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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRYBA1
Full Name:
Beta-crystallin A3
Alias:
Beta crystallin A1; Beta-A1-crystallin; CRBA1; CRYB1; crystallin, betaA1
Type:
Chaperone protein
Mass (Da):
25150
Number AA:
215
UniProt ID:
P05813
International Prot ID:
IPI00010847
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0005212
PhosphoSite+
KinaseNET
Biological Process:
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
Q
E
L
E
T
L
P
T
T
K
M
A
Q
T
N
Site 2
T24
K
M
A
Q
T
N
P
T
P
G
S
L
G
P
W
Site 3
S27
Q
T
N
P
T
P
G
S
L
G
P
W
K
I
T
Site 4
Y36
G
P
W
K
I
T
I
Y
D
Q
E
N
F
Q
G
Site 5
S50
G
K
R
M
E
F
T
S
S
C
P
N
V
S
E
Site 6
S51
K
R
M
E
F
T
S
S
C
P
N
V
S
E
R
Site 7
S56
T
S
S
C
P
N
V
S
E
R
S
F
D
N
V
Site 8
S59
C
P
N
V
S
E
R
S
F
D
N
V
R
S
L
Site 9
S65
R
S
F
D
N
V
R
S
L
K
V
E
S
G
A
Site 10
Y76
E
S
G
A
W
I
G
Y
E
H
T
S
F
C
G
Site 11
Y93
F
I
L
E
R
G
E
Y
P
R
W
D
A
W
S
Site 12
S112
Y
H
I
E
R
L
M
S
F
R
P
I
C
S
A
Site 13
S118
M
S
F
R
P
I
C
S
A
N
H
K
E
S
K
Site 14
T127
N
H
K
E
S
K
M
T
I
F
E
K
E
N
F
Site 15
S142
I
G
R
Q
W
E
I
S
D
D
Y
P
S
L
Q
Site 16
Y145
Q
W
E
I
S
D
D
Y
P
S
L
Q
A
M
G
Site 17
S160
W
F
N
N
E
V
G
S
M
K
I
Q
S
G
A
Site 18
Y171
Q
S
G
A
W
V
C
Y
Q
Y
P
G
Y
R
G
Site 19
Y176
V
C
Y
Q
Y
P
G
Y
R
G
Y
Q
Y
I
L
Site 20
Y179
Q
Y
P
G
Y
R
G
Y
Q
Y
I
L
E
C
D
Site 21
Y181
P
G
Y
R
G
Y
Q
Y
I
L
E
C
D
H
H
Site 22
T204
E
W
G
S
H
A
Q
T
S
Q
I
Q
S
I
R
Site 23
S205
W
G
S
H
A
Q
T
S
Q
I
Q
S
I
R
R
Site 24
S209
A
Q
T
S
Q
I
Q
S
I
R
R
I
Q
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation