PhosphoNET

           
Protein Info 
   
Short Name:  F7
Full Name:  Coagulation factor VII
Alias:  Proconvertin;Serum prothrombin conversion accelerator
Type: 
Mass (Da):  51594
Number AA:  466
UniProt ID:  P08709
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S28AGGVAKASGGETRDM
Site 2S72LEELRPGSLERECKE
Site 3S83ECKEEQCSFEEAREI
Site 4S105KLFWISYSDGDQCAS
Site 5S112SDGDQCASSPCQNGG
Site 6S113DGDQCASSPCQNGGS
Site 7S120SPCQNGGSCKDQLQS
Site 8Y161ENGGCEQYCSDHTGT
Site 9T166EQYCSDHTGTKRSCR
Site 10Y178SCRCHEGYSLLADGV
Site 11T190DGVSCTPTVEYPCGK
Site 12S207ILEKRNASKPQGRIV
Site 13S274VLGEHDLSEHDGDEQ
Site 14S282EHDGDEQSRRVAQVI
Site 15Y294QVIIPSTYVPGTTNH
Site 16T327PLCLPERTFSERTLA
Site 17T367LNVPRLMTQDCLQQS
Site 18S380QSRKVGDSPNITEYM
Site 19Y386DSPNITEYMFCAGYS
Site 20Y392EYMFCAGYSDGSKDS
Site 21S399YSDGSKDSCKGDSGG
Site 22Y412GGPHATHYRGTWYLT
Site 23T438VGHFGVYTRVSQYIE
Site 24S453WLQKLMRSEPRPGVL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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