PhosphoNET

           
Protein Info 
   
Short Name:  TPO
Full Name:  Thyroid peroxidase
Alias: 
Type: 
Mass (Da):  102963
Number AA:  933
UniProt ID:  P07202
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T561QLMNEELTERLFVLS
Site 2T874STVICRWTRTGTKST
Site 3T876VICRWTRTGTKSTLP
Site 4T878CRWTRTGTKSTLPIS
Site 5S880WTRTGTKSTLPISET
Site 6T881TRTGTKSTLPISETG
Site 7S885TKSTLPISETGGGTP
Site 8T887STLPISETGGGTPEL
Site 9T891ISETGGGTPELRCGK
Site 10S905KHQAVGTSPQRAAAQ
Site 11S914QRAAAQDSEQESAGM
Site 12S918AQDSEQESAGMEGRD
Site 13T926AGMEGRDTHRLPRAL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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