PhosphoNET

           
Protein Info 
   
Short Name:  NGFR
Full Name:  Tumor necrosis factor receptor superfamily member 16
Alias:  CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; Nerve growth factor receptor; NGF receptor; P75 ICD; P75NTR; TNFR superfamily, member 16; TNFRSF16; TNR16; Tumor necrosis factor receptor superfamily member 16
Type:  Receptor, low affinity for NGF, BDNF, NT3 and NT4
Mass (Da):  45183
Number AA:  427
UniProt ID:  P08138
International Prot ID:  IPI00027436
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005768  GO:0005887 Uniprot OncoNet
Molecular Function:  GO:0004888     PhosphoSite+ KinaseNET
Biological Process:  GO:0006916  GO:0006915  GO:0008624 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S277IAFKRWNSCKQNKQG
Site 2T293NSRPVNQTPPPEGEK
Site 3S303PEGEKLHSDSGISVD
Site 4S305GEKLHSDSGISVDSQ
Site 5S308LHSDSGISVDSQSLH
Site 6S311DSGISVDSQSLHDQQ
Site 7S313GISVDSQSLHDQQPH
Site 8T321LHDQQPHTQTASGQA
Site 9Y336LKGDGGLYSSLPPAK
Site 10S337KGDGGLYSSLPPAKR
Site 11S338GDGGLYSSLPPAKRE
Site 12T358LNGSAGDTWRHLAGE
Site 13T377PEHIDSFTHEACPVR
Site 14S416QRADLVESLCSESTA
Site 15S419DLVESLCSESTATSP
Site 16S421VESLCSESTATSPV_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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