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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANXA5
Full Name:
Annexin A5
Alias:
Anchorin CII; Annexin 5; Annexin V; Annexin-5; ANX5; Calphobindin I; CBP-I; Endonexin II; ENX2; Lipocortin V; PAP-I; Placental anticoagulant protein I; PP4; Thromboplastin inhibitor; VAC-alpha; Vascular anticoagulant-alpha
Type:
Calcium-binding protein; Lipid binding protein
Mass (Da):
35937
Number AA:
320
UniProt ID:
P08758
International Prot ID:
IPI00329801
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005544
GO:0004859
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0007596
GO:0050819
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
Q
V
L
R
G
T
V
T
D
F
P
G
F
D
E
Site 2
T23
D
E
R
A
D
A
E
T
L
R
K
A
M
K
G
Site 3
T33
K
A
M
K
G
L
G
T
D
E
E
S
I
L
T
Site 4
S37
G
L
G
T
D
E
E
S
I
L
T
L
L
T
S
Site 5
T40
T
D
E
E
S
I
L
T
L
L
T
S
R
S
N
Site 6
T43
E
S
I
L
T
L
L
T
S
R
S
N
A
Q
R
Site 7
S44
S
I
L
T
L
L
T
S
R
S
N
A
Q
R
Q
Site 8
S46
L
T
L
L
T
S
R
S
N
A
Q
R
Q
E
I
Site 9
S71
D
L
L
D
D
L
K
S
E
L
T
G
K
F
E
Site 10
S88
I
V
A
L
M
K
P
S
R
L
Y
D
A
Y
E
Site 11
Y91
L
M
K
P
S
R
L
Y
D
A
Y
E
L
K
H
Site 12
Y94
P
S
R
L
Y
D
A
Y
E
L
K
H
A
L
K
Site 13
T111
G
T
N
E
K
V
L
T
E
I
I
A
S
R
T
Site 14
S116
V
L
T
E
I
I
A
S
R
T
P
E
E
L
R
Site 15
T118
T
E
I
I
A
S
R
T
P
E
E
L
R
A
I
Site 16
Y129
L
R
A
I
K
Q
V
Y
E
E
E
Y
G
S
S
Site 17
Y133
K
Q
V
Y
E
E
E
Y
G
S
S
L
E
D
D
Site 18
S135
V
Y
E
E
E
Y
G
S
S
L
E
D
D
V
V
Site 19
S136
Y
E
E
E
Y
G
S
S
L
E
D
D
V
V
G
Site 20
S146
D
D
V
V
G
D
T
S
G
Y
Y
Q
R
M
L
Site 21
T196
T
D
E
E
K
F
I
T
I
F
G
T
R
S
V
Site 22
S204
I
F
G
T
R
S
V
S
H
L
R
K
V
F
D
Site 23
Y213
L
R
K
V
F
D
K
Y
M
T
I
S
G
F
Q
Site 24
T215
K
V
F
D
K
Y
M
T
I
S
G
F
Q
I
E
Site 25
T224
S
G
F
Q
I
E
E
T
I
D
R
E
T
S
G
Site 26
T229
E
E
T
I
D
R
E
T
S
G
N
L
E
Q
L
Site 27
S230
E
T
I
D
R
E
T
S
G
N
L
E
Q
L
L
Site 28
S246
A
V
V
K
S
I
R
S
I
P
A
Y
L
A
E
Site 29
T254
I
P
A
Y
L
A
E
T
L
Y
Y
A
M
K
G
Site 30
Y256
A
Y
L
A
E
T
L
Y
Y
A
M
K
G
A
G
Site 31
Y257
Y
L
A
E
T
L
Y
Y
A
M
K
G
A
G
T
Site 32
S275
T
L
I
R
V
M
V
S
R
S
E
I
D
L
F
Site 33
T294
E
F
R
K
N
F
A
T
S
L
Y
S
M
I
K
Site 34
S295
F
R
K
N
F
A
T
S
L
Y
S
M
I
K
G
Site 35
Y297
K
N
F
A
T
S
L
Y
S
M
I
K
G
D
T
Site 36
S298
N
F
A
T
S
L
Y
S
M
I
K
G
D
T
S
Site 37
S305
S
M
I
K
G
D
T
S
G
D
Y
K
K
A
L
Site 38
Y308
K
G
D
T
S
G
D
Y
K
K
A
L
L
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation