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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LPL
Full Name:
Lipoprotein lipase
Alias:
Type:
Mass (Da):
53144
Number AA:
475
UniProt ID:
P06858
International Prot ID:
IPI00027847
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005886
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0001871
GO:0003824
GO:0004091
PhosphoSite+
KinaseNET
Biological Process:
GO:0003008
GO:0003013
GO:0006629
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
T
L
A
V
W
L
Q
S
L
T
A
S
R
G
G
Site 2
T19
A
V
W
L
Q
S
L
T
A
S
R
G
G
V
A
Site 3
S21
W
L
Q
S
L
T
A
S
R
G
G
V
A
A
A
Site 4
S39
R
D
F
I
D
I
E
S
K
F
A
L
R
T
P
Site 5
T45
E
S
K
F
A
L
R
T
P
E
D
T
A
E
D
Site 6
T49
A
L
R
T
P
E
D
T
A
E
D
T
C
H
L
Site 7
T53
P
E
D
T
A
E
D
T
C
H
L
I
P
G
V
Site 8
T66
G
V
A
E
S
V
A
T
C
H
F
N
H
S
S
Site 9
T75
H
F
N
H
S
S
K
T
F
M
V
I
H
G
W
Site 10
Y88
G
W
T
V
T
G
M
Y
E
S
W
V
P
K
L
Site 11
Y100
P
K
L
V
A
A
L
Y
K
R
E
P
D
S
N
Site 12
S106
L
Y
K
R
E
P
D
S
N
V
I
V
V
D
W
Site 13
Y121
L
S
R
A
Q
E
H
Y
P
V
S
A
G
Y
T
Site 14
S124
A
Q
E
H
Y
P
V
S
A
G
Y
T
K
L
V
Site 15
Y148
W
M
E
E
E
F
N
Y
P
L
D
N
V
H
L
Site 16
S170
H
A
A
G
I
A
G
S
L
T
N
K
K
V
N
Site 17
T172
A
G
I
A
G
S
L
T
N
K
K
V
N
R
I
Site 18
T180
N
K
K
V
N
R
I
T
G
L
D
P
A
G
P
Site 19
Y191
P
A
G
P
N
F
E
Y
A
E
A
P
S
R
L
Site 20
S196
F
E
Y
A
E
A
P
S
R
L
S
P
D
D
A
Site 21
S199
A
E
A
P
S
R
L
S
P
D
D
A
D
F
V
Site 22
T211
D
F
V
D
V
L
H
T
F
T
R
G
S
P
G
Site 23
S216
L
H
T
F
T
R
G
S
P
G
R
S
I
G
I
Site 24
S220
T
R
G
S
P
G
R
S
I
G
I
Q
K
P
V
Site 25
Y233
P
V
G
H
V
D
I
Y
P
N
G
G
T
F
Q
Site 26
S267
V
D
Q
L
V
K
C
S
H
E
R
S
I
H
L
Site 27
S271
V
K
C
S
H
E
R
S
I
H
L
F
I
D
S
Site 28
S278
S
I
H
L
F
I
D
S
L
L
N
E
E
N
P
Site 29
S286
L
L
N
E
E
N
P
S
K
A
Y
R
C
S
S
Site 30
S292
P
S
K
A
Y
R
C
S
S
K
E
A
F
E
K
Site 31
S293
S
K
A
Y
R
C
S
S
K
E
A
F
E
K
G
Site 32
S326
K
V
R
A
K
R
S
S
K
M
Y
L
K
T
R
Site 33
Y329
A
K
R
S
S
K
M
Y
L
K
T
R
S
Q
M
Site 34
T332
S
S
K
M
Y
L
K
T
R
S
Q
M
P
Y
K
Site 35
Y338
K
T
R
S
Q
M
P
Y
K
V
F
H
Y
Q
V
Site 36
Y343
M
P
Y
K
V
F
H
Y
Q
V
K
I
H
F
S
Site 37
S350
Y
Q
V
K
I
H
F
S
G
T
E
S
E
T
H
Site 38
S354
I
H
F
S
G
T
E
S
E
T
H
T
N
Q
A
Site 39
T358
G
T
E
S
E
T
H
T
N
Q
A
F
E
I
S
Site 40
S365
T
N
Q
A
F
E
I
S
L
Y
G
T
V
A
E
Site 41
Y367
Q
A
F
E
I
S
L
Y
G
T
V
A
E
S
E
Site 42
T379
E
S
E
N
I
P
F
T
L
P
E
V
S
T
N
Site 43
S384
P
F
T
L
P
E
V
S
T
N
K
T
Y
S
F
Site 44
T388
P
E
V
S
T
N
K
T
Y
S
F
L
I
Y
T
Site 45
Y394
K
T
Y
S
F
L
I
Y
T
E
V
D
I
G
E
Site 46
Y414
L
K
W
K
S
D
S
Y
F
S
W
S
D
W
W
Site 47
T438
I
R
V
K
A
G
E
T
Q
K
K
V
I
F
C
Site 48
S446
Q
K
K
V
I
F
C
S
R
E
K
V
S
H
L
Site 49
S469
F
V
K
C
H
D
K
S
L
N
K
K
S
G
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation