KinaseNET
Biological Process:  GO:0007398  GO:0006357  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y11KLTDNIKYEDCEDRH
Site 2S22EDRHDGTSNGTARLP
Site 3T33ARLPQLGTVGQSPYT
Site 4S37QLGTVGQSPYTSAPP
Site 5T40TVGQSPYTSAPPLSH
Site 6S41VGQSPYTSAPPLSHT
Site 7S46YTSAPPLSHTPNADF
Site 8T48SAPPLSHTPNADFQP
Site 9Y57NADFQPPYFPPPYQP
Site 10Y62PPYFPPPYQPIYPQS
Site 11Y66PPPYQPIYPQSQDPY
Site 12Y73YPQSQDPYSHVNDPY
Site 13S74PQSQDPYSHVNDPYS
Site 14Y80YSHVNDPYSLNPLHA
Site 15S81SHVNDPYSLNPLHAQ
Site 16S102GWPGQRQSQESGLLH
Site 17S105GQRQSQESGLLHTHR
Site 18T110QESGLLHTHRGLPHQ
Site 19S119RGLPHQLSGLDPRRD
Site 20Y127GLDPRRDYRRHEDLL
Site 21S141LHGPHALSSGLGDLS
Site 22S142HGPHALSSGLGDLSI
Site 23S148SSGLGDLSIHSLPHA
Site 24S151LGDLSIHSLPHAIEE
Site 25T173GINIPDQTVIKKGPV
Site 26S181VIKKGPVSLSKSNSN
Site 27S183KKGPVSLSKSNSNAV
Site 28S185GPVSLSKSNSNAVSA
Site 29S187VSLSKSNSNAVSAIP
Site 30S191KSNSNAVSAIPINKD
Site 31S213NPNEVFCSVPGRLSL
Site 32S219CSVPGRLSLLSSTSK
Site 33S222PGRLSLLSSTSKYKV
Site 34S223GRLSLLSSTSKYKVT
Site 35S225LSLLSSTSKYKVTVA
Site 36T230STSKYKVTVAEVQRR
Site 37S239AEVQRRLSPPECLNA
Site 38S258GVLRRAKSKNGGRSL
Site 39S264KSKNGGRSLREKLDK
Site 40T287RRKAANVTLLTSLVE
Site 41Y306HLARDFGYVCETEFP
Site 42S326EFLNRQHSDPNEQVT
Site 43S357DLLAQDRSPLGNSRP
Site 44T403TALQNYLTEALKAMD
Site 45Y413LKAMDKMYLSNNPNS
Site 46S420YLSNNPNSHTDNNAK
Site 47S428HTDNNAKSSDKEEKH
Site 48S429TDNNAKSSDKEEKHR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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