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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT7
Full Name:
Keratin, type II cytoskeletal 7
Alias:
CK 7; CK7; Cytokeratin 7; Cytokeratin-7; K2C7; Keratin 7; Keratin, 55K type II cytoskeletal; KRT7 protein; Sarcolectin; SCL
Type:
Cytoskeletal protein
Mass (Da):
51405
Number AA:
469
UniProt ID:
P08729
International Prot ID:
IPI00306959
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0045095
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0007010
GO:0051325
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
I
H
F
S
S
P
V
Site 2
S6
_
_
M
S
I
H
F
S
S
P
V
F
T
S
R
Site 3
S7
_
M
S
I
H
F
S
S
P
V
F
T
S
R
S
Site 4
T11
H
F
S
S
P
V
F
T
S
R
S
A
A
F
S
Site 5
S14
S
P
V
F
T
S
R
S
A
A
F
S
G
R
G
Site 6
S18
T
S
R
S
A
A
F
S
G
R
G
A
Q
V
R
Site 7
S27
R
G
A
Q
V
R
L
S
S
A
R
P
G
G
L
Site 8
S28
G
A
Q
V
R
L
S
S
A
R
P
G
G
L
G
Site 9
S36
A
R
P
G
G
L
G
S
S
S
L
Y
G
L
G
Site 10
S37
R
P
G
G
L
G
S
S
S
L
Y
G
L
G
A
Site 11
S38
P
G
G
L
G
S
S
S
L
Y
G
L
G
A
S
Site 12
Y40
G
L
G
S
S
S
L
Y
G
L
G
A
S
R
P
Site 13
S45
S
L
Y
G
L
G
A
S
R
P
R
V
A
V
R
Site 14
S53
R
P
R
V
A
V
R
S
A
Y
G
G
P
V
G
Site 15
Y55
R
V
A
V
R
S
A
Y
G
G
P
V
G
A
G
Site 16
T67
G
A
G
I
R
E
V
T
I
N
Q
S
L
L
A
Site 17
S83
L
R
L
D
A
D
P
S
L
Q
R
V
R
Q
E
Site 18
S92
Q
R
V
R
Q
E
E
S
E
Q
I
K
T
L
N
Site 19
T97
E
E
S
E
Q
I
K
T
L
N
N
K
F
A
S
Site 20
S104
T
L
N
N
K
F
A
S
F
I
D
K
V
R
F
Site 21
T124
K
L
L
E
T
K
W
T
L
L
Q
E
Q
K
S
Site 22
S131
T
L
L
Q
E
Q
K
S
A
K
S
S
R
L
P
Site 23
S134
Q
E
Q
K
S
A
K
S
S
R
L
P
D
I
F
Site 24
S135
E
Q
K
S
A
K
S
S
R
L
P
D
I
F
E
Site 25
Y180
V
E
D
F
K
N
K
Y
E
D
E
I
N
R
R
Site 26
T188
E
D
E
I
N
R
R
T
A
A
E
N
E
F
V
Site 27
Y205
K
K
D
V
D
A
A
Y
M
S
K
V
E
L
E
Site 28
S207
D
V
D
A
A
Y
M
S
K
V
E
L
E
A
K
Site 29
T227
D
E
I
N
F
L
R
T
L
N
E
T
E
L
T
Site 30
T231
F
L
R
T
L
N
E
T
E
L
T
E
L
Q
S
Site 31
T234
T
L
N
E
T
E
L
T
E
L
Q
S
Q
I
S
Site 32
S238
T
E
L
T
E
L
Q
S
Q
I
S
D
T
S
V
Site 33
S241
T
E
L
Q
S
Q
I
S
D
T
S
V
V
L
S
Site 34
T243
L
Q
S
Q
I
S
D
T
S
V
V
L
S
M
D
Site 35
S244
Q
S
Q
I
S
D
T
S
V
V
L
S
M
D
N
Site 36
S248
S
D
T
S
V
V
L
S
M
D
N
S
R
S
L
Site 37
S252
V
V
L
S
M
D
N
S
R
S
L
D
L
D
G
Site 38
S254
L
S
M
D
N
S
R
S
L
D
L
D
G
I
I
Site 39
Y283
R
A
E
A
E
A
W
Y
Q
T
K
F
E
T
L
Site 40
T304
H
G
D
D
L
R
N
T
R
N
E
I
S
E
M
Site 41
Y375
M
A
R
Q
L
R
E
Y
Q
E
L
M
S
V
K
Site 42
S380
R
E
Y
Q
E
L
M
S
V
K
L
A
L
D
I
Site 43
Y392
L
D
I
E
I
A
T
Y
R
K
L
L
E
G
E
Site 44
S401
K
L
L
E
G
E
E
S
R
L
A
G
D
G
V
Site 45
S418
V
N
I
S
V
M
N
S
T
G
G
S
S
S
G
Site 46
T419
N
I
S
V
M
N
S
T
G
G
S
S
S
G
G
Site 47
S422
V
M
N
S
T
G
G
S
S
S
G
G
G
I
G
Site 48
S424
N
S
T
G
G
S
S
S
G
G
G
I
G
L
T
Site 49
S442
T
M
G
S
N
A
L
S
F
S
S
S
A
G
P
Site 50
S444
G
S
N
A
L
S
F
S
S
S
A
G
P
G
L
Site 51
S456
P
G
L
L
K
A
Y
S
I
R
T
A
S
A
S
Site 52
T459
L
K
A
Y
S
I
R
T
A
S
A
S
R
R
S
Site 53
S461
A
Y
S
I
R
T
A
S
A
S
R
R
S
A
R
Site 54
S463
S
I
R
T
A
S
A
S
R
R
S
A
R
D
_
Site 55
S466
T
A
S
A
S
R
R
S
A
R
D
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation