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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C8B
Full Name:
Complement component C8 beta chain
Alias:
CO8B; Complement component 8 subunit beta; Complement component 8, beta; Complement component 8, beta polypeptide; Complement component C8 beta chain; MGC163447
Type:
Mass (Da):
67047
Number AA:
591
UniProt ID:
P07358
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005579
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006957
GO:0006958
GO:0019835
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
G
C
L
S
L
P
G
S
R
G
E
R
P
H
S
Site 2
S37
S
R
G
E
R
P
H
S
F
G
S
N
A
V
N
Site 3
S40
E
R
P
H
S
F
G
S
N
A
V
N
K
S
F
Site 4
S46
G
S
N
A
V
N
K
S
F
A
K
S
R
Q
M
Site 5
S50
V
N
K
S
F
A
K
S
R
Q
M
R
S
V
D
Site 6
S55
A
K
S
R
Q
M
R
S
V
D
V
T
L
M
P
Site 7
Y86
C
Q
K
K
R
Y
R
Y
A
Y
L
L
Q
P
S
Site 8
Y88
K
K
R
Y
R
Y
A
Y
L
L
Q
P
S
Q
F
Site 9
T112
K
E
V
E
D
C
V
T
N
R
P
C
R
S
Q
Site 10
S118
V
T
N
R
P
C
R
S
Q
V
R
C
E
G
F
Site 11
T130
E
G
F
V
C
A
Q
T
G
R
C
V
N
R
R
Site 12
Y159
E
A
N
C
R
R
I
Y
K
K
C
Q
H
E
M
Site 13
Y169
C
Q
H
E
M
D
Q
Y
W
G
I
G
S
L
A
Site 14
Y195
G
P
V
L
D
H
R
Y
Y
A
G
G
C
S
P
Site 15
Y196
P
V
L
D
H
R
Y
Y
A
G
G
C
S
P
H
Site 16
Y204
A
G
G
C
S
P
H
Y
I
L
N
T
R
F
R
Site 17
T208
S
P
H
Y
I
L
N
T
R
F
R
K
P
Y
N
Site 18
Y214
N
T
R
F
R
K
P
Y
N
V
E
S
Y
T
P
Site 19
S218
R
K
P
Y
N
V
E
S
Y
T
P
Q
T
Q
G
Site 20
T220
P
Y
N
V
E
S
Y
T
P
Q
T
Q
G
K
Y
Site 21
Y227
T
P
Q
T
Q
G
K
Y
E
F
I
L
K
E
Y
Site 22
Y234
Y
E
F
I
L
K
E
Y
E
S
Y
S
D
F
E
Site 23
S236
F
I
L
K
E
Y
E
S
Y
S
D
F
E
R
N
Site 24
Y237
I
L
K
E
Y
E
S
Y
S
D
F
E
R
N
V
Site 25
S238
L
K
E
Y
E
S
Y
S
D
F
E
R
N
V
T
Site 26
T245
S
D
F
E
R
N
V
T
E
K
M
A
S
K
S
Site 27
S250
N
V
T
E
K
M
A
S
K
S
G
F
S
F
G
Site 28
S252
T
E
K
M
A
S
K
S
G
F
S
F
G
F
K
Site 29
S269
G
I
F
E
L
G
I
S
S
Q
S
D
R
G
K
Site 30
S270
I
F
E
L
G
I
S
S
Q
S
D
R
G
K
H
Site 31
S272
E
L
G
I
S
S
Q
S
D
R
G
K
H
Y
I
Site 32
Y278
Q
S
D
R
G
K
H
Y
I
R
R
T
K
R
F
Site 33
T282
G
K
H
Y
I
R
R
T
K
R
F
S
H
T
K
Site 34
S286
I
R
R
T
K
R
F
S
H
T
K
S
V
F
L
Site 35
T288
R
T
K
R
F
S
H
T
K
S
V
F
L
H
A
Site 36
S290
K
R
F
S
H
T
K
S
V
F
L
H
A
R
S
Site 37
S297
S
V
F
L
H
A
R
S
D
L
E
V
A
H
Y
Site 38
Y304
S
D
L
E
V
A
H
Y
K
L
K
P
R
S
L
Site 39
S329
K
R
L
P
L
E
Y
S
Y
G
E
Y
R
D
L
Site 40
Y333
L
E
Y
S
Y
G
E
Y
R
D
L
F
R
D
F
Site 41
T342
D
L
F
R
D
F
G
T
H
Y
I
T
E
A
V
Site 42
T346
D
F
G
T
H
Y
I
T
E
A
V
L
G
G
I
Site 43
Y370
E
A
M
E
R
G
D
Y
T
L
N
N
V
H
A
Site 44
T371
A
M
E
R
G
D
Y
T
L
N
N
V
H
A
C
Site 45
T418
K
D
R
N
K
R
D
T
M
V
E
D
L
V
V
Site 46
T436
G
G
A
S
E
H
I
T
T
L
A
Y
Q
E
L
Site 47
T437
G
A
S
E
H
I
T
T
L
A
Y
Q
E
L
P
Site 48
Y471
K
V
K
V
E
P
L
Y
E
L
V
T
A
T
D
Site 49
T475
E
P
L
Y
E
L
V
T
A
T
D
F
A
Y
S
Site 50
Y481
V
T
A
T
D
F
A
Y
S
S
T
V
R
Q
N
Site 51
S483
A
T
D
F
A
Y
S
S
T
V
R
Q
N
M
K
Site 52
T484
T
D
F
A
Y
S
S
T
V
R
Q
N
M
K
Q
Site 53
S501
E
E
F
Q
K
E
V
S
S
C
H
C
A
P
C
Site 54
S537
Q
G
L
A
C
E
V
S
Y
R
K
N
T
P
I
Site 55
T542
E
V
S
Y
R
K
N
T
P
I
D
G
K
W
N
Site 56
S558
W
S
N
W
S
S
C
S
G
R
R
K
T
R
Q
Site 57
T563
S
C
S
G
R
R
K
T
R
Q
R
Q
C
N
N
Site 58
S578
P
P
P
Q
N
G
G
S
P
C
S
G
P
A
S
Site 59
S581
Q
N
G
G
S
P
C
S
G
P
A
S
E
T
L
Site 60
S585
S
P
C
S
G
P
A
S
E
T
L
D
C
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation