KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SYP
Full Name:
Synaptophysin
Alias:
Major synaptic vesicle protein p38; SYPH
Type:
Vesicle protein
Mass (Da):
33845
Number AA:
313
UniProt ID:
P08247
International Prot ID:
IPI00027770
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0030285
GO:0019717
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0015485
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0048169
GO:0048172
GO:0016188
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S54
Y
S
G
E
L
Q
L
S
V
D
C
A
N
K
T
Site 2
T61
S
V
D
C
A
N
K
T
E
S
D
L
S
I
E
Site 3
S66
N
K
T
E
S
D
L
S
I
E
V
E
F
E
Y
Site 4
Y73
S
I
E
V
E
F
E
Y
P
F
R
L
H
Q
V
Site 5
Y81
P
F
R
L
H
Q
V
Y
F
D
A
P
T
C
R
Site 6
T86
Q
V
Y
F
D
A
P
T
C
R
G
G
T
T
K
Site 7
S165
S
A
W
A
K
G
L
S
D
V
K
M
A
T
D
Site 8
T186
E
M
P
V
C
R
Q
T
G
N
T
C
K
E
L
Site 9
T198
K
E
L
R
D
P
V
T
S
G
L
N
T
S
V
Site 10
S199
E
L
R
D
P
V
T
S
G
L
N
T
S
V
V
Site 11
Y250
Q
P
A
P
G
D
A
Y
G
D
A
G
Y
G
Q
Site 12
Y255
D
A
Y
G
D
A
G
Y
G
Q
G
P
G
G
Y
Site 13
Y262
Y
G
Q
G
P
G
G
Y
G
P
Q
D
S
Y
G
Site 14
S267
G
G
Y
G
P
Q
D
S
Y
G
P
Q
G
G
Y
Site 15
Y268
G
Y
G
P
Q
D
S
Y
G
P
Q
G
G
Y
Q
Site 16
Y274
S
Y
G
P
Q
G
G
Y
Q
P
D
Y
G
Q
P
Site 17
Y278
Q
G
G
Y
Q
P
D
Y
G
Q
P
A
G
S
G
Site 18
S284
D
Y
G
Q
P
A
G
S
G
G
S
G
Y
G
P
Site 19
Y289
A
G
S
G
G
S
G
Y
G
P
Q
G
D
Y
G
Site 20
Y295
G
Y
G
P
Q
G
D
Y
G
Q
Q
G
Y
G
P
Site 21
S308
G
P
Q
G
A
P
T
S
F
S
N
Q
M
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation