PhosphoNET

           
Protein Info 
   
Short Name:  CSN2
Full Name:  Beta-casein
Alias:  Beta-casein; CASB; Casein beta
Type:  Inhibitor protein; Calcium-binding protein
Mass (Da):  25382
Number AA:  226
UniProt ID:  P05814
International Prot ID:  IPI00010849
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005576     Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0004857  GO:0005215 PhosphoSite+ KinaseNET
Biological Process:  GO:0006816     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T18ALALARETIESLSSS
Site 2S21LARETIESLSSSEES
Site 3S23RETIESLSSSEESIT
Site 4S24ETIESLSSSEESITE
Site 5S25TIESLSSSEESITEY
Site 6S28SLSSSEESITEYKQK
Site 7T30SSSEESITEYKQKVE
Site 8Y32SEESITEYKQKVEKV
Site 9Y56DEHQDKIYPSFQPQP
Site 10S58HQDKIYPSFQPQPLI
Site 11T107EVPKAKDTVYTKGRV
Site 12Y109PKAKDTVYTKGRVMP
Site 13T160VPQPIPQTLALPPQP
Site 14S170LPPQPLWSVPQPKVL
Site 15Y186IPQQVVPYPQRAVPV
Site 16Y211LNPTHQIYPVTQPLA
Site 17T214THQIYPVTQPLAPVH
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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