PhosphoNET

           
Protein Info 
   
Short Name:  KLK3
Full Name:  Prostate-specific antigen
Alias:  Gamma-seminoprotein;Kallikrein-3;P-30 antigen;Semenogelase
Type: 
Mass (Da):  28741
Number AA:  261
UniProt ID:  P07288
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S71AHCIRNKSVILLGRH
Site 2T86SLFHPEDTGQVFQVS
Site 3S93TGQVFQVSHSFPHPL
Site 4S95QVFQVSHSFPHPLYD
Site 5Y101HSFPHPLYDMSLLKN
Site 6S104PHPLYDMSLLKNRFL
Site 7S117FLRPGDDSSHDLMLL
Site 8S118LRPGDDSSHDLMLLR
Site 9S127DLMLLRLSEPAELTD
Site 10T133LSEPAELTDAVKVMD
Site 11T143VKVMDLPTQEPALGT
Site 12S155LGTTCYASGWGSIEP
Site 13S159CYASGWGSIEPEEFL
Site 14T167IEPEEFLTPKKLQCV
Site 15T203MLCAGRWTGGKSTCS
Site 16S207GRWTGGKSTCSGDSG
Site 17T208RWTGGKSTCSGDSGG
Site 18S210TGGKSTCSGDSGGPL
Site 19S213KSTCSGDSGGPLVCN
Site 20T227NGVLQGITSWGSEPC
Site 21S231QGITSWGSEPCALPE
Site 22S241CALPERPSLYTKVVH
Site 23Y243LPERPSLYTKVVHYR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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