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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PYGL
Full Name:
Glycogen phosphorylase, liver form
Alias:
EC 2.4.1.1; PHS1
Type:
Enzyme, transferase
Mass (Da):
97149
Number AA:
846
UniProt ID:
P06737
International Prot ID:
IPI00470525
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0016208
GO:0005524
GO:0032052
PhosphoSite+
KinaseNET
Biological Process:
GO:0042593
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
A
K
P
L
T
D
Q
E
K
R
R
Q
Site 2
S15
Q
E
K
R
R
Q
I
S
I
R
G
I
V
G
V
Site 3
S31
N
V
A
E
L
K
K
S
F
N
R
H
L
H
F
Site 4
T39
F
N
R
H
L
H
F
T
L
V
K
D
R
N
V
Site 5
T49
K
D
R
N
V
A
T
T
R
D
Y
Y
F
A
L
Site 6
Y52
N
V
A
T
T
R
D
Y
Y
F
A
L
A
H
T
Site 7
Y75
W
I
R
T
Q
Q
H
Y
Y
D
K
C
P
K
R
Site 8
Y76
I
R
T
Q
Q
H
Y
Y
D
K
C
P
K
R
V
Site 9
Y84
D
K
C
P
K
R
V
Y
Y
L
S
L
E
F
Y
Site 10
Y85
K
C
P
K
R
V
Y
Y
L
S
L
E
F
Y
M
Site 11
S87
P
K
R
V
Y
Y
L
S
L
E
F
Y
M
G
R
Site 12
Y91
Y
Y
L
S
L
E
F
Y
M
G
R
T
L
Q
N
Site 13
T99
M
G
R
T
L
Q
N
T
M
I
N
L
G
L
Q
Site 14
Y156
A
T
L
G
L
A
A
Y
G
Y
G
I
R
Y
E
Site 15
Y162
A
Y
G
Y
G
I
R
Y
E
Y
G
I
F
N
Q
Site 16
Y164
G
Y
G
I
R
Y
E
Y
G
I
F
N
Q
K
I
Site 17
Y186
E
A
D
D
W
L
R
Y
G
N
P
W
E
K
S
Site 18
Y204
F
M
L
P
V
H
F
Y
G
K
V
E
H
T
N
Site 19
T212
G
K
V
E
H
T
N
T
G
T
K
W
I
D
T
Site 20
Y234
Y
D
T
P
V
P
G
Y
M
N
N
T
V
N
T
Site 21
Y263
R
D
F
N
V
G
D
Y
I
Q
A
V
L
D
R
Site 22
S277
R
N
L
A
E
N
I
S
R
V
L
Y
P
N
D
Site 23
Y281
E
N
I
S
R
V
L
Y
P
N
D
N
F
F
E
Site 24
S315
I
I
R
R
F
K
A
S
K
F
G
S
T
R
G
Site 25
S319
F
K
A
S
K
F
G
S
T
R
G
A
G
T
V
Site 26
T325
G
S
T
R
G
A
G
T
V
F
D
A
F
P
D
Site 27
T379
T
F
A
Y
T
N
H
T
V
L
P
E
A
L
E
Site 28
Y405
P
R
H
L
E
I
I
Y
E
I
N
Q
K
H
L
Site 29
S430
V
D
R
L
R
R
M
S
L
I
E
E
E
G
S
Site 30
S437
S
L
I
E
E
E
G
S
K
R
I
N
M
A
H
Site 31
S473
T
K
V
F
K
D
F
S
E
L
E
P
D
K
F
Site 32
T484
P
D
K
F
Q
N
K
T
N
G
I
T
P
R
R
Site 33
T488
Q
N
K
T
N
G
I
T
P
R
R
W
L
L
L
Site 34
Y512
A
E
K
I
G
E
D
Y
V
K
D
L
S
Q
L
Site 35
S517
E
D
Y
V
K
D
L
S
Q
L
T
K
L
H
S
Site 36
T520
V
K
D
L
S
Q
L
T
K
L
H
S
F
L
G
Site 37
S524
S
Q
L
T
K
L
H
S
F
L
G
D
D
V
F
Site 38
S547
Q
E
N
K
L
K
F
S
Q
F
L
E
T
E
Y
Site 39
Y554
S
Q
F
L
E
T
E
Y
K
V
K
I
N
P
S
Site 40
S562
K
V
K
I
N
P
S
S
M
F
D
V
Q
V
K
Site 41
Y574
Q
V
K
R
I
H
E
Y
K
R
Q
L
L
N
C
Site 42
T586
L
N
C
L
H
V
I
T
M
Y
N
R
I
K
K
Site 43
Y588
C
L
H
V
I
T
M
Y
N
R
I
K
K
D
P
Site 44
S626
M
I
I
K
L
I
T
S
V
A
D
V
V
N
N
Site 45
S668
T
D
L
S
E
Q
I
S
T
A
G
T
E
A
S
Site 46
T672
E
Q
I
S
T
A
G
T
E
A
S
G
T
G
N
Site 47
S675
S
T
A
G
T
E
A
S
G
T
G
N
M
K
F
Site 48
T677
A
G
T
E
A
S
G
T
G
N
M
K
F
M
L
Site 49
Y727
A
A
L
D
K
K
G
Y
E
A
K
E
Y
Y
E
Site 50
Y732
K
G
Y
E
A
K
E
Y
Y
E
A
L
P
E
L
Site 51
Y733
G
Y
E
A
K
E
Y
Y
E
A
L
P
E
L
K
Site 52
S752
Q
I
D
N
G
F
F
S
P
K
Q
P
D
L
F
Site 53
Y778
R
F
K
V
F
A
D
Y
E
A
Y
V
K
C
Q
Site 54
Y781
V
F
A
D
Y
E
A
Y
V
K
C
Q
D
K
V
Site 55
Y792
Q
D
K
V
S
Q
L
Y
M
N
P
K
A
W
N
Site 56
S809
V
L
K
N
I
A
A
S
G
K
F
S
S
D
R
Site 57
S813
I
A
A
S
G
K
F
S
S
D
R
T
I
K
E
Site 58
S814
A
A
S
G
K
F
S
S
D
R
T
I
K
E
Y
Site 59
Y821
S
D
R
T
I
K
E
Y
A
Q
N
I
W
N
V
Site 60
S831
N
I
W
N
V
E
P
S
D
L
K
I
S
L
S
Site 61
S836
E
P
S
D
L
K
I
S
L
S
N
E
S
N
K
Site 62
S838
S
D
L
K
I
S
L
S
N
E
S
N
K
V
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation