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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SRPR
Full Name:
Signal recognition particle receptor subunit alpha
Alias:
Docking protein alpha; DP-alpha; Signal recognition particle receptor (docking protein); Signal recognition particle receptor alpha subunit; Sralpha; SR-alpha; SRP-alpha
Type:
Endoplasmic reticulum
Mass (Da):
69811
Number AA:
638
UniProt ID:
P08240
International Prot ID:
IPI00784124
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0019898
GO:0016021
GO:0005785
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006614
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S46
Q
E
R
G
G
N
N
S
F
T
H
E
A
L
T
Site 2
T48
R
G
G
N
N
S
F
T
H
E
A
L
T
L
K
Site 3
Y78
Q
K
I
L
T
L
T
Y
V
D
K
L
I
D
D
Site 4
Y94
H
R
L
F
R
D
K
Y
R
T
E
I
Q
Q
Q
Site 5
T96
L
F
R
D
K
Y
R
T
E
I
Q
Q
Q
S
A
Site 6
S102
R
T
E
I
Q
Q
Q
S
A
L
S
L
L
N
G
Site 7
S127
L
L
R
E
A
E
E
S
S
K
I
R
A
P
T
Site 8
S128
L
R
E
A
E
E
S
S
K
I
R
A
P
T
T
Site 9
T134
S
S
K
I
R
A
P
T
T
M
K
K
F
E
D
Site 10
T135
S
K
I
R
A
P
T
T
M
K
K
F
E
D
S
Site 11
S151
K
A
K
K
P
V
R
S
M
I
E
T
R
G
E
Site 12
T155
P
V
R
S
M
I
E
T
R
G
E
K
P
K
E
Site 13
S177
K
G
A
K
K
E
G
S
D
G
P
L
A
T
S
Site 14
T183
G
S
D
G
P
L
A
T
S
K
P
V
P
A
E
Site 15
S184
S
D
G
P
L
A
T
S
K
P
V
P
A
E
K
Site 16
S205
P
E
N
G
V
E
L
S
K
E
E
L
I
R
R
Site 17
S228
H
G
R
G
M
E
K
S
N
K
S
T
K
S
D
Site 18
S231
G
M
E
K
S
N
K
S
T
K
S
D
A
P
K
Site 19
T232
M
E
K
S
N
K
S
T
K
S
D
A
P
K
E
Site 20
S234
K
S
N
K
S
T
K
S
D
A
P
K
E
K
G
Site 21
Y261
A
N
K
E
V
L
D
Y
S
T
P
T
T
N
G
Site 22
S262
N
K
E
V
L
D
Y
S
T
P
T
T
N
G
T
Site 23
T263
K
E
V
L
D
Y
S
T
P
T
T
N
G
T
P
Site 24
T266
L
D
Y
S
T
P
T
T
N
G
T
P
E
A
A
Site 25
T269
S
T
P
T
T
N
G
T
P
E
A
A
L
S
E
Site 26
S275
G
T
P
E
A
A
L
S
E
D
I
N
L
I
R
Site 27
T284
D
I
N
L
I
R
G
T
G
S
G
G
Q
L
Q
Site 28
S286
N
L
I
R
G
T
G
S
G
G
Q
L
Q
D
L
Site 29
S296
Q
L
Q
D
L
D
C
S
S
S
D
D
E
G
A
Site 30
S297
L
Q
D
L
D
C
S
S
S
D
D
E
G
A
A
Site 31
S298
Q
D
L
D
C
S
S
S
D
D
E
G
A
A
Q
Site 32
S307
D
E
G
A
A
Q
N
S
T
K
P
S
A
T
K
Site 33
S311
A
Q
N
S
T
K
P
S
A
T
K
G
T
L
G
Site 34
S330
M
L
K
G
L
V
G
S
K
S
L
S
R
E
D
Site 35
S332
K
G
L
V
G
S
K
S
L
S
R
E
D
M
E
Site 36
S334
L
V
G
S
K
S
L
S
R
E
D
M
E
S
V
Site 37
S340
L
S
R
E
D
M
E
S
V
L
D
K
M
R
D
Site 38
S383
G
T
F
S
T
V
T
S
T
V
K
Q
A
L
Q
Site 39
Y419
A
Q
R
R
Q
R
P
Y
V
V
T
F
C
G
V
Site 40
S432
G
V
N
G
V
G
K
S
T
N
L
A
K
I
S
Site 41
T467
G
A
V
E
Q
L
R
T
H
T
R
R
L
S
A
Site 42
T469
V
E
Q
L
R
T
H
T
R
R
L
S
A
L
H
Site 43
S473
R
T
H
T
R
R
L
S
A
L
H
P
P
E
K
Site 44
S574
N
R
A
L
A
D
H
S
M
A
Q
T
P
R
L
Site 45
T578
A
D
H
S
M
A
Q
T
P
R
L
I
D
G
I
Site 46
S625
Q
T
Y
C
D
L
R
S
L
N
A
K
A
V
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation