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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HNRNPC
Full Name:
Heterogeneous nuclear ribonucleoproteins C1/C2
Alias:
Heterogeneous nuclear ribonucleoprotein C (C1/C2); HnRNP C1 / hnRNP C2; HnRNP-C1/C2; HNRPC; ROC
Type:
RNA binding protein
Mass (Da):
33670
Number AA:
306
UniProt ID:
P07910
International Prot ID:
IPI00477313
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
S
N
V
T
N
K
T
D
P
R
S
M
N
S
Site 2
S13
T
N
K
T
D
P
R
S
M
N
S
R
V
F
I
Site 3
S31
N
T
L
V
V
K
K
S
D
V
E
A
I
F
S
Site 4
Y57
K
G
F
A
F
V
Q
Y
V
N
E
R
N
A
R
Site 5
S100
G
K
A
G
V
K
R
S
A
A
E
M
Y
G
S
Site 6
Y105
K
R
S
A
A
E
M
Y
G
S
V
T
E
H
P
Site 7
S107
S
A
A
E
M
Y
G
S
V
T
E
H
P
S
P
Site 8
T109
A
E
M
Y
G
S
V
T
E
H
P
S
P
S
P
Site 9
S113
G
S
V
T
E
H
P
S
P
S
P
L
L
S
S
Site 10
S115
V
T
E
H
P
S
P
S
P
L
L
S
S
S
F
Site 11
S119
P
S
P
S
P
L
L
S
S
S
F
D
L
D
Y
Site 12
S120
S
P
S
P
L
L
S
S
S
F
D
L
D
Y
D
Site 13
S121
P
S
P
L
L
S
S
S
F
D
L
D
Y
D
F
Site 14
Y126
S
S
S
F
D
L
D
Y
D
F
Q
R
D
Y
Y
Site 15
Y132
D
Y
D
F
Q
R
D
Y
Y
D
R
M
Y
S
Y
Site 16
Y133
Y
D
F
Q
R
D
Y
Y
D
R
M
Y
S
Y
P
Site 17
Y137
R
D
Y
Y
D
R
M
Y
S
Y
P
A
R
V
P
Site 18
S138
D
Y
Y
D
R
M
Y
S
Y
P
A
R
V
P
P
Site 19
Y139
Y
Y
D
R
M
Y
S
Y
P
A
R
V
P
P
P
Site 20
S156
I
A
R
A
V
V
P
S
K
R
Q
R
V
S
G
Site 21
S162
P
S
K
R
Q
R
V
S
G
N
T
S
R
R
G
Site 22
T165
R
Q
R
V
S
G
N
T
S
R
R
G
K
S
G
Site 23
S166
Q
R
V
S
G
N
T
S
R
R
G
K
S
G
F
Site 24
S171
N
T
S
R
R
G
K
S
G
F
N
S
K
S
G
Site 25
S175
R
G
K
S
G
F
N
S
K
S
G
Q
R
G
S
Site 26
S177
K
S
G
F
N
S
K
S
G
Q
R
G
S
S
K
Site 27
S182
S
K
S
G
Q
R
G
S
S
K
S
G
K
L
K
Site 28
S183
K
S
G
Q
R
G
S
S
K
S
G
K
L
K
G
Site 29
S185
G
Q
R
G
S
S
K
S
G
K
L
K
G
D
D
Site 30
S209
Q
I
K
Q
K
V
D
S
L
L
E
N
L
E
K
Site 31
S222
E
K
I
E
K
E
Q
S
K
Q
A
V
E
M
K
Site 32
S233
V
E
M
K
N
D
K
S
E
E
E
Q
S
S
S
Site 33
S238
D
K
S
E
E
E
Q
S
S
S
S
V
K
K
D
Site 34
S239
K
S
E
E
E
Q
S
S
S
S
V
K
K
D
E
Site 35
S240
S
E
E
E
Q
S
S
S
S
V
K
K
D
E
T
Site 36
S241
E
E
E
Q
S
S
S
S
V
K
K
D
E
T
N
Site 37
T247
S
S
V
K
K
D
E
T
N
V
K
M
E
S
E
Site 38
S253
E
T
N
V
K
M
E
S
E
G
G
A
D
D
S
Site 39
S260
S
E
G
G
A
D
D
S
A
E
E
G
D
L
L
Site 40
S299
E
G
E
D
D
R
D
S
A
N
G
E
D
D
S
Site 41
S306
S
A
N
G
E
D
D
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation