PhosphoNET

           
Protein Info 
   
Short Name:  SP1
Full Name:  Transcription factor Sp1
Alias:  Sp1 transcription factor; Transcription factor SP1; TSFP1
Type:  Transcription protein
Mass (Da):  80693
Number AA:  785
UniProt ID:  P08047
International Prot ID:  IPI00465152
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0003702  GO:0042826  GO:0010843 PhosphoSite+ KinaseNET
Biological Process:  GO:0044419  GO:0045817  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSDQDHSMD
Site 2S7_MSDQDHSMDEMTAV
Site 3T12DHSMDEMTAVVKIEK
Site 4S36GNGGGAFSQARSSST
Site 5S40GAFSQARSSSTGSSS
Site 6S41AFSQARSSSTGSSSS
Site 7S42FSQARSSSTGSSSST
Site 8T43SQARSSSTGSSSSTG
Site 9S45ARSSSTGSSSSTGGG
Site 10S46RSSSTGSSSSTGGGG
Site 11S47SSSTGSSSSTGGGGQ
Site 12S48SSTGSSSSTGGGGQE
Site 13T49STGSSSSTGGGGQES
Site 14S56TGGGGQESQPSPLAL
Site 15S59GGQESQPSPLALLAA
Site 16S69ALLAATCSRIESPNE
Site 17S73ATCSRIESPNENSNN
Site 18S78IESPNENSNNSQGPS
Site 19S81PNENSNNSQGPSQSG
Site 20S85SNNSQGPSQSGGTGE
Site 21T96GTGELDLTATQLSQG
Site 22T98GELDLTATQLSQGAN
Site 23S101DLTATQLSQGANGWQ
Site 24S111ANGWQIISSSSGATP
Site 25S112NGWQIISSSSGATPT
Site 26S113GWQIISSSSGATPTS
Site 27T117ISSSSGATPTSKEQS
Site 28S120SSGATPTSKEQSGSS
Site 29S124TPTSKEQSGSSTNGS
Site 30S126TSKEQSGSSTNGSNG
Site 31S127SKEQSGSSTNGSNGS
Site 32T128KEQSGSSTNGSNGSE
Site 33S131SGSSTNGSNGSESSK
Site 34S134STNGSNGSESSKNRT
Site 35S137GSNGSESSKNRTVSG
Site 36T141SESSKNRTVSGGQYV
Site 37S143SSKNRTVSGGQYVVA
Site 38Y147RTVSGGQYVVAAAPN
Site 39Y173GVMPNIQYQVIPQFQ
Site 40T216GANQQIITNRGSGGN
Site 41T254SGQTQYVTNVPVALN
Site 42T278SVSAATLTPSSQAVT
Site 43T285TPSSQAVTISSSGSQ
Site 44S287SSQAVTISSSGSQES
Site 45S288SQAVTISSSGSQESG
Site 46S289QAVTISSSGSQESGS
Site 47S291VTISSSGSQESGSQP
Site 48S294SSSGSQESGSQPVTS
Site 49S296SGSQESGSQPVTSGT
Site 50T300ESGSQPVTSGTTISS
Site 51S301SGSQPVTSGTTISSA
Site 52T303SQPVTSGTTISSASL
Site 53S307TSGTTISSASLVSSQ
Site 54S312ISSASLVSSQASSSS
Site 55S313SSASLVSSQASSSSF
Site 56S316SLVSSQASSSSFFTN
Site 57S317LVSSQASSSSFFTNA
Site 58S318VSSQASSSSFFTNAN
Site 59S319SSQASSSSFFTNANS
Site 60T322ASSSSFFTNANSYST
Site 61S326SFFTNANSYSTTTTT
Site 62S328FTNANSYSTTTTTSN
Site 63T330NANSYSTTTTTSNMG
Site 64T332NSYSTTTTTSNMGIM
Site 65T342NMGIMNFTTSGSSGT
Site 66T343MGIMNFTTSGSSGTN
Site 67S344GIMNFTTSGSSGTNS
Site 68S351SGSSGTNSQGQTPQR
Site 69T355GTNSQGQTPQRVSGL
Site 70S360GQTPQRVSGLQGSDA
Site 71S365RVSGLQGSDALNIQQ
Site 72T375LNIQQNQTSGGSLQA
Site 73S376NIQQNQTSGGSLQAG
Site 74S421ALQAAPLSGQTFTTQ
Site 75T427LSGQTFTTQAISQET
Site 76S431TFTTQAISQETLQNL
Site 77T453SGPIIIRTPTVGPNG
Site 78S463VGPNGQVSWQTLQLQ
Site 79T483NPQAQTITLAPMQGV
Site 80S491LAPMQGVSLGQTSSS
Site 81T495QGVSLGQTSSSNTTL
Site 82S497VSLGQTSSSNTTLTP
Site 83S498SLGQTSSSNTTLTPI
Site 84T501QTSSSNTTLTPIASA
Site 85T503SSSNTTLTPIASAAS
Site 86S524TVNAAQLSSMPGLQT
Site 87T579GDGIHDDTAGGEEGE
Site 88S588GGEEGENSPDAQPQA
Site 89T599QPQAGRRTRREACTC
Site 90T605RTRREACTCPYCKDS
Site 91Y608REACTCPYCKDSEGR
Site 92S612TCPYCKDSEGRGSGD
Site 93S617KDSEGRGSGDPGKKK
Site 94Y637IQGCGKVYGKTSHLR
Site 95T640CGKVYGKTSHLRAHL
Site 96S641GKVYGKTSHLRAHLR
Site 97T651RAHLRWHTGERPFMC
Site 98T668SYCGKRFTRSDELQR
Site 99S670CGKRFTRSDELQRHK
Site 100T679ELQRHKRTHTGEKKF
Site 101T681QRHKRTHTGEKKFAC
Site 102S698CPKRFMRSDHLSKHI
Site 103S702FMRSDHLSKHIKTHQ
Site 104T707HLSKHIKTHQNKKGG
Site 105S728VGTLPLDSGAGSEGS
Site 106S732PLDSGAGSEGSGTAT
Site 107S735SGAGSEGSGTATPSA
Site 108T739SEGSGTATPSALITT
Site 109S777MQVADLQSINISGNG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation