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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYC1
Full Name:
Cytochrome c1, heme protein, mitochondrial
Alias:
Complex III subunit 4;Complex III subunit IV;Cytochrome b-c1 complex subunit 4;Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit
Type:
Mass (Da):
35390
Number AA:
325
UniProt ID:
P08574
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
R
A
R
G
L
L
C
S
A
R
P
G
Q
L
P
Site 2
T41
P
G
Q
L
P
L
R
T
P
Q
A
V
A
L
S
Site 3
S48
T
P
Q
A
V
A
L
S
S
K
S
G
L
S
R
Site 4
S49
P
Q
A
V
A
L
S
S
K
S
G
L
S
R
G
Site 5
S51
A
V
A
L
S
S
K
S
G
L
S
R
G
R
K
Site 6
S54
L
S
S
K
S
G
L
S
R
G
R
K
V
M
L
Site 7
S93
D
L
E
L
H
P
P
S
Y
P
W
S
H
R
G
Site 8
Y94
L
E
L
H
P
P
S
Y
P
W
S
H
R
G
L
Site 9
S97
H
P
P
S
Y
P
W
S
H
R
G
L
L
S
S
Site 10
S103
W
S
H
R
G
L
L
S
S
L
D
H
T
S
I
Site 11
S104
S
H
R
G
L
L
S
S
L
D
H
T
S
I
R
Site 12
T108
L
L
S
S
L
D
H
T
S
I
R
R
G
F
Q
Site 13
S109
L
S
S
L
D
H
T
S
I
R
R
G
F
Q
V
Site 14
Y117
I
R
R
G
F
Q
V
Y
K
Q
V
C
A
S
C
Site 15
Y140
R
H
L
V
G
V
C
Y
T
E
D
E
A
K
E
Site 16
Y174
R
P
G
K
L
F
D
Y
F
P
K
P
Y
P
N
Site 17
Y179
F
D
Y
F
P
K
P
Y
P
N
S
E
A
A
R
Site 18
S182
F
P
K
P
Y
P
N
S
E
A
A
R
A
A
N
Site 19
S198
G
A
L
P
P
D
L
S
Y
I
V
R
A
R
H
Site 20
Y199
A
L
P
P
D
L
S
Y
I
V
R
A
R
H
G
Site 21
Y210
A
R
H
G
G
E
D
Y
V
F
S
L
L
T
G
Site 22
S213
G
G
E
D
Y
V
F
S
L
L
T
G
Y
C
E
Site 23
T223
T
G
Y
C
E
P
P
T
G
V
S
L
R
E
G
Site 24
S226
C
E
P
P
T
G
V
S
L
R
E
G
L
Y
F
Site 25
Y232
V
S
L
R
E
G
L
Y
F
N
P
Y
F
P
G
Site 26
Y236
E
G
L
Y
F
N
P
Y
F
P
G
Q
A
I
A
Site 27
T259
V
L
E
F
D
D
G
T
P
A
T
M
S
Q
I
Site 28
S264
D
G
T
P
A
T
M
S
Q
I
A
K
D
V
C
Site 29
T272
Q
I
A
K
D
V
C
T
F
L
R
W
A
S
E
Site 30
S312
T
I
K
R
H
K
W
S
V
L
K
S
R
K
L
Site 31
S316
H
K
W
S
V
L
K
S
R
K
L
A
Y
R
P
Site 32
Y321
L
K
S
R
K
L
A
Y
R
P
P
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation