PhosphoNET

           
Protein Info 
   
Short Name:  SYP
Full Name:  Synaptophysin
Alias:  Major synaptic vesicle protein p38; SYPH
Type:  Vesicle protein
Mass (Da):  33845
Number AA:  313
UniProt ID:  P08247
International Prot ID:  IPI00027770
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030054  GO:0030285  GO:0019717 Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0015485  GO:0005215 PhosphoSite+ KinaseNET
Biological Process:  GO:0048169  GO:0048172  GO:0016188 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S54YSGELQLSVDCANKT
Site 2T61SVDCANKTESDLSIE
Site 3S66NKTESDLSIEVEFEY
Site 4Y73SIEVEFEYPFRLHQV
Site 5Y81PFRLHQVYFDAPTCR
Site 6T86QVYFDAPTCRGGTTK
Site 7S165SAWAKGLSDVKMATD
Site 8T186EMPVCRQTGNTCKEL
Site 9T198KELRDPVTSGLNTSV
Site 10S199ELRDPVTSGLNTSVV
Site 11Y250QPAPGDAYGDAGYGQ
Site 12Y255DAYGDAGYGQGPGGY
Site 13Y262YGQGPGGYGPQDSYG
Site 14S267GGYGPQDSYGPQGGY
Site 15Y268GYGPQDSYGPQGGYQ
Site 16Y274SYGPQGGYQPDYGQP
Site 17Y278QGGYQPDYGQPAGSG
Site 18S284DYGQPAGSGGSGYGP
Site 19Y289AGSGGSGYGPQGDYG
Site 20Y295GYGPQGDYGQQGYGP
Site 21S308GPQGAPTSFSNQM__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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