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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COL4A2
Full Name:
Collagen alpha-2(IV) chain
Alias:
Alpha 2 type IV collagen; Canstatin; CO4A2; Collagen type IV alpha 2
Type:
Extracellular matrix
Mass (Da):
167553
Number AA:
1712
UniProt ID:
P08572
International Prot ID:
IPI00306322
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005587
Uniprot
OncoNet
Molecular Function:
GO:0005201
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030198
GO:0016525
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y54
C
S
G
G
C
Q
C
Y
P
E
K
G
G
R
G
Site 2
Y71
G
P
V
G
P
Q
G
Y
N
G
P
P
G
L
Q
Site 3
S111
D
V
G
A
R
G
V
S
G
F
P
G
A
D
G
Site 4
Y134
G
P
R
G
R
P
G
Y
D
G
C
N
G
T
Q
Site 5
T140
G
Y
D
G
C
N
G
T
Q
G
D
S
G
P
Q
Site 6
S144
C
N
G
T
Q
G
D
S
G
P
Q
G
P
P
G
Site 7
S152
G
P
Q
G
P
P
G
S
E
G
F
T
G
P
P
Site 8
T156
P
P
G
S
E
G
F
T
G
P
P
G
P
Q
G
Site 9
Y172
K
G
Q
K
G
E
P
Y
A
L
P
K
E
E
R
Site 10
Y182
P
K
E
E
R
D
R
Y
R
G
E
P
G
E
P
Site 11
Y236
G
N
R
G
L
G
F
Y
G
V
K
G
E
K
G
Site 12
S255
P
G
P
N
G
I
P
S
D
T
L
H
P
I
I
Site 13
T257
P
N
G
I
P
S
D
T
L
H
P
I
I
A
P
Site 14
T268
I
I
A
P
T
G
V
T
F
H
P
D
Q
Y
K
Site 15
Y274
V
T
F
H
P
D
Q
Y
K
G
E
K
G
S
E
Site 16
S290
E
P
G
I
R
G
I
S
L
K
G
E
E
G
I
Site 17
Y306
G
F
P
G
L
R
G
Y
P
G
L
S
G
E
K
Site 18
S310
L
R
G
Y
P
G
L
S
G
E
K
G
S
P
G
Site 19
S315
G
L
S
G
E
K
G
S
P
G
Q
K
G
S
R
Site 20
S321
G
S
P
G
Q
K
G
S
R
G
L
D
G
Y
Q
Site 21
Y327
G
S
R
G
L
D
G
Y
Q
G
P
D
G
P
R
Site 22
Y351
G
P
P
G
L
P
A
Y
S
P
H
P
S
L
A
Site 23
S352
P
P
G
L
P
A
Y
S
P
H
P
S
L
A
K
Site 24
S356
P
A
Y
S
P
H
P
S
L
A
K
G
A
R
G
Site 25
S376
G
A
Q
G
E
P
G
S
Q
G
E
P
G
D
P
Site 26
S392
L
P
G
P
P
G
L
S
I
G
D
G
D
Q
R
Site 27
Y421
D
P
G
I
P
A
L
Y
G
G
P
P
G
P
D
Site 28
S467
G
F
P
G
L
P
G
S
P
G
A
R
G
P
K
Site 29
T486
D
A
G
E
C
R
C
T
E
G
D
E
A
I
K
Site 30
S550
P
K
G
A
K
G
D
S
R
T
I
T
T
K
G
Site 31
T552
G
A
K
G
D
S
R
T
I
T
T
K
G
E
R
Site 32
T554
K
G
D
S
R
T
I
T
T
K
G
E
R
G
Q
Site 33
S576
G
M
K
G
D
D
G
S
P
G
R
D
G
L
D
Site 34
Y605
G
P
P
G
D
P
G
Y
P
G
I
P
G
T
K
Site 35
T614
G
I
P
G
T
K
G
T
P
G
E
M
G
P
P
Site 36
T655
G
P
P
G
P
A
G
T
P
G
Q
I
D
C
D
Site 37
T663
P
G
Q
I
D
C
D
T
D
V
K
R
A
V
G
Site 38
S754
G
L
P
G
P
D
G
S
P
G
P
I
G
L
P
Site 39
S810
G
P
P
G
F
R
G
S
Q
G
M
P
G
M
P
Site 40
S829
Q
P
G
L
P
G
P
S
G
Q
P
G
L
Y
G
Site 41
Y835
P
S
G
Q
P
G
L
Y
G
P
P
G
L
H
G
Site 42
T874
D
R
G
D
P
G
D
T
G
A
P
G
P
V
G
Site 43
S886
P
V
G
M
K
G
L
S
G
D
R
G
D
A
G
Site 44
S903
G
E
Q
G
H
P
G
S
P
G
F
K
G
I
D
Site 45
T915
G
I
D
G
M
P
G
T
P
G
L
K
G
D
R
Site 46
S924
G
L
K
G
D
R
G
S
P
G
M
D
G
F
Q
Site 47
S945
G
R
P
G
F
P
G
S
K
G
E
A
G
F
F
Site 48
Y1004
G
P
M
G
L
K
G
Y
L
G
A
K
G
I
Q
Site 49
S1068
G
F
P
G
F
I
G
S
R
G
D
K
G
A
P
Site 50
Y1081
A
P
G
R
A
G
L
Y
G
E
I
G
A
T
G
Site 51
T1111
G
L
K
G
E
R
G
T
T
G
I
P
G
L
K
Site 52
T1112
L
K
G
E
R
G
T
T
G
I
P
G
L
K
G
Site 53
T1151
P
P
G
L
K
G
Q
T
G
F
P
G
L
T
G
Site 54
T1157
Q
T
G
F
P
G
L
T
G
P
P
G
S
Q
G
Site 55
S1162
G
L
T
G
P
P
G
S
Q
G
E
L
G
R
I
Site 56
T1204
G
L
H
G
L
P
G
T
K
G
F
P
G
S
P
Site 57
S1210
G
T
K
G
F
P
G
S
P
G
S
D
I
H
G
Site 58
S1213
G
F
P
G
S
P
G
S
D
I
H
G
D
P
G
Site 59
S1261
G
E
R
G
P
P
G
S
P
G
L
Q
G
F
P
Site 60
T1271
L
Q
G
F
P
G
I
T
P
P
S
N
I
S
G
Site 61
S1274
F
P
G
I
T
P
P
S
N
I
S
G
A
P
G
Site 62
S1277
I
T
P
P
S
N
I
S
G
A
P
G
D
K
G
Site 63
Y1294
G
I
F
G
L
K
G
Y
R
G
P
P
G
P
P
Site 64
S1303
G
P
P
G
P
P
G
S
A
A
L
P
G
S
K
Site 65
S1309
G
S
A
A
L
P
G
S
K
G
D
T
G
N
P
Site 66
T1313
L
P
G
S
K
G
D
T
G
N
P
G
A
P
G
Site 67
T1321
G
N
P
G
A
P
G
T
P
G
T
K
G
W
A
Site 68
S1331
T
K
G
W
A
G
D
S
G
P
Q
G
R
P
G
Site 69
T1403
K
I
A
V
Q
P
G
T
V
G
P
Q
G
R
R
Site 70
S1446
P
Q
G
R
G
G
V
S
A
V
P
G
F
R
G
Site 71
S1475
G
A
P
G
R
P
G
S
P
G
L
P
G
M
P
Site 72
Y1490
G
R
S
V
S
I
G
Y
L
L
V
K
H
S
Q
Site 73
S1496
G
Y
L
L
V
K
H
S
Q
T
D
Q
E
P
M
Site 74
S1516
N
K
L
W
S
G
Y
S
L
L
Y
F
E
G
Q
Site 75
Y1519
W
S
G
Y
S
L
L
Y
F
E
G
Q
E
K
A
Site 76
Y1556
C
N
P
G
D
V
C
Y
Y
A
S
R
N
D
K
Site 77
Y1557
N
P
G
D
V
C
Y
Y
A
S
R
N
D
K
S
Site 78
S1564
Y
A
S
R
N
D
K
S
Y
W
L
S
T
T
A
Site 79
Y1565
A
S
R
N
D
K
S
Y
W
L
S
T
T
A
P
Site 80
S1568
N
D
K
S
Y
W
L
S
T
T
A
P
L
P
M
Site 81
T1569
D
K
S
Y
W
L
S
T
T
A
P
L
P
M
M
Site 82
Y1586
A
E
D
E
I
K
P
Y
I
S
R
C
S
V
C
Site 83
S1608
A
V
H
S
Q
D
V
S
I
P
H
C
P
A
G
Site 84
S1639
G
D
E
G
G
G
Q
S
L
V
S
P
G
S
C
Site 85
S1642
G
G
G
Q
S
L
V
S
P
G
S
C
L
E
D
Site 86
S1645
Q
S
L
V
S
P
G
S
C
L
E
D
F
R
A
Site 87
Y1667
G
G
R
G
T
C
H
Y
Y
A
N
K
Y
S
F
Site 88
S1683
L
T
T
I
P
E
Q
S
F
Q
G
S
P
S
A
Site 89
S1687
P
E
Q
S
F
Q
G
S
P
S
A
D
T
L
K
Site 90
S1689
Q
S
F
Q
G
S
P
S
A
D
T
L
K
A
G
Site 91
T1692
Q
G
S
P
S
A
D
T
L
K
A
G
L
I
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation