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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC3A2
Full Name:
4F2 cell-surface antigen heavy chain
Alias:
4F2; 4F2 heavy chain; 4F2HC; 4T2HC; Antigen defined by monoclonal antibody 4F2; Antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43; CD98; CD98 heavy chain; CD98HC; Heavy chain; Lymphocyte activation antigen 4F2 large subunit; MDU1; Monoclonal antibody 44D7; NACAE; Solute carrier family 3 (activators of dibasic and neutral amino acid transport) member 2; Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Type:
Transporter
Mass (Da):
67994
Number AA:
630
UniProt ID:
P08195
International Prot ID:
IPI00027493
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0016021
GO:0042470
Uniprot
OncoNet
Molecular Function:
GO:0005432
GO:0003824
GO:0043169
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0005975
GO:0016049
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
L
Q
P
P
E
A
S
I
A
V
V
S
I
A
Site 2
S22
I
P
R
Q
L
P
G
S
H
S
E
A
G
V
Q
Site 3
S24
R
Q
L
P
G
S
H
S
E
A
G
V
Q
G
L
Site 4
S37
G
L
S
A
G
D
D
S
E
L
G
S
H
C
V
Site 5
S41
G
D
D
S
E
L
G
S
H
C
V
A
Q
T
G
Site 6
S60
A
S
G
D
P
L
P
S
A
S
Q
N
A
E
M
Site 7
S62
G
D
P
L
P
S
A
S
Q
N
A
E
M
I
E
Site 8
T70
Q
N
A
E
M
I
E
T
G
S
D
C
V
T
Q
Site 9
S72
A
E
M
I
E
T
G
S
D
C
V
T
Q
A
G
Site 10
S93
S
D
P
P
A
L
A
S
K
N
A
E
V
T
G
Site 11
T101
K
N
A
E
V
T
G
T
M
S
Q
D
T
E
V
Site 12
S103
A
E
V
T
G
T
M
S
Q
D
T
E
V
D
M
Site 13
T106
T
G
T
M
S
Q
D
T
E
V
D
M
K
E
V
Site 14
S134
A
A
S
G
A
A
M
S
L
A
G
A
E
K
N
Site 15
T162
A
A
A
A
A
K
F
T
G
L
S
K
E
E
L
Site 16
S165
A
A
K
F
T
G
L
S
K
E
E
L
L
K
V
Site 17
S175
E
L
L
K
V
A
G
S
P
G
W
V
R
T
R
Site 18
S406
L
L
T
S
S
Y
L
S
D
S
G
S
T
G
E
Site 19
S408
T
S
S
Y
L
S
D
S
G
S
T
G
E
H
T
Site 20
S410
S
Y
L
S
D
S
G
S
T
G
E
H
T
K
S
Site 21
S527
L
S
L
F
R
R
L
S
D
Q
R
S
K
E
R
Site 22
S531
R
R
L
S
D
Q
R
S
K
E
R
S
L
L
H
Site 23
S607
Q
P
G
R
E
E
G
S
P
L
E
L
E
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation